@WenjunK
Joined August 2014
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12Media
So excited to see CellOracle out!! Congratulations @kenjikamimoto68!!
Samantha Morris@morris_lab8 Feb 2023
At last! Happy to share our paper on CellOracle – a computational method for dissecting cell identity via network inference and in silico gene perturbation, led by the amazing @kenjikamimoto68: nature.com/articles/s41586-0…

Dissecting cell identity via network inference and in silico gene perturbation

Nature - A machine-learning-based strategy called CellOracle combines computational perturbation with modelling of gene-regulatory networks to analyse how cell identity is regulated by...

nature.com
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Scientist position in Genomics technology lab at Calico open! It's a unique opportunity for an innovative scientist to study aging across a huge variety of contexts and models with 5 alarm technology. #technology #genomics #aging #singlecell #multiomics calicolabs.com/careers?gh_ji…

Careers - Calico

calicolabs.com
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Wenjun Kong retweeted
clarice@claricehongky16 Aug 2022
We have a new version of this preprint! There are 2 key changes - we now show that scMPRA works in mouse retina (!), and we finally implemented the second U6 transcript to detect unexpressed promoters. Siqi worked really hard on this so please check it out 🙂
clarice@claricehongky12 Nov 2021
Check out the latest preprint from our lab by my dear friend Siqi :) He developed a method to perform MPRAs in single cells and show that it can be used to detect cell-type specific regulation and cell-to-cell variability in cis-regulatory elements! biorxiv.org/content/10.1101/…

A single-cell massively parallel reporter assay detects cell type specific cis-regulatory activity

We developed a single-cell massively parallel reporter assay (scMPRA) to measure the activity of libraries of cis-regulatory sequences (CRSs) across multiple cell-types simultaneously. As a proof of...

biorxiv.org
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We reunited at ISSCR and found @morris_lab “on-site”. @cadyyuheng #ISSCR2022
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Very excited to talk about this collaborative work @morris_lab! We will have Capybara take us on a journey through some interesting biological systems!!
Samantha Morris@morris_lab2 Jun 2022
The Capybara whisperer @WenjunK will be speaking about measuring hybrid cell identity and state transitions in reprogramming (and our new favorite paradigm, hematopoiesis) on Monday!
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Super excited to get hooded by @morris_lab!!! Now we are pros for the attire 😆!
Samantha Morris@morris_lab19 May 2022
Dr. Kong @WenjunK is graduating! We are feeling extra fancy today
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Well, I never expected to write “giant rodent bouncer” in a scientific perspective piece, but here we are. My thoughts on Capybara for cell identity profiling 👇 Congrats @WenjunK @EstebanMazzoni @morris_lab et al! @CellRepMethods @CellStemCell cell.com/cell-reports-method…

Profiling intermediate cell states in high resolution

Kong et al. present Capybara, a computational method to identify cell states from single-cell gene expression data. Notably, Capybara can identify intermediate cell states and cell state transitions,...

cell.com
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Dr. Wenjun Kong (@WenjunK) and a group in the @Morris_Lab developed a new computational tool called Capybara that can measure cell identity and fate transitions. 🔮 #scRNAseq 📎 @CellStemCell | cell.com/cell-stem-cell/full… 🎙️ | bit.ly/3O20q6r
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So mixed feelings watching our dearest capybara finally out in the world. It is still a baby but a strong independent one, built by collaborative forces in the @morris_lab! Hope it grows better with more real world problems! May Capy be treated with gentle, love, and critiques!
Samantha Morris@morris_lab29 Mar 2022
Our latest paper is online @CellStemCell! Capybara: A computational tool to measure cell identity and fate transitions cell.com/cell-stem-cell/full… led by @WenjunK
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Thanks a bunch to everyone who came to my defense today!! It has been a long and amazing journey. And this is truly a lovely and big reveal/surprise! Special thanks and shout out to our amazing PI @morris_lab! I can’t be more fortunate to be a part of this lovely team!
Samantha Morris@morris_lab28 Mar 2022
Congratulations Dr. Kong! @WenjunK
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So happy to share and talk about Capy! Thanks @morris_lab and @Stowers_SRC for the chance to talk about Capy/Colin - Colin is making baby steps to get into the world!
Samantha Morris@morris_lab22 Apr 2021
I have a fantastic transatlantic talk partner in @WenjunK - and thanks for introducing Colin to the world 😂
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I have a fantastic transatlantic talk partner in @WenjunK - and thanks for introducing Colin to the world 😂
Stowers Research Conferences@Stowers_SRC22 Apr 2021
Possibly the very first transatlantic tandem-talk? Great work from SAMANTHA MORRIS and WENJUN KONG (WashU): NEW SINGLE-CELL GENOMIC TECHNOLGIES TO DISSECT AND ENHANCE CELL FATE REPROGRAMMING Colin the Capybara also made a guest appearance. @morris_lab @WenjunK @WUSTLmed
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So excited to see this paper coming out!
Samantha Morris@morris_lab20 Aug 2020
Our latest paper is out @CellStemCell Single-Cell Analysis of Neonatal HSC Ontogeny Reveals Gradual and Uncoordinated Transcriptional Reprogramming that Begins before Birth cell.com/cell-stem-cell/full…
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So happy to be a part of the Morris Lab and love these two preprints! Thanks for everyone in the lab for the amazing support and help! And special thanks to our fearless PI @morris_lab and Cady Fu! Capybara is finally out and I am in happy tears!
Samantha Morris@morris_lab18 Feb 2020
Our latest preprints are up: CellOracle - a tool to dissect cell identity via network inference and in silico gene perturbation, and Capybara - a tool to measure cell identity and fate transitions: biorxiv.org/content/10.1101/…

Capybara: A computational tool to measure cell identity and fate transitions

Transitions in cell identity are fundamental to development, reprogramming, and disease. Single-cell technologies enable the dissection of tissue composition on a cell-by-cell basis in complex...

biorxiv.org
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So happy to be a part of this project and this amazing team! Very excited to see the first software baby I have worked on at @morris_lab to be online 😆
Samantha Morris@morris_lab13 Feb 2020
Our detailed CellTagging protocol is now online @NatureProtocols nature.com/articles/s41596-0…
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Hi, I'm Samantha Morris. 👋 I'm a researcher @WUSTLmed and my lab focuses on reprogramming cell identity to generate cells to repair diseased and damaged organs. Today we take over the official #WashUMed account for #STATMadnessChats!
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Excited to participate in @CellSystemsCP transparent Peer Review process with our (@WenjunK) evaluation of Wu et al.: Comprehending Global and Local Structure of Single-Cell Datasets cell.com/cell-systems/fullte…
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The first paper from our lab is finally out! Single-cell mapping of lineage and identity in direct reprogramming: nature.com/articles/s41586-0… @nature Thread.. (spoiler alert: all our tools, protocols and data are freely available)
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