Reset Therapeutics (@ResetTx) header
Reset Therapeutics (@ResetTx) profile picture

Reset Therapeutics

@ResetTx

Harnessing the power of the body’s circadian system – its network of internal clocks – to discover, develop, & commercialize therapeutics. Timing is Everything.

 South San Francisco, CA
resettherapeutics.com
Joined January 2015
  • Tweets1.9K
  • Following3.4K
  • Followers909
Massive Genetic Study Shows How Humans are Evolving scientificamerican.com/artic…
Massive Genetic Study Shows How Humans are Evolving

Massive Genetic Study Shows How Humans are Evolving

Analysis of 215,000 people's DNA suggests variants that shorten life are being selected against

scientificamerican.com
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Reset Therapeutics retweeted
John Hogenesch (@jbhclock) profile picture
John Hogenesch@jbhclock31 Aug 2017
Please join us for the 2017 IEBMC Meeting on Biological Clocks in Rejeka, Croatia, 10/6 to 8. Please RT! iebmc.org/
Image from John Hogenesch (@jbhclock)
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Temperature-Sensitive Substrate and Product Binding Underlie Temperature-Compensated Phosphorylation in the Clock cell.com/molecular-cell/full…
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Aging: rewiring the circadian clock - ncbi.nlm.nih.gov/pubmed/2888…
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Later circadian timing of food intake is associated with increased body fat - ncbi.nlm.nih.gov/pubmed/2887…
Later circadian timing of food intake is associated with increased body fat - PubMed

Later circadian timing of food intake is associated with increased body fat - PubMed

Background: Weight gain and obesity have reached alarming levels. Eating at a later clock hour is a newly described risk factor for adverse metabolic health; yet, how eating at a later circadian time...

pubmed.ncbi.nlm.nih.gov
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Meeting a microbe in the morning or in the evening: Is it all the same? - eurekalert.org/pub_releases/… @Filipa_Ferr @CircadianClocks
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Later circadian timing of food intake is associated with increased body mass index - eurekalert.org/pub_releases/… @SatchinPanda
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Boosting a mitochondria-targeting protein could postpone aging - fiercebiotech.com/research/b…
Boosting a mitochondria-targeting protein could postpone aging

Boosting a mitochondria-targeting protein could postpone aging

As people age, their mitochondria—the organelles that produce energy in cells—tend to become damaged and accumulate in muscles and organs. | UCLA researchers extended the lifespans of middle-aged...

fiercebiotech.com
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Immune cells help fat deal with environmental challenges - eurekalert.org/pub_releases/…
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Boehringer, Gubra strike backloaded €250M obesity deal - fiercebiotech.com/biotech/bo…
Boehringer, Gubra strike backloaded €250M obesity deal

Boehringer, Gubra strike backloaded €250M obesity deal

Boehringer Ingelheim has committed up to €250 million ($300 m | Boehringer Ingelheim has committed up to €250 million ($300 million) to work with Gubra on obesity treatments. The deal gives Boehrin...

fiercebiotech.com
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Macromolecular Assemblies of the Mammalian Circadian Clock cell.com/molecular-cell/full…
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Distinct Circadian Signatures in Liver and Gut Clocks Revealed by Ketogenic Diet - ncbi.nlm.nih.gov/pubmed/2887…
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Metabolic Alterations and Cardiovascular Outcomes of Cortisol Excess - ncbi.nlm.nih.gov/pubmed/2721…
Metabolic Alterations and Cardiovascular Outcomes of Cortisol Excess - PubMed

Metabolic Alterations and Cardiovascular Outcomes of Cortisol Excess - PubMed

Cushing's syndrome (CS) is a severe chronic and systemic condition caused by endogenous or exogenous excess of glucocorticoids, associated with increased morbidity and mortality. Patients with active...

pubmed.ncbi.nlm.nih.gov
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Trigger for fatty liver in obesity eurekalert.org/pub_releases/…
UCLA biologists slow aging, extend lifespan of fruit flies eurekalert.org/pub_releases/…
Nonalcoholic Fatty Liver Disease as a Nexus of Metabolic and Hepatic Diseases cell.com/cell-metabolism/abs…
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23andMe is raising about $200 million, led by Sequoia @jbhclock @annewoj23 @FaitherzPhD techcrunch-com.cdn.ampprojec…
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Lead discovery and chemical biology approaches targeting the Ubiquitin Proteasome System sciencedirect.com/science/ar…
The genomic landscape of human cellular circadian variation points to a novel role for the signalosome - elifesciences.org/articles/2…
The genomic landscape of human cellular circadian variation points to a novel role for the signal...

The genomic landscape of human cellular circadian variation points to a novel role for the signal...

Cellular genetics highlights differences in protein catabolism in general, and the COP9 signalosome in particular, as one major source of human cellular circadian variation.

elifesciences.org
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Connexin 43-Mediated Astroglial Metabolic Networks Contribute to the Regulation of the Sleep-Wake Cycle - ncbi.nlm.nih.gov/pubmed/2886…
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