The World's Most Prolific Teacher of Medicine Tweets only reflect personal opinions. Executive Producer https://xitter.cf/t.co/OMt5h9rXph
Everywhere!
Joined February 2009
- Tweets36.6K
- Following534
- Followers104K
- Likes7.5K
Conrad Fischer retweeted
Heartiest congratulations to my dear friend Dr. @SeeFisch on receiving the prestigious 2027 ACGME (@acgme) Parker J. Palmer Courage to Teach Award!
Dr. Fischer is, in my opinion, one of the finest medical educators and Internal Medicine Residency Program Directors in the country. Beyond his exceptional teaching abilities, what truly sets him apart is his unwavering advocacy for International Medical Graduates (IMGs).
The ACGME's Parker J. Palmer Courage to Teach Award recognizes outstanding Residency Program Directors who demonstrate innovation, excellence in medical education, and exemplary mentorship of residents and fellows.
As the Internal Medicine Program Director at One Brooklyn Health–Brookdale Hospital Medical Center, Dr. Fischer has made a meaningful difference in the lives of countless aspiring and practicing physicians.
A richly deserved recognition for an educator, mentor, and genuine champion of IMGs.
Congratulations, my friend! Wishing you continued success and many more milestones ahead!
acgme.org/newsroom/2026/10/a…
Bruton's Tyrosine Kinase (BTK) inhibitors:
*Zanubrutinib, Ibrutinib, Acalabrutinib, Pirtobrutinib
*They shut down the signaling pathway that tells B-cells to multiply
*Chronic lymphocytic leukemia (CLL)
*Lymphoma including mantle cell lymphoma
$25,000 a MONTH!!!!!
Sonrotoclax and Venetoclax: BCL inhibitors
*BCL-2 is an anti-apoptotic protein
*Apoptosis is the natural death of cells
*Cancer cells like lymphoma or CLL are like "Zombies" that do not know when to die
Mantle cell Lymphoma
*Type of NON Hodgkins lymphoma
*Named for MANTLE ZONE of lymph nodes
*Treat with AUTOLOGOUS Stem cell transplant or...
*R-CHOP
Mantle cell lymphoma (MCL)
*Behaves like low-grade (slow-growing) B-cell lymphoma under a microscope
*Yet spreads aggressively like high-grade lymphoma
*MCL driven by specific genetic mutation—the chromosomal translocation t(11;14)—which causes an overexpression of a protein called cyclin D1
COVID vaccine
*Very confused recommendations
*Family Practice: immunocompromised, Age>65
*Obstetrics: all pregnant
*Infectious Disease Society: Everyone who is immunocompromised
#USMLE will NEVER put a question with competing guidelines
$221 a SHOT would make me conspiratorial
Tambotatug pelitecan
*Add six months life to Small Cell Cancer
*Targets the immune-checkpoint molecule
What APPROVED uses for BISPECIFIC antibodies?
*Relapsed/Refractory MYELOMA (BCMA (B-cell maturation antigen)
*Relapse ALL (blinotumumab)
*Lymphoma
*Lung cancer
*Biliary and Pancreatic cancer
*Retinal Eye Diseases (Macular Degeneration)
A M A Z I N G advances all APPROVED!!
Emicizumab
*Bispecific monoclonal antibody
*Acts as molecular bridge to restore blood-clotting process with hemophilia
*Mimics Factor VIIIa
*Binds sites simultaneously to activated factor IX (FIXa) and X
Blinatumomab
*Bispecific T-cell engager (BiTE)
*CD19 (expressed on the surface of B-lineage)
*Lymphoblastic leukemia
*Other arm binds to CD3 (T-cell receptor [TCR] complex on cytotoxic T-cells)
KILLS LEUKEMIA LYMPHS AND DOES NOT HURT NORMAL TISSUE
Amazing Ad for an amazing candidate @AbdulElSayed
BLINATUMUmab
*Another bispecific antibody
*Binds antigen on B- lymphocytes (CD19) and other to CD3 antigen on T cells.
(B-cell AND T-cell inhibitor)
*Treats Acute Lymphocytic leukemia
Obexelimab
*Bifunctional monoclonal antibody
*All bifunction lab-made artificial
*Non–B-cell-depleting treatment for IgG4-related disease (Rituximab DESTROYS B-cells)
*Binds to CD19 on B cells and the inhibitory receptor FcγRIIb on cell surfaces
*50% reduction in flair
Take a look
We're thrilled to launch Perpetua Pulse! ⚡
A free, interactive EP simulator for knowledge and practice: connect ECGs with intracardiac EGMs, explore rhythms, and work through device cases. 🫀
Enter the EP Arcade 👇
pulsepoint.perpetuaheart.com
#CardioTwitter #MedEd #Cardio #ECG
Conrad Fischer retweeted
Every person of conscience and faith must condemn this horrific act of terrorism. These brainwashed criminals share none of the values we hold.
We stand with the Christian community of the Karak Church & with Jordan, and we pray for the healing of the victims and their families.
BREAKING: At least six people killed and 28 others wounded after a shooting in Jordan’s Karak governorate that saw gunmen open fire during a funeral at a church.
Read aje.news/0wymgc
The ACGME Parker Palmer award has been one in medicine seven times since the awards inception in the New York area
Every single time it is gone to a university program in Manhattan never in Brooklyn or Queens or the Bronx or Staten Island
Congratulations to the 2027 recipients of the #ACGME Awards!
These exceptional individuals have demonstrated outstanding leadership, innovation, service, and dedication to advancing graduate medical education and physician education. Their contributions continue to strengthen #GME and inspire residents, fellows, educators, administrators, and others.
The ACGME will formally celebrate these awardees at #ACGME2027, taking place February 25-27, 2027, in San Antonio, Texas. Read more: acgme.org/newsroom/2026/10/a… #MedEd #MedX
There are 13,000 program directors eligible for this word each year
There were only 10 awards given, which means one impedes one in Surgery one in Psych one NOB one an emergency medicine, etc.
The courage to teach awards is the highest award in the country if not the world for leadership and innovation in medical education at the graduate level
Congratulations to the 2027 recipients of the #ACGME Awards!
These exceptional individuals have demonstrated outstanding leadership, innovation, service, and dedication to advancing graduate medical education and physician education. Their contributions continue to strengthen #GME and inspire residents, fellows, educators, administrators, and others.
The ACGME will formally celebrate these awardees at #ACGME2027, taking place February 25-27, 2027, in San Antonio, Texas. Read more: acgme.org/newsroom/2026/10/a… #MedEd #MedX
Conrad Fischer retweeted
Thank you Dr Fischer, would have never been able to do it without your support and encouragement, truly grateful to you❤️❤️❤️
I think we would all be interested to learn the specifics of what changes in therapy
