Cathrin Grawe (@c_grawe) profile picture

Cathrin Grawe

@c_grawe

PhD candidate @LabVermeulen, @Radboud_Uni & @RIMLSInstitute

 Nijmegen
Joined April 2020
  • Tweets23
  • Following153
  • Followers54
5Media
Photo by Cathrin Grawe (@c_grawe)Photo by Cathrin Grawe (@c_grawe)Photo by Cathrin Grawe (@c_grawe)Photo by Cathrin Grawe (@c_grawe)Photo by Cathrin Grawe (@c_grawe)
Great work from Cathrin Grawe and others in our lab!
MVermeulenLab (@LabVermeulen) profile pictureMVermeulenLab@LabVermeulen29 Jul 2023
Check out our latest publication in which we present PASMAN to profile DNA-protein affinities and specificities from crude lysates using a SILAC/TMT multiplexed quantification approach. 20 DNA affinity purifications analyzed in a single LC-MS run! pubs.acs.org/doi/10.1021/acs…
Determining DNA–Protein Binding Affinities and Specificities from Crude Lysates Using a Combined...

Determining DNA–Protein Binding Affinities and Specificities from Crude Lysates Using a Combined...

Abstract. In recent years, quantitative mass spectrometry-based interaction proteomics technology has proven very useful in identifying specific DNA–protei

pubs.acs.org
3
6
1,680
📢Paper alert! Excited to share our latest work from @LabVermeulen, out now at @NAR_Open doi.org/10.1093/nar/gkac1236. Highlights in a thread below: (1/7)

ONECUT2 regulates RANKL-dependent enterocyte and microfold cell differentiation in the small...

Abstract. Microfold (M) cells reside in the intestinal epithelium of Peyer's patches (PP). Their unique ability to take up and transport antigens from the

academic.oup.com
1
5
2
16
2,003
Congratulations to all authors on a great piece of work! @c_grawe from our lab performed DNA affinity purifications for this collaboration! 👍
Eric Kalkhoven (@EKalkhoven) profile pictureEric Kalkhoven@EKalkhoven30 Nov 2022
⁦Our study on PPARgamma mutants is published! Great collaborative effort with the Mandrup lab ⁦@susmandrup⁩ and many others! nature.com/articles/s41467-0…
2
3
Had a great time at #IMSC2022 . Very grateful that I had the opportunity to present my work during a great session chaired by Kathryn Lilley @lilley_ks and Garry Corthals @g_in_t
Image from Cathrin Grawe (@c_grawe)
8
👇check out this exciting post-doc opportunity in our lab to work in a consortium dedicated to the function of non-coding mutations in cancer! @oncodeinstitute
RIMLS-Science (@RIMLS_Science) profile pictureRIMLS-Science@RIMLS_Science22 Dec 2021
There is a postdoc position available in the @LabVermeulen! Apply ⬇️
10
1
8
Cathrin Grawe retweeted
Ralph Grand (@RalphSGrand) profile picture
Ralph Grand@RalphSGrand30 Nov 2021
The GrandLab will open soon and is looking for its pioneering team. Two PhD positions are available to study the regulation of cellular essential genes in mammalian cells. Please apply by the 31.12.2021: zmbh.uni-heidelberg.de/Grand…
4
42
2
75
Excited to see our PAQMAN method being applied to study PTM-protein interactions beyond nucleic acid-protein interactions. Check @kw_kliza paper for more information👇
Katarzyna Kliza (@kw_kliza) profile pictureKatarzyna Kliza@kw_kliza21 Sep 2021
Excited to share my postdoc work @LabVermeulen out in @MolecularCell! We combined chemical synthesis of affinity-enrichment ADPr probes with proteomics to identify and discriminate between MAR and PAR readers. A fruitful collaboration with Filippov lab! cell.com/molecular-cell/full…
Reading ADP-ribosylation signaling using chemical biology and interaction proteomics

Reading ADP-ribosylation signaling using chemical biology and interaction proteomics

Kliza et al. synthesized biotinylated ADPr probes and used them as affinity-purification reagents to identify proteome-wide MAR and PAR readers. They also determined apparent binding affinities for...

