Passion for cancer research and clinical oncology. Radiation Oncology at MSKCC. #CancerOutcomes #NeuroOnc #CancerMetabolism
Joined April 2020
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Connor Kinslow, MD retweeted
As treatment options continue to evolve, keeping prognostic tools up to date is essential for guiding treatment for patients with brain metastases. Grateful to be part of this incredible team!
#BrainMetastases #Radonc #GPA #prognosis @OhioStateRadOnc
sciencedirect.com/science/ar…
Connor Kinslow, MD retweeted
1/6:
I am excited to share our multi-institutional F-SHARP phase I/II trial, now published in @JCO_ASCO!
doi.org/10.1200/JCO-25-02730
There are limited prospective data defining the optimal management of intraprostatic radiorecurrence (IPR) after definitive RT for prostate cancer.
We asked:
1. Is dose-escalated focal salvage high dose rate brachytherapy safe and effective for IPR?
2. Can Decipher (@Veracyte) identify patients with higher risk of recurrence with salvage ReRT that may benefit from therapeutic intensification?
🧵👇
Connor Kinslow, MD retweeted
Fantastic work led by @dtbergman analyzing 3,893 patients treated with Linac SRS for brain mets. OS plateaus from 5-20 lesions & salvage WBRT is rare. Data support an SRS-first strategy over fixed lesion limits! doi.org/10.1093/noajnl/vdag2… @MSKCancerCenter @MSK_RadOnc
Connor Kinslow, MD retweeted
Excited to share our new paper out today in @NatureMetabolism! "Hyperglycosylation is a metabolic driver of Alzheimer’s disease"
*We bridged spatial metabolomics (MALDI-MSI glycomics + lipidomics + isotopic pulse-chase tracing) directly to experimental biochemistry (genetic knockdown of glycan enzymes + glucosamine supplementation in AD models) and real-world public health data (EHR analysis showing glucosamine use linked to faster MCI-to-AD progression and worse survival).
**Key takeaway: The AD brain shows conserved hyperglycosylation driven by ramped-up glycan biosynthesis — not just a byproduct, but a causal driver. Reducing it helps cognition; boosting it (e.g., via glucosamine) worsens outcomes.
***We applied cutting-edge spatial tech to functional validation and clinical translation.
Full open-access paper: nature.com/articles/s42255-0…
Huge thanks to the incredible team, collaborators (incl. Matt Gentry, Stefan Prokop, @ji0ngbi0n , Yi Guo, @lichenbiostat, Ralph Deberardinis & others), and the patients/families who make this work possible.
Connor Kinslow, MD retweeted
Excited to share our new paper with @Mitch_P and @Luke_Pike_MD @pike_lab!
Nearly 4,000 brain mets patients treated with linac-based SRS at MSK: contemporary survival outcomes, prognostic factors, and what happens next with salvage treatment. 🧵
doi.org/10.1093/noajnl/vdag2…
Connor Kinslow, MD retweeted
Microwave ablation versus stereotactic body radiotherapy for oligometastatic colorectal liver metastases (LAVA-CRLM): a prospective, randomised, phase II trial
thelancet.com/journals/lanep…
Connor Kinslow, MD retweeted
We have waited more than a decade for this: ROAM is presented in Rome #EANO2026! See the results of ROAM/EORTC-1308, now also published in @TheLancet!
@EANOassociation
thelancet.com/journals/lance…
Connor Kinslow, MD retweeted
Prognostic and Predictive Effect of Age in Molecularly Defined Lower-Grade Gliomas. Co-authored by @TonyWangMD.
Read the full article. bit.ly/4g5e6gU
Connor Kinslow, MD retweeted
Is age prognostic for lower grade IDH mutant glioma?
NO, according to this pooled analysis
In molecular era age alone should not influence decision-making adjuvant treatment
Age is surrogate for IDH status ascopubs.org/doi/10.1200/JCO…
Connor Kinslow, MD retweeted
Does author specialty shape conclusions?
@JNCI_Now found urology-led authorship was linked to pro-prostatectomy conclusions in 105 studies comparing surgery vs radiation for #ProstateCancer.
🔗 oxford.ly/4yIU7fl
Connor Kinslow, MD retweeted
Great program at @NeuroOnc Latin America in #brazil. Amazing event and glad to catch up with colleagues discussing some novel treatment options of brain tumors. @Kenneth_Aldape @RadOncConnor @DrShaanRaza @delaFuenteNOnc @joao_p_almeida @SylvesterCancer @EmanuelAbr31592
Connor Kinslow, MD retweeted
Which part of the human body is this?
Photomicrograph from @ziad_zaatari
Connor Kinslow, MD retweeted
New paper on this coming out very soon, stay tuned !
What if we could download the brain?
At the @UF College of Medicine, @RCSunlab is digitally mapping the brain molecule by molecule to uncover hidden clues about disease progression — and help create a future with more time, memory and hope. #BreakthroughsBeginHere
Connor Kinslow, MD retweeted
Using AI to do real work is awesome if you like playing "two truths and one lie" all day.
Connor Kinslow, MD retweeted
Definitive radiotherapy with or without chemotherapy in anterior nasal cavity cancers achieved high rates of long-term organ preservation & favorable local recurrence rates for patients who declined rhinectomy or had unresectable disease. ja.ma/4aSQIQY
Connor Kinslow, MD retweeted
IDH-mutant gliomas arise from glial progenitor cells harboring the initial driver mutation | Science science.org/doi/10.1126/scie…
Connor Kinslow, MD retweeted
What’s the role of the extent of resection in grade 2 IDH-mutant glioma? I’m delighted to see this work published in @TheLancetOncol — thanks and congratulations to the team!
@NeuroOnc @EANOassociation @NSTumorSection @pkarschnia @jakeyoung11
thelancet.com/journals/lanon…
Connor Kinslow, MD retweeted
Our new ESTRO CNS Focus Group analysis uncovers how reirradiation is used in primary brain tumors – read the full paper: thegreenjournal.com/article/…
@ESTRO_RT @ASTRO_org @NeuroOnc @EANOassociation @MaxNiyazi @gminniti2012 @andradaturcas
