Neurologist //@HUNIMED 🇮🇹 @UCalgary 🇨🇦//#Neurology #Stroke 🧠🩸
Milan, Italy
Joined August 2021
- Tweets475
- Following771
- Followers787
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Umberto Pensato retweeted
Very proud to have been awarded with the Young Investigator Award by the world Stroke Organization for the abstract about our novel gHIR! A special thanks to @UPensato and @johanna_ospel for this great collaboration! Take a look on @_JCBFM at journals.sagepub.com/doi/10.…!
Umberto Pensato retweeted
🧠What stood out at #WSC2026 in Seoul?
#MondayTip brings you 10 key studies across the stroke pathway: from reperfusion to 2ry prevention
📊Explore the infographic
💬Which finding could have the biggest impact on your practice?
Highlights webinar👉Nov 10
us02web.zoom.us/webinar/regi…
🤖 Made with AI
Umberto Pensato retweeted
Terrific and inspiring talk by @demchuk_andrew at WSC2026 in Seoul
@UPensato
#stroke #perfusion #CTP #penumbra
#precisionmedicine
"Target Expansion Criteria" for #ICH patients who may benefit from acute therapies in late window. @GreenJournal @NawabiJawed @fmazzacane01 @Libero131087 @RaffaeleOrnello @giovmerl @matpaolucci @m_paciaroni @Simona_Sacco_ @MicheleRomoli @ZiniAndrea @QiLiMD
neurology.org/doi/10.1212/WN…
EVT treatment effect in MeVO #stroke across perfusion mismatch profiles in ESCAPE-MeVO! @JAMANetworkOpen @johanna_ospel @mayank_G0 @draravindganesh @MDStebnerAl @ESOstroke jamanetwork.com/journals/jam…
The granular HIR was the best performing measure of infarct growth rate in this #stroke study. Published in @_JCBFM, soon to be presented at @WorldStrokeOrg. @Libero131087 @johanna_ospel @bijoymenon @demchuk_andrew phttps://journals.sagepub.com/doi/10.1177/0271678X261492523
Umberto Pensato retweeted
🎙️ New Voice of Stroke #ESOPodcast episode asks: which patients with medium or distal vessel occlusion may benefit from #Thrombectomy? We explore ORIENTAL-MeVO & new evidence on imaging, collaterals & tissue preservation. Listen now:
🎵 Spotify: ow.ly/MpsK50ZPZRN
#Stroke
Umberto Pensato retweeted
Spot sign evolution patterns (I, II, and III) on multiphase CT angiography were significantly associated with hematoma expansion. @UPensato @HUNIMED @DCNSNeuro ahajrnls.org/4yC2lVF
Umberto Pensato retweeted
In this post-hoc analysis of the ANEXXA-I trial (andexanet alfa vs SOC [4F-PCC] for DOAC-related ICH) it was the density makers (hereogenous, hypodensity, and back hole sign) which predicted hematoma expansion (33% overall).
None of the irregular shape markers predicted expansion.
#CodeICH
onlinelibrary.wiley.com/doi/…
Super important ARCADIA post hoc! LV dysfunction is a treatment effect modifier of DOACs for #stroke prevention. (ie DOAC benefits only in ESUS with LV dysfunction) @StrokeAHA_ASA @StrokeAHA_ASA ahajournals.org/doi/10.1161/…
CT Markers of Hematoma Expansion and #Andexanet Response in #ICH : ANNEXa‐I Trial! blend sign looks interesting! @ArKatsanos @PargolBalali @Atirahcus @DavidSeiffge @carlosmictusvh @ECSandset @mike_sharma2 @Ash_Shoamanesh #stroke onlinelibrary.wiley.com/doi/…
Umberto Pensato retweeted
Evolution Patterns of Spot Sign to Stratify Intracerebral Hemorrhage Expansion Risk | @American_Heart @StrokeAHA_ASA @rondalun1 @NatusRex ahajournals.org/doi/10.1161/…
Umberto Pensato retweeted
A comprehensive review on breakthrough #stroke (stroke despite DOAC) and proposal of AF-BREACH criteria for RCTs @rondalun1 @capivato @SposatoL @demchuk_andrew @HUNIMED @HumanitasMilano @DCNSNeuro @UCalgary @bmj_latest @VancouverStroke @WorldStrokeEd
bmj.com/content/394/bmj-2025…
Umberto Pensato retweeted
Despite #stroke having a huge societal burden in #Italy, it is disproportionately underfunded, with few Italian stroke researchers working in their country. @caso_valeria @FishingNeurons @m_paciaroni @demchuk_andrew @ESOstroke @WorldStrokeOrg link.springer.com/article/10…
Umberto Pensato retweeted
Some thoughts on who should be admitted to Stroke Units and how fast! in respose to Europe Stroke Action Plan @ESOstroke @draravindganesh @nishita_singh3 academic.oup.com/esj/article…
Umberto Pensato retweeted
Thromboinflammation in Acute Stroke: From Pathophysiological Challenges to Emerging Therapeutic Opportunities | Stroke @StrokeAHA_ASA @AHAScience ahajournals.org/doi/10.1161/…
Evolution Patterns of Spot Sign to Stratify Intracerebral Hemorrhage Expansion Risk | @American_Heart @StrokeAHA_ASA @rondalun1 @NatusRex ahajournals.org/doi/10.1161/…
Umberto Pensato retweeted
Redefining the Cerebral Ischemic Core-Penumbra-Oligemia Continuum @StrokeAHA_ASA @johanna_ospel @draravindganesh @nishita_singh3 @AlmekhlafiMa @BroocksGabriel @Libero131087 @DGutierrez__V @NguyenThanhMD @VYogendrakumar @ZiniAndrea @KimBJstroke ahajournals.org/doi/10.1161/…
Umberto Pensato retweeted
I know you probably know all this without a meta-analysis to tell you...
This hot off the press metananlysis of all rFVIIa RCTs shows a significant reduction in ICH volume at 24 hours
No effect of functional outcome or mortality.
Most interesting:
No increase in thromboembolic SAEs.
jnnp.bmj.com/content/early/2…
Umberto Pensato retweeted
I think we can all agree that the "CTA-for-All" concept, which was originally published in Stroke in 2020, has WON and is now (thank goodness) the standard of care. For SO many reasons.
I just came across this nice opinion piece that articulates the benefits of getting CTA data right off the bat when the NCCT shows blood.
Not the least of which: a (+) a spot sign on a hyperacute scan (<2 hours) means very high risk for active bleeding.
A (+) spot when the baseline scan is performed after 3 hours from onset it doesn't mean nearly as much. Like an infiltrate on a CXR -- a radiographic sign that lingers.
To say nothing about CTA diagnosing weird DAVFs, AVMs, and the like.
CT Angiography-for-All: Beyond “Diagnostic Nihilism” in Acute #ICH – A Personal View
#CodeICH
karger.com/ced/article-abstr…
