Hannover | 28 | MD | Physician🩺 | Scientist🦠🧬🔬
CiiM
Joined April 2015
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- Following184
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Honored to receive this year’s Carl Anton Ewald award by the German Society for Gastroenterology, Digestive and Metabolic Diseases.
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Happy to receive this year’s doctoral thesis award of the Northern German Association of Gastroenterologists (NDGG)🩺🧪🎓🎉
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Happy to see some of our recent findings now published in JVH📚.
🔬We show how soluble immune mediators are expressed when two
🦠chronic viral infections meet each other in a human host and how they are affected when
💪 viral dominance comes into play.
doi.org/10.1111/jvh.70092
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The exact mechanisms behind the interplay of both viruses remain elusive and need further investigation.
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We now demonstrate that HBV activity seems to play a major role in this condition, regardless of the usual consideration as a stealth virus. HBV activity was in our study associated with higher expression of soluble immune mediators.
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It has been shown before that coinfection expresses different dominance patterns with HBV and/or HCV being the dominant infections.
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It is rare to be able to study two chronic infections in a human host at the same time. HBV/HCV is still vastly understudied and information limited.
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HBV and HCV coinfection is a rare condition, especially prevalent in high risk groups for infection. It goes along with an even higher cirrhosis risk than each mono infection on its own.
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Carlos Oltmanns retweeted
This years research group retreat in collaboration with @labCornbergKraf featured:
- 10 research presentations🩺
- progress reports on our prospective studies📈
- countless discussions & ideas💡
- sunset BBQ ☀️
- Power Point karaoke 🥳
Some impressions below #livertwitter
Carlos Oltmanns retweeted
Today it was time for the last nails during the topping-out ceremony of CiiM, a joint initiative of @helmholtz_hzi and @MHH_life, realized with funds from @BMBF_Bund, Lower Saxony's Minister for Science and Culture (MWK) and @helmholtz_de.
Carlos Oltmanns retweeted
Had a great time in #Milano at #EASL2024 presenting our newest data about the soluble inflammatory mileu in chronic HCV patients developing HCC
#HCC #HCV #Inflammation
Carlos Oltmanns retweeted
#EASL2024 was an absolute blast! 🥳 Thanks so much for having us and for the amazing opportunity to present our research in #viralhepatitis 👩🔬👨🔬
Great day to have a poster presentation @EASLnews Congress 2024:
Shared our recent data on HBV/HCV coinfection🦠🩺🔬🖥️
-Inflammatory cytokine milieu was associated with HBV activity in our retrospective cohort study
-Altered Cytokines were linked to fibrosis and carcinogenesis
🦠🔬 S2-bound α1-acid glycoprotein a promising marker to predict HCC after HCV cure? Results from our recent phase 3 bio marker trial @MHH_life in collaboration with @liu_universitet & @karolinskainst
doi.org/10.1111/jvh.13943
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💊Treatment of HCV led to a decrease of S2-bound AGP. Additionally, S2-bound AGP levels were associated with liver fibrosis and inflammation. Patients with chronic hepatitis B virus infection and metabolically associated steatotic liver disease showed low levels of S2-bound AGP.
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