A great place to keep track of the emerging science of NAD replenishment, organizing hundreds of research studies. [email protected]
Joined November 2022
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Oral NR treatment at 3000 mg daily for 4 weeks was safe, and NR even at a dose of 3000 mg for 4 weeks did not cause depletion of the methyl-group pool
nature.com/articles/s41467-0…
Nicotinamide riboside alleviates persistent pain in mice newscientist.com/article/240…
Forbes covers the re-inventing of the wheel. If only there were an oral health supplement that effectively replenished NAD...
forbes.com/sites/geristengel…
Patients with the rare metabolic disorder Arts Syndrome appear to have clinical improvement with SAMe and nicotinamide riboside
onlinelibrary.wiley.com/doi/…
Radiation: Mouse study shows NR's potential to be a therapeutic agent for delayed effects of acute radiation exposure in patients receiving radiotherapy and exposed populations onlinelibrary.wiley.com/doi/…
Science of NAD retweeted
🔬 Curious about cellular health and nicotinamide riboside? 🔬Participate in an insightful AMA with @CharlesMBrenner on the r/nicotinamideriboside subreddit. Ask your burning questions about Tru Niagen and discover how it supports your vitality. Join the conversation! bit.ly/3svUVq5 #AMA #CellularHealth #TruNiagen #nicotinamideriboside
It has been more than two years since scientists told us that vitamin B3 could treat sepsis. Since then, we have helped a lot of septic rodents. Now the CDC is trying to take sepsis more seriously.
scienceofnad.com/post/sepsis…
Science of NAD retweeted
.@CharlesMBrenner is hosting an AMA Q&A at the NR subreddit. Lots of great questions already: reddit.com/r/NicotinamideRib…
Dr. Charles Brenner answers your questions live on Reddit, Monday September 4, 10am Pacific, at reddit.com/r/NicotinamideRib…
ALT Dr. Charles Brenner's reddit AMA on Monday September 4 from 10am-11:30am Pacific, at https://www.reddit.com/r/NicotinamideRiboside
NR supplementation blunts Th1 and Th17 immune responsiveness in healthy volunteers and in psoriasis. The concept is now being explored in vivo, where mild to moderate psoriasis patients are being investigated in a placebo-controlled study. https:// cell.com/cell-reports-medici…
Meta-analyses of 29 random controlled trials with 8,664 participants indicated a significant reduction in systolic and diastolic blood pressure for the NAD+ precursors supplementation compared with the control group. onlinelibrary.wiley.com/doi/…
Stem Cells: NAD+ metabolism governs the anti-inflammatory function of mesenchymal stem cells during inflammation nature.com/articles/s41423-0…
Preprint: "The evidence that psoriasis lesions show NADH/NAD+ redox imbalance towards oxidation may have important therapeutic implications....Increasing the level of NAD+ in psoriatic lesions could be considered as a therapeutic option..." researchgate.net/publication…
Nicotinamide Riboside Improves Stemness of Human Adipose-Derived Stem Cells and Inhibits Terminal Adipocyte Differentiation mdpi.com/1424-8247/16/8/1134
Diabetes: NR supplementation boosted NAD metabolism to augment mitochondrial function, reducing inflammation and thereby preventing progression of diabetic kidney disease in mice reddit.com/r/NicotinamideRib…
Indiscriminately reproducing falsehoods on social media is harmful. We all make mistakes, though, so if someone points out that you have posted a conclusion disclaimed by the study's most prominent author, the proper response would be to say thank you, not to block the messenger.
"We have demonstrated a time-of-day dependent response to NAD+ therapy." Clinical trials that report conflicting results from NAD treatment mostly overlook the time of drug intake. Proposed: time of treatment dictates the amplitude of metabolic benefits. reddit.com/r/NicotinamideRib…
A rare head-to-head comparison of NMN and NR finds that NR is slightly more effective than NMN in maintaining DNA integrity in cisplatin-treated cells. assets.researchsquare.com/fi…