Shawn Carbonell MD PhD šŸ‡µšŸ‡­ | scientist | builder | creative | stealth AI startup šŸ”¬

Seattle, WA
Joined April 2009
So so so grateful for this moment! 🧵 #glioblastoma – at Redondo Beach, CA
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Ordered a @robotaxi from SFO. Got a Model Y with a human driver who farted. So, basically Uber. šŸ’Ø #RoboDutchOven
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Brain Surgery Dropout retweeted
Turns out the future does have flying cars
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Today, we’re launching an ambitious new school called The Horowitz Andreessen Academy. Based in San Francisco, The Academy serves the most promising young high school graduates. We think this can be an elite institution that attracts top tier talent. One that prepares students for the future rather than remaining stuck in the past. The #1 goal is to help students learn to build, which is the most important skill in the AI era. They'll learn primarily by pursuing their own projects, either individually or in groups. There are classes and guest lectures, too, from some truly amazing people who have built modern-day Silicon Valley. The Academy is designed as a network, since that’s the reason students go to school in the first place. Core to that network are our 10 Founding Partners: Anduril, Anthropic, Coinbase, Google, Meta, NVIDIA, OpenAI, Palantir, Replit, and Stripe. The network includes over 50 hiring partners and over 200 speakers and mentors. To join as a hiring partner or faculty member, you can apply on our website. We raised $42M in funding led by @a16z. I'll be CEO and @pmarca and @eriktorenberg will join me on the board. Applications are open for our Founding Class Fellowship, which will be one year and tuition-free. Eventually, pending regulatory approval, we plan to offer a two-year program that charges tuition, similar in cost to an elite private university. We're looking for the most unusually ambitious young builders on the planet. Come join us in San Francisco: theacademysf.com/
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52 hours in NYC āš”ļø Had a fantastic evening at the TIME100 Health Leadership Forum. Thank you @TIME @TIMEHealth for the invitation. šŸ™šŸ½
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Brain Surgery Dropout retweeted
I always say this to people when they ask me about pickleball: Super Bowl I did not sell out its stadium. The NBA Finals was so small in the beginning relative to what it has become, and at least once, CBS chose to air golf instead, so it put the NBA game on tape delay. UFC was banned in most states in this country within a lot of our lifetimes. That’s the journey of things becoming popular. Every sport that’s massive today was small and easy to dismiss at some point. I’m 50 years old. I’ve watched UFC go from a side circus to one of the most important sports in the world. In my lifetime, I watched basketball go from the third sport to potentially the first sport, or the second sport. I watched football pass baseball as most peoples’ favorite sport in the U.S. I saw Tiger Woods change the calculus on golf. I watched ESPN go from something very few people watched when I was a kid to a cultural phenomenon. That history matters because I think people dramatically underestimate how much room there is for more sports, pickleball and wiffle ball included.
