I'm almost tired of tweeting cancer progress this year but pancreatic cancer is getting smacked: Two pills, zero chemo, and 18 out of 22 patients saw their tumors shrink Tango paired its pill with daraxonrasib, the RAS pill FDA approved in August after it doubled survival vs chemo (13.2 vs 6.7 months) Most of these patients were already on their THIRD line of treatment, which is usually where the options run out 82% had their tumors shrink. Every single one had the cancer stop growing or shrink. 88% still hadn't progressed at 9 months Main side effects were mouth sores and rash, which compared to pancreatic chemo is kinda a spa day lol Only works on a subtype missing a gene called MTAP(not every pancreatic cancer), and a phase 3 vs chemo starts next year Your grandpa got 6 months and a hospice brochure. Our kids are gonna get two pills and a follow-up scan.