TheBioConnection

Researchers at University of California San Diego School of Medicine, with colleagues elsewhere, have used gene therapy to prevent learning and memory loss in a mouse model of Alzheimer’s disease (AD), a key step toward eventually testing the approach # thebioconnection.com/gene-th…

An intestinal bowel disease that affects up to 10 percent of premature infants at a very vulnerable and developmentally crucial time can lead to serious infection and death. #Infants #Infections #IntestinalDisease #stemcells thebioconnection.com/stem-ce…

A synthetic DNA vaccine candidate for Middle East respiratory syndrome coronavirus (MERS-CoV) developed at The Wistar Instituteinduced potent immune responses and afforded protective efficacy in non-human primate (NHP) models when given intradermally #c thebioconnection.com/low-dos…

A UCLA-led research team has identified a chemical cocktail that enables the production of large numbers of muscle stem cells, which can self-renew and give rise to all types of skeletal muscle cells. #StemCell thebioconnection.com/chemica…

Special Olympics is the biggest untold secret in healthcare. For over 20 years, the organization has been getting people with intellectual disabilities healthy and lowering their risk of deadly – and costly – conditions like cardiovascular #COVID19 #Spe thebioconnection.com/special…

A long noncoding RNA whose function was previously unknown turns out to play a vital role in mobilizing the immune response following a bone marrow transplant or solid organ transplantation. #Graftversushostdisease #immunesystem #organs #Tcells thebioconnection.com/researc…

A new type of CAR T-cell therapy more than triples the expected length of remission for multiple myeloma patients who have relapsed several times, according to an international clinical trial with UT Southwestern as the lead enrolling site. #cartcell #C thebioconnection.com/new-car…

A novel computer algorithm that could create a broadly reactive influenza vaccine for swine flu also offers a path toward a pan-influenza vaccine and possibly a pan-coronavirus vaccine as well, according to a new paper published in #coronavirus #Ebola # thebioconnection.com/vaccine…

Researchers at the University of California San Diego School of Medicine and Massachusetts General Hospital have identified a new drug that could prevent Alzheimer’s disease by modulating, rather than inhibiting, a key enzyme involved in forming #Alzhei thebioconnection.com/potenti…

Genetic alterations of the KRAS gene are some of the most common mutations in lung cancer patients, but unfortunately these patients have few effective treatment options. #DrugDevelopment #KRASmutation #lungcancer thebioconnection.com/lung-ca…

Considered the most lethal form of DNA damage, double-strand breaks must be repaired to prevent cell death. In developing therapies for hard-to-treat breast and ovarian cancers in patients with BRCA gene mutations, scientists aim to identify ways to #Br thebioconnection.com/study-i…

(StatePoint) Diabetes management and foot care go hand in hand. “Diabetes can cause nerve damage and poor circulation that puts people at risk for a wide range of foot problems,” says Barry I. #diabetes #footcare thebioconnection.com/the-dos…

Rutgers Cancer Institute of New Jersey, the state’s only National Cancer Institute-designated Comprehensive Cancer Center, has treated its first upper tract urothelial cancer patient with a recently approved therapy option known as mitomycin gel, #cance thebioconnection.com/first-p…

Many patients with multiple myeloma, a type of blood cancer, eventually develop resistance to one treatment after another. That’s in part because cancer stem cells drive the disease — cells that continually self-renew. #CancerCells #CellBiology #genetic thebioconnection.com/designe…

Eliminating a single gene can turn exhausted cancer-fighting immune cells known as CD8+ T cells back into refreshed soldiers that can continue to battle malignant tumors, a new study led by UT Southwestern researchers suggests. #DrugDevelopment #DrugTar thebioconnection.com/revivin…

(StatePoint) Diabetes management and foot care go hand in hand. “Diabetes can cause nerve damage and poor circulation that puts people at risk for a wide range of foot problems,” says Barry I. #diabetes #footcare thebioconnection.com/?p=1917…

Enhancers are regulatory elements that play an important role in cancer. Researchers from Rutgers Cancer Institute of New Jersey, the state’s only National Cancer Institute-designated Comprehensive Cancer Center, identified a novel enhancer #Leukemia #TAL thebioconnection.com/explori…

Enhancers are regulatory elements that play an important role in cancer. Researchers from Rutgers Cancer Institute of New Jersey, the state’s only National Cancer Institute-designated Comprehensive Cancer Center, identified a novel enhancer #Leukemia #TAL thebioconnection.com/explori…