We are a molecular virology lab led by @samjwilsonphd. ISGs and viruses (SARS-CoV-2, HIV-1, IAVs). https://nitter.gq/t.co/Qyk3CTPkHm
Cambridge, England
Joined January 2017
- Tweets551
- Following393
- Followers2.2K
- Likes1.3K
Pinned Tweet
New @wilsonlabcvr paper. Our work, led by @virologist_atu, showing that the prenylated variant of OAS1 can sense SARS-CoV-2 and protect against severe #COVID19 is out in Science:
science.org/doi/10.1126/scie…
#CVRCovidResponse
🧵 (with some new bits)
Wilson Lab retweeted
Our new paper @JExpMed - Nasal viruses & bacteria are very common in children (90% of symptomatic and ~50% of asymptomatic <5yrs!), and activate nasal defenses, which may have protected from #Covid_19 @YaleMed @Yale_LabMed @YaleIBIO @YalePediatrics
rupress.org/jem/article/221/…
Wilson Lab retweeted
I always say jobs in my lab are great opportunities but this one really is. The last incumbent published 3 1st-author @Nature papers, found a treatment for Covid, and now has a senior job in pharma.
Quantitative geneticists - please consider joining us!
jobs.ac.uk/job/DIL188/postdo….
Wilson Lab retweeted
🔔'Tis the season...to apply for a new job?! My group @MedCambridge is recruiting for 2 posts:
Postdoc: jobs.cam.ac.uk/job/44181/
Research assistant: jobs.cam.ac.uk/job/44250/
Both roles will seek to improve our understanding of coronavirus cross-species transmission. #preparedness
Wilson Lab retweeted
A lovely piece of work that places interferon-mediated antiviral immunity to betacoronaviruses into evolutionary & ecological context.
🚨New paper alert! and it's one I'm really excited for! Resurrection of OAS1 from the ancestor of modern horseshoe bats blocks SARS-CoV-2 replication now out in @PLOSBiology
Here's a 🧵on how we reconstructed an ancient 🦇anti-CoV protein
doi.org/10.1371/journal.pbio…
Wilson Lab retweeted
Really interesting thread and paper about an anti-coronavirus gene in humans that bats lost millions of years ago, which could help explain why bats are such prodigious reservoirs of coronaviruses, posing a constant threat of spillover into humans.
🚨New paper alert! and it's one I'm really excited for! Resurrection of OAS1 from the ancestor of modern horseshoe bats blocks SARS-CoV-2 replication now out in @PLOSBiology
Here's a 🧵on how we reconstructed an ancient 🦇anti-CoV protein
doi.org/10.1371/journal.pbio…
Wilson Lab retweeted
🚨New paper alert! and it's one I'm really excited for! Resurrection of OAS1 from the ancestor of modern horseshoe bats blocks SARS-CoV-2 replication now out in @PLOSBiology
Here's a 🧵on how we reconstructed an ancient 🦇anti-CoV protein
doi.org/10.1371/journal.pbio…
This study builds on our previous work demonstrating human prenylated OAS1 (p46) inhibits SARS-CoV-2 whereas the nonprenylated (p42) form does not.
science.org/doi/10.1126/scie…
The nonprenylated human OAS1 p42 is not functionally analogous to nonprenylated horseshoe bat OAS1.
The paper is explained in this video from @SpyrosLytras
nitter.gq/CVRinfo/status/1729802…
🎥 WATCH | Resurrecting an ancient bat defence against SARS-related coronaviruses - @PLOSBiology
@SpyrosLytras & colleagues predicted and reconstructed the ancient horseshoe bat OAS1 protein, showing it blocks #SARSCoV2 replication.
journals.plos.org/plosbiolog…
New WilsonLabCITIID publication led by @SpyrosLytras where we reconstructed an ancient OAS1 from the ancestor of modern horseshoe bats and demonstrate it possessed anti-SARS-CoV-2 activity.
journals.plos.org/plosbiolog…
Wilson Lab retweeted
One thing the pandemic forever changed for me was my perspective on sharing biomaterials (tools and reagents) from publications. I’ve written about this, with co-author Alexander Harms (@AHarms485), in our new PLOS Biology perspective:
Could better biomaterial sharing improve the scientific community?
@Lab_Rihn_th & @AHarms485 draw on their experiences of sharing #biomaterials to discuss the advantages, challenges, and ways sharing could be more actively promoted and rewarded.
plos.io/3F9HajT
ALT A summary of the benefits and challenges associated with biomaterial sharing. Challenges include administrative burden, time, effort, cost, misuse/misrepresentation, and ethical/intellectual property considerations. Benefits include new ideas/collaborations, improved reproducibility, equity and community, savings in time, money and resources, and maintaining access to materials.
Wilson Lab retweeted
Join our EVIR team in the fight against the Crimean-Congo hemorrhagic fever! We're looking for a Research Assistant to work on #CCHFV. Contact us for more info or to apply!
Wilson Lab retweeted
Please RT. Are you interested in how viruses emerge in humans? We're looking for a postdoctoral investigator to join us and lead exciting projects investigating innate immune barriers to the emergence and pathogenesis of viruses.
jobs.cam.ac.uk/job/42654/
Deadline Oct 1st 2023
We'll be invested in supporting your career and development. If you'd like more info, contact @samjwilsonphd, or read our recent papers:
nature.com/articles/s41586-0…
science.org/doi/10.1126/scie…
Please RT. Are you interested in how viruses emerge in humans? We're looking for a postdoctoral investigator to join us and lead exciting projects investigating innate immune barriers to the emergence and pathogenesis of viruses.
jobs.cam.ac.uk/job/42654/
Deadline Oct 1st 2023
Wilson Lab retweeted
📢 Exciting job opportunity! 📢
A postdoc position is available in our lab at @Dunn_School @UniofOxford to study influenza virus transcription, genome replication, nuclear export and assembly.
More info: my.corehr.com/pls/uoxrecruit…
Wilson Lab retweeted
✨New title unlocked!!✨ Finally a Dr! Big thanks to @katrina_lythgoe and @rbiek for a great viva and ofc to my wonderful supervisors for the past four years @blJOg @SamJWilsonPhD @robertson_lab!! 😁😁🎉🎉
Wilson Lab retweeted
Join us! A postdoc position between my lab and @QuezadaLab has become available at @uclcancer in London. Please help us characterise the molecular mechanisms through which anti-tumour immune responses are controlled.
To apply
ucl.ac.uk/work-at-ucl/search…
Deadline 14 Sept
Please RT!
