The Riley Lab investigates the medicinal chemistry of natural products focused on pain and addiction.

Chicago, IL
Joined December 2018
Role call!!! UIC is Iowa-bound for the annual MIKIW meeting!! #MIKIW2026
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Spent a fantastic weekend at KU for the annual MIKIW conference. It was a blast showing the group where the magic all started. And we capped it off with Lisa Rusali bringing home the gold with an awesome oral presentation. #MIKIW2025 #noplacelikehome
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The latest Riley Lab paper using a Ritter-like reaction to form aristoquionline analogues is now out in ACS Medicinal Chemistry Letters. pubs.acs.org/doi/10.1021/acs…
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Check out this Virtual Special Issue on Natural Products Driven Medicinal Chemistry!! pubs.acs.org/page/vsi/natura…
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Really excited to see our latest manuscript published today in the Journal of Medicinal Chemistry! Here we report the first structure-activity relationships for the naturally occurring kappa opioid receptor agonist, akuammicine. pubs.acs.org/doi/10.1021/acs…
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Great weather to cheer on ⁦@TheChicagoDogs⁩!!
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Hot day in Chicago. That means a group trip to Mario’s!
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Check out our group's latest pre-print describing the SAR of the natural product akuammicine! chemrxiv.org/engage/chemrxiv…
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I'm very excited to announce that our group has been awarded an R01 from NIDA entitled "Selective Targeting of Nicotinic Acetylcholine Receptor Subtypes for Cocaine Use Disorder"
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Check out this cover featuring artwork designed my Riley lab member Carolyn Straub! #MyACSCover
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