Cooperative and interdisciplinary network of European multi-stakeholders aiming to implement precision medicine in the management of #BiliaryCancer #COST
Joined February 2024
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💡Exploring ERBB2/HER2 in cholangiocarcinoma! 🧬
Through a Virtual Mobility Grant from COST Action CA22125 (#PrecisionBTCNetwork), researchers investigated ERBB2 expression, genomic alterations, prognostic value and immune associations to advance precision oncology.
🎥 Turning cancer research into accessible science!
Meet Dr. Samuel McInerney, Specialist Registrar in Medical Oncology at Beatson West of Scotland Cancer Centre, PhD candidate at the University of Edinburgh, and Honorary Clinical Lecturer at the University of Glasgow.
🧬 As a #PrecisionBTC Virtual Mobility Grant recipient, he combined oncology research and generative AI to create an animated educational video on biliary tract cancers, making complex science accessible to the public and raising awareness of this rare, under-recognised cancer.
🌍 Released to coincide with World Cholangiocarcinoma Day, the video helped raise awareness of this rare and under-recognised cancer, highlighting the importance of making scientific knowledge accessible to a wider audience.
▶️ Watch the videos: youtube.com/playlist?list=PL…
🔬 Precision-BTC Mobility Grants Spotlight
Meet Natalia Soledad Tissera, STSM Grantee from VHIO, Barcelona, who completed her mission at UCL & UCLH Macmillan Cancer Centre, London, under the supervision of Prof. John Bridgewater.
During her stay, Natalia:
🧬 Gained experience in clinical research and trial implementation.
🔬 Contributed to an international 84-patient study on dMMR/MSI-H biliary tract cancer.
📊 Supported work on the BILCAP dataset and future research on early recurrence.
📢 New publication!
We’re pleased to have supported the open access publication of this international collaborative study on matched targeted therapies following first-line chemoimmunotherapy in advanced biliary tract cancer (BTC).
📈 Matched targeted therapy improved outcomes after chemoimmunotherapy failure, particularly in second line.
📌 These findings show how early molecular profiling in advanced BTC is key to identifying actionable alterations and guiding timely targeted treatment.
🔬 Read the full article: journal-of-hepatology.eu/art…
🌐 Discover the full story on the Precision-BTC Network website: precision-btc.eu/news/138
🧬 A 6-month virtual programme connecting young researchers, clinicians and nurses with experienced mentors, while bringing together professionals committed to advancing the future of biliary tract cancer research.
👥 Apply as a mentee or mentor by 31st October 2026!
🔗 New mentorship page & applications: precision-btc.eu/mentorship
📄 Program details: precision-btc.eu/assets/site…
Meet Gonçalo Carvalho, an MSc student from the Faculdade de Farmácia da Universidade de Lisboa, who completed a Short-Term Scientific Mission (STSM) from Lisbon, Portugal, to San Sebastián, Spain.
During his mission, Gonçalo investigated the functional effects of microRNAs in cholangiocarcinoma (CCA), combining:
🔬 Bioinformatic analysis of miRNA expression
🧪 In vitro assessment of miRNA modulation
🧬 In vivo validation of selected miRNAs