@ckpfaller

Senior Associate Consultant II and Scientific Director of ABSL3 lab Dept. of Molecular Medicine, Mayo Clinic

 Rochester, MN, United States
Joined August 2016
  • Tweets163
  • Following144
  • Followers127
5Media
Shout out to Oliver Siering from my lab for this piece of work! From sequence analysis to in vivo evaluation. Thank you @JVirology for the editorial spotlight! @PEI_Germany @ASMicrobiology @GesVirologie @ASVPresident
JVirology Editors@JVirology31 Jan 2021
#JVirology SPOTLIGHT from Pfaller lab! Morbillivirus accessory C protein, which prevents production of double-stranded viral RNAs that stimulate innate immunity and activate interferon production, is essential for canine distemper virus pathogenesis bit.ly/3oBPjTu
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Christian Pfaller retweeted
Duke Neurosurgery@Dukeneurosurg5 Mar 2025
Continuing our countdown to #InternationalWomensDay ! 3 questions. 3 answers. 1 inspiring Duke brain tumor researcher: Here's Kathy Ayasoufi, PhD (@KAyasoufi). 💡🧠✨ #WomenInNeurosurgery #iwd #brainpower #braintumor
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New pre-print from my lab at @PEI_Germany and @MayoClinic. TSniffer: Unbiased de novo identification of RNA editing sites and quantification of editing activity in RNA-seq data biorxiv.org/content/10.1101/…

TSniffer: Unbiased de novo identification of RNA editing sites and quantification of editing...

RNA editing by adenosine deaminases acting on RNA (ADARs) is an evolutionarily conserved posttranscriptional modification essential for organismal development and normal cell function. Three cataly...

biorxiv.org
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Outstanding work by Maike Herrmann, who has developed the most advanced algorithm to detect and quantify RNA editing sites by ADARs.
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Christian Pfaller retweeted
Katayoun Ayasoufi@KAyasoufi5 Jul 2022
I'll be giving a talk on brain resident memory T cell responses during viral infections on July 14th ! Join us!
Open Box Science@OpenBoxSci5 Jul 2022
OBS Seminar: "#Neuroimmunology: T cell-#brain interactions " ⏰11 AM ET, Thu, July 14 📢 Speakers Luming Zhou @sdigiovanni3 @uclnpp & @KAyasoufi @DrAaronJJohnson @Cori_Fain @MayoClinic 📢 Moderator @yajing_xu @IcahnMountSinai 👉Registration us02web.zoom.us/meeting/regi… #OpenScience
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Christian Pfaller retweeted
Katayoun Ayasoufi@KAyasoufi10 Apr 2022
Very excited to share our newest preprint from @DrAaronJJohnson lab! In this study, we demonstrate that the naive mouse brain has T cells in the tissue itself and that these T cells are not in or close to the vasculature and have a resident memory phenotype.
bioRxiv Immunology@biorxiv_immuno10 Apr 2022
Brain resident memory T cells rapidly expand and initiate neuroinflammatory responses following CNS injury and viral infection biorxiv.org/cgi/content/shor… #biorxiv_immuno
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Christian Pfaller retweeted
Katayoun Ayasoufi@KAyasoufi25 Nov 2021
So thankful to be spending this Thanksgiving with my amazing family with my parents and wonderful brother @AliAyaSoufi and awesome husband @ckpfaller . Turkey and photo credit to my brother. ❤❤❤❤❤
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Fühlen Sie sich eigentlich angesprochen, wenn entgegensetze, dass dies eine "Pandemie der DUMPFBACKEN" ist @SWagenknecht ? Ab wann müssen Politiker eigentlich zum TüV?
Jan Hartmann
@pelagicbird12 Nov 2021
Kurzer Faktencheck zum gerade veröffentlichten Meinungsartikel von Sahra #Wagenknecht in der @welt mit dem gegen Massnahmen zur Erhöhung der #Impfquote Stimmung gemacht werden soll.
When you're on the train and people have endless debates who and where and at which point of the journey they have to wear FFP2 masks...😷 thank you @DB_Bahn and @BMG_Bund
Christian Pfaller retweeted
Christian Drosten
@c_drosten3 Nov 2021
Impfquoten in D und UK sind ungefähr gleich. UK hat aber viel mehr Genesene (und Verstorbene). Eine Beruhigung in UK rückt nun langsam in Reichweite. Dies zu erreichen würde uns wohl eine ähnliche Zahl an Verstorbenen kosten. Einzige Alternative ist das Schließen der Impflücke.
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Christian Pfaller retweeted
Weitzman Lab@WeitzmanLab22 Oct 2021
CHOP/Penn are now accepting applications for our postdoc program to promote academic diversity and my lab has open positions. Please RT and come join us research.upenn.edu/postdocs-…

Provost’s Fellowship - Office of Postdoctoral Affairs

The Provost’s Postdoctoral Fellowship is part of our ongoing efforts to enhance training opportunties in research at the University of Pennsylvania.

postdocs.upenn.edu
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We are looking for an enthusiastic, virus-loving PhD student, who would like to learn more about morbilliviruses and how they are affected by the immune system. Apply, if you are interested, or forward to anyone who might be. @SFB_1021 @GesVirologie @PEI_Germany @dfg_public
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Entwicklung zukünftiger #Gentherapien im immuntherapeutischen Bereich: Wissenschaftler:innnen des Paul-Ehrlich-Instituts haben neue Genfähren für den gezielten Gentransfer in T-Lymphozythen der Maus entwickelt. 👉 ow.ly/YLNQ50GqMM6
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Christian Pfaller retweeted
Conzelmann Lab@ConzelmannLab14 Oct 2021
Lentiviral and adeno-associated vectors efficiently transduce mouse T ... sciencedirect.com/science/ar…
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Our study testing efficacy of a #measles #virus inhibitor in non-human primates is out in @NatureComms. Congrats @Kevin_Wittwer and all co-authors! rdcu.be/cxkMO
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nature.com/articles/s41467-0… was supported by @SFB_1021 @dfg_public and @PEI_Germany

Small-molecule polymerase inhibitor protects non-human primates from measles and reduces shedding

Nature Communications - Measles virus is highly contagious and outbreaks occur worldwide. Here the authors show that the orally bioavailable small-molecule polymerase inhibitor ERDRP-0519 prevents...

nature.com
Christian Pfaller retweeted
König Lab@konig_lab11 Sep 2021
check our our latest print! #SAMHD1, #CancerResearch rdcu.be/cxAhw
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ERDRP0519 may be an option to support our efforts to eradicate #measles through #vaccination. ERDRP0519 could be used to protect those who cannot receive the vaccine for health reasons. It may also help break transmission chains in local measles outbreaks.
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However, #vaccination remains our only shot to eradicate #measles completely and prevent suffering and dying of children worldwide.
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