cell.com
2
6
Post-doc position available (stem cell proteomics), please RT! 👇Have a good weekend! ru.nl/werken-bij/vacature/de…
18
2
20
Check out our latest paper in which we developed a new 'off the shelf' proximity biotinylation enzyme, called ProtA-Turbo, that facilitates proximity biotinylation experiments without the need for genetic manipulation of target cells. nature.com/articles/s41467-0…
6
46
5
169
👇👍😀
Trends in Biotechnology (@TrendsinBiotech) profile pictureTrends in Biotechnology@TrendsinBiotech11 Aug 2021
Our September issue is online! Synthetic DNA (@hollfelderlab), RNA-protein interactions (@LabVermeulen), Nicotiana metabolic engineering (@GoossensLabVIB), artificial cell biosensors (@NehaPKamat), microbial nanowires (@microbeelectric) and more: cell.com/trends/biotechnolog…
Image from Trends in Biotechnology (@TrendsinBiotech)
1
7
Excited to share our collaborative work that has been published in @Nature! We identified Banp, a long-sought after transcription factor that binds the CGCG motif. With @SchubelerLab, @LabVermeulen and @LabThoma. nature.com/articles/s41586-0…

BANP opens chromatin and activates CpG-island-regulated genes

Nature - BANP is identified as the transcription factor that binds the CGCG element in a DNA-methylation-dependent manner, opens chromatin and activates a class of essential CpG-island-regulated...

nature.com
6
42
Very interesting to see how electroporation cuvettes are shipped nowadays🤔😂🍟 Unfortunately, no chips included but I would pass on the beef dripping anyway...
Image from Cathrin Grawe (@c_grawe)
4
Our attempt to analyse mass spec data with Python 🙃 @Suz_Stelloo
1
2
1
5
Very proud to present our review article, where we discuss methods to study RNA-protein interactions with a focus on recently developed Cas13-based approaches. A good end of this chaotic year and a nice start of the holidays :D
MVermeulenLab (@LabVermeulen) profile pictureMVermeulenLab@LabVermeulen20 Dec 2020
Check out our latest review on proteomics methods to study RNA-protein interactions. Fantastic work from Cathrin Gräwe (@c_grawe), Suzan Stelloo (@Suz_Stelloo) and Femke van Hout! Happy holidays everyone! cell.com/trends/biotechnolog…

RNA-Centric Methods: Toward the Interactome of Specific RNA Transcripts

RNA–protein interactions play an important role in numerous cellular processes in health and disease. In recent years, the global RNA-bound proteome has been extensively studied, uncovering many...

cell.com
1
13
I had the honour to attend the opening of the academic year today @Radboud_Uni . I enjoyed it a lot :)
Image from Cathrin Grawe (@c_grawe)
4
Tune in on Tuesday @ 04:30 UK time to hear the latest from our lab including unpublished data on a novel essential mammalian transcription factor that activates CpG islands and positions nucleosomes (also DNA methylation involved)
@qmulepigenetics (@QMULepigenetics) profile picture@qmulepigenetics@QMULepigenetics9 Jul 2020
Our next webinar is on Tuesday, 14th at 4.30pm BST. Dirk Schübeler (@SchubelerLab) will be talking about the interplay between transcription factors and chromatin. Zoom link is at qmulepigenetics.com/webinars. Thanks to @Diagenode for the support.
Image from @qmulepigenetics (@QMULepigenetics)
1
22
1
93
Cathrin Grawe retweeted
chet loh (@chetloh) profile picture
chet loh@chetloh8 Jul 2020
Proud to present our work, highlighting the priming of lineage choice during embryoid body differentiation in the absence of different PRC2 subunits. @MatteoPerino_ @GJCVeenstra biorxiv.org/content/10.1101/…
Loss of PRC2 subunits primes lineage choice during exit of pluripotency

Loss of PRC2 subunits primes lineage choice during exit of pluripotency

Polycomb Repressive Complex 2 (PRC2) is crucial for the coordinated expression of genes during early embryonic development, catalyzing histone H3 lysine 27 trimethylation. There are two distinct PRC2...

biorxiv.org
1
10
4
25
Finding this dividing T-cell under the microscope is the brightside of a failed experiment 🧐🙃
Image from Cathrin Grawe (@c_grawe)
2
Cathrin Grawe retweeted
MVermeulenLab (@LabVermeulen) profile picture
MVermeulenLab@LabVermeulen2 Jun 2020
Another great cancer genomics and proteomics collaboration with the lab of Kevin Brown and others! Great work from Matthew Makowski and Cathrin Grawe in our lab! nature.com/articles/s41467-0…
Massively parallel reporter assays of melanoma risk variants identify MX2 as a gene promoting...

Massively parallel reporter assays of melanoma risk variants identify MX2 as a gene promoting...

Nature Communications - There are more than 20 known melanoma susceptibility genes. Here, using a massively parallel reporter assay, the authors identify risk-associated variants that alter gene...

nature.com
4
13
Load more