@TomDenes

Associate prof studying phage-host interactions, microbiology, and genomics. Outdoor enthusiast; loves hiking, backpacking, and observing the natural world.

 Knoxville, TN
Joined January 2013
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11Media
In case you were waiting for the combined, three position ad! UTK Microbiology is hiring TTF for Fall 2025. Come join us!!
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Evergreen 2025 is happening, and for the first time in its 50-year history, we're taking it on the road!🎉🎉 Save the date for the 26th Biennial Evergreen International Phage Meeting, which will be held August 3-8, 2025, at the University of Tennessee, Knoxville!
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We're hiring! For Fall 2025, Assistant/Associate Professor in the area of Microbe-Plant Interactions.
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20y of dedication/perseverance by @PaulPirnay , @mmerabish & team to make #phagetherapy a reality. A good moment to say thank you for our 30th joint publication.
Nature Microbiology@NatureMicrobiol4 Jun 2024
OUT NOW 👉 Personalized bacteriophage therapy outcomes for 100 consecutive cases: a multicentre, multinational, retrospective observational study @PaulPirnay @DjebaraSarah @StevenDeSoir @GlontiTea @JeroenWagemans @PJ_Ceyssens @RobLavigne1 @mmerabish #phage nature.com/articles/s41564-0…

Personalized bacteriophage therapy outcomes for 100 consecutive cases: a multicentre, multination...

Nature Microbiology - Analysis of 100 consecutive personalized bacteriophage therapy cases supports the use of personalized and sometimes pre-adapted, bacteriophage preparations, often in...

nature.com
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Thrilled to announce our latest publication @CMKhursigara led by our outstanding student Stevan Cucic (soon-to-be Dr. Cucic — keep an eye out for an excellent phage biologist joining us) 🙏 @Dozois_CM & ALL reviewers for invaluable comments&feedback(1/4) journals.asm.org/eprint/8SMX…

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journals.asm.org
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We are hiring. This time all three ads (abridged) in one place. Please RT and share far and wide!
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Close up of the newly-infected bacterial cell from "Bacteriophage T4 Infection." I drew the illustration in Photoshop at a scale of 1 pixel/nanometer.
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Tom Denes retweeted
Kovac Lab@kovac_lab14 Aug 2023
In Runan Yan’s latest study we found that the prevalence of #ciprofloxacin #resistance was significantly higher among #Campylobacter isolates from human clinical compared to poultry meat samples in Pennsylvania (193 isolates from >8,000 samples analyzed): authors.elsevier.com/a/1hai7… – at State College, PA
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Replying to @TomDenes
@TomDenes resistance & abiotic factor influence on Listeria phage applications in food safety; & use of directed evolution; starts with data from pubmed.ncbi.nlm.nih.gov/2588… #EvergreenPhage2023

Selection and Characterization of Phage-Resistant Mutant Strains of Listeria monocytogenes Reveal...

Listeria-infecting phages are readily isolated from Listeria-containing environments, yet little is known about the selective forces they exert on their host. Here, we identified that two virulent...

pubmed.ncbi.nlm.nih.gov
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#EvergreenPhage2023 Illuminating breakfast chat… with Betty Kutter, Sarah Kuhl, Paul Hyman & @TomDenes
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Tom Denes retweeted
ASM
@ASMicrobiology2 Jun 2023
#Phages are used to control bacterial pathogens at every stage of food production, from promoting livestock & crop health to killing pathogens on ready-to-eat foods. What are the benefits & challenges associated with deploying phages in the food industry? asm.social/1f8
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Public Service announcement: Do NOT use raw cow or goat milk to make your own infant formula; raw milk carries a substantial risk of containing pathogens that can cause serious illness or even death in a baby!
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Excited to share an interdisciplinary collaborative effort: Analysis of Derivatized Wall Teichoic Acids Confirms that a Mutation in Phage-Resistant Listeria monocytogenes Impacts Rhamnose Decoration pubs.acs.org/doi/10.1021/acs…

Analysis of Derivatized Wall Teichoic Acids Confirms that a Mutation in Phage-Resistant Listeria...

Abstract. Listeria monocytogenes is a Gram-positive foodborne pathogen that causes listeriosis, an illness that may result in serious health consequences o

pubs.acs.org
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Vaccine trifecta complete! JJ boosted with Pfizer boosted with Moderna. Enjoying pandemic stress respite. Now if only my kids were eligible…
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Tom Denes retweeted
Kovac Lab@kovac_lab10 Nov 2021
Phylogenetic Analysis Reveals Source Attribution Patterns for Campylobacter spp. in Tennessee and Pennsylvania mdpi.com/1346486 #Canpylobacter #sourceattribution @TomDenes @Lauren_Hudson08

Phylogenetic Analysis Reveals Source Attribution Patterns for Campylobacter spp. in Tennessee and...

Campylobacteriosis is the most common bacterial foodborne illness in the United States and is frequently associated with foods of animal origin. The goals of this study were to compare clinical and...

mdpi.com
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OUT NOW: Nationwide genomic atlas of soil-dwelling Listeria reveals effects of selection and population ecology on pangenome evolution. @JingqiuLiao @foodsafetyprof @oxcordero @Cornell_FSL Read it here: rdcu.be/coSvB nature.com/articles/s41564-0…
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How to train your bacteriophage PNAS Commentary by @AdairLBorges pnas.org/content/118/28/e210…
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Excited to have this paper out: Nature versus Nurture: Assessing the impact of strain diversity and pre-growth conditions on Salmonella, E. coli, and Listeria spp. growth and survival on selected produce items: aem.asm.org/content/early/20… Thank you @CPSnewsupdates for funding!
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Our latest paper on Salmonella ser. Javiana is our now in PeerJ. Great job @Lauren_Hudson08 et al! peerj.com/articles/10256/

Genomic characterization and phylogenetic analysis of Salmonella enterica serovar Javiana

Salmonella enterica serovar Javiana is the fourth most reported serovar of laboratory-confirmed human Salmonella infections in the U.S. and in Tennessee (TN). Although Salmonella ser. Javiana is a...

peerj.com
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Coevolving therapeutic phage with their host can improve the phage’s suppressive ability via slowing the rise of phage resistant genotypes through multiple mechanisms.
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