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a privilege to finally see this in person šŸ™šŸ½
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Brain Surgery Dropout retweeted
I turn 50 today. This is a message to my kids but I offer it to you in case any of it rings useful. I was born in Sri Lanka in 1976 in a country that, at the time, was about to enter a decades long civil war. My father was able to get stationed at the Sri Lankan High Commission in Canada for four years in the early 80s - when some of the fighting was most severe - and which from our vantage point in Canada gave us some respite from an otherwise omnipresent conflict. He came as a diplomat but then my father filed for refugee status after four years when his life was threatened by militants. We stayed in Canada as refugees. My dad never really landed on his feet and we grew up on welfare. My mom stepped up. She did an incredible thing and put our family on her back and kept marching forward. Sometimes the steps were very small but she always tried to keep moving forward. I worked at Burger King starting at 14, giving my paycheck to my mom and dad to support our family in the role that I was assigned - earn enough to pay for our bus passes because we couldn’t afford a car. I was a loser growing up. Some friends, some good memories but mostly forgettable and lonely. I wasn’t very studious but did get my act together in my final year and got into a great university. I immigrated to the US soon after graduating and found an opportunity. Things clicked and I have been traveling a path to find myself ever since. Only in America is this possible… I worked hard, followed the rules, paid my taxes and stayed in California out of loyalty for the opportunities it has given me despite its dysfunction. I found my wife here. Had my kids here. Found my tribe here. There have been some very hard times as well - deaths, divorce, financial pain, mistakes of omission and mistakes of commission. You can’t dwell on these things - they are weights that will pull you down if you’re not careful. Learn from them. Respect them. BUT MOVE ON. To think 50 years ago I could have ever gotten a chance to meet the people I’ve met and have had the experiences I’ve had would have been mind boggling to my parents. It’s mind boggling to me now. We forget often and try to convince others it’s not true but America truly is the best country in the world. Everything and anything is possible here. I can testify. Be grateful to be here. This is the only place that gives EVERYONE a chance to live a great adventure. The first 50 years have been that for me - an incredible adventure. Notice there is nothing here about accomplishments or money. Because it doesn’t matter and it won’t matter. You will be dust in less than 100 years from now and the decision to be remembered won’t be yours so stop sweating it. It’s not in your control. So what is in your control? Be kind. Have fun. Work on something meaningful to you. Find your tribe. Try to find perspective. Find an incredible partner. Have a bunch of kids. Live an adventure. Forgive your parents - they were doing the best they could even if that wasn’t what you deserved. I will do what I can to make my next 50 years a wild ride. You should too. I love you and thank you. ā¤ļø šŸ™šŸ½šŸ™šŸ½
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this is my sign to finally try @cursor_ai 🄹
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Brain Surgery Dropout retweeted
We're hiring! We're looking for hardworking electrical engineers who want to disrupt the MRI industry. This is a growth role in our Menlo Park, California office. You'll work, and grow, alongside us as we push towards making meaningful progress every single day. If you're an awesome electrical engineer, apply. If you've personally felt the delays and costs of MRI, apply. If you want to change that, apply. adialante.com/careers
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farewell tokens 🄹
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Brain Surgery Dropout retweeted
GPT-5.6 sol launches thursday! happy building
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if your podcast doesn’t mention phrases like ā€œā€¦eigenvalues for random Hermitian matricesā€¦ā€ what are you even doing bro? šŸ™„ @dwarkeshpodcast
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here’s to the solo founder AI vampires among us āœØšŸ§›šŸ½āœØ open.substack.com/pub/speedr…
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claude fable is an honest name bc its biology capabilities are fictional 🄹
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[written with claude fable 5 bc it’s otherwise useless to me 🫩]
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I had lots of sex with my cofounder. šŸ”„
Co-founder is marriage without the sex.
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[we were married before we became cofounders] 🄱
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I was on like slide THREE and she started scrolling 😭 Major biotech VC. She was an associate, the partner didn’t bother showing up lol.
If a VC is on their phone, looking bored while you're pitching Cut the meeting short. I wish I had done that every time. It never led anywhere, and you have better things to do.
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$25M just to PREPARE an IND??!?! That’s nuts. We FINISHED Phase I for less. Fun episode tho, enjoyed the format.
NEW podcast episode is up! "Tim’s Founder Kitchen — From Brainstorm to The President’s Office in Two Months (Featuring Jake Becraft, Strand Therapeutics)" This episode is an experiment! I'm trying out a new format: half interview, half live jam session. I've started a new series, working title "Tim's Founder Kitchen," built around actual brainstorming sessions with founders willing to share the audio. This first instalment is with Jake Becraft of Strand Therapeutics. @DrSynbio is the CEO and co-founder of @StrandTx, a clinical-stage biotechnology company with a pipeline of breakthrough mRNA therapeutics for cancers and autoimmune diseases. Let me know by replying here what you think of this experiment and how I can make the series better. Please enjoy!
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