Associate Professor, University of Southern California, @ostrowusc, @uscnorris, GI and oral cancer, gene regulation, epigenomics
Los Angeles
Joined September 2017
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De-Chen Lin retweeted
Dr. De-Chen Lin will co-host the FASEB Catalyst Conference: Tumor Organoid Modeling in Cancer Biology, which will be held virtually on November 4. Visit the link for more information and to register for this free event. #CancerResearch #Organoids
faseb.org/meetings-and-event…
Excited to co-organize the upcoming FASEB Catalyst Conference: Tumor Organoid Modeling in Cancer Biology on Nov 4!
Free virtual meeting — register here:
us06web.zoom.us/webinar/regi…
@FASEBorg #Organoids #CancerResearch #TumorOrganoids
🤖 Made with AI
Great trip to Kyoto for the AACR-JCA meeting. Wonderful to see old friends and make new ones. Thank you to @AACR and outgoing AACR president @lillian_siu for the invitation to speak on our work advancing liquid biopsy - and the late night yakitori, chicken hearts, liver and all.
Congrats Linghua!
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great work Dan! Huge congrats!
A whole genome sequencing assay named HPV-DeepSeek sniffs out signs of residual disease after surgery in patients with #HPV+ head and neck cancer, and detects recurrence earlier than digital PCR and standard clinical criteria. @FadenLab @BIDharvardOHNS scim.ag/3S52VLF
Thank you!
Congrats to Dr. Dechen Lin on his promotion to Associate Professor of Biomedical Sciences at @ostrowusc.
A leader in cancer genomics & epigenomics, his work uses advanced genomics and organoid models to uncover how cancers progress, evade immunity, and respond to therapy.
ALT Headshot of Dr. Dechen Lin.
Congratulations Linghua!!!
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De-Chen Lin retweeted
“fastVEP annotates the complete GIAB HG002 clinical whole-genome sequencing benchmark (4.05 million high-confidence variants) against the full Ensembl GRCh38 gene model (508,530 transcripts) in 86 seconds.”
Finally! VEP is usable.
fastVEP: A Fast, Comprehensive Variant Effect Predictor Written in Rust biorxiv.org/content/10.64898… #biorxiv_genomic
De-Chen Lin retweeted
CCMB would like to congratulate Dr. Dechen Lin on his promotion to Associate Professor of Biomedical Sciences at the Herman Ostrow School of Dentistry of USC! #CCMBUSC #USCResearch #Promotion #CancerResearch
De-Chen Lin retweeted
🧬Cutting-Edge Advances in Cancer Immunology and Immunotherapy: From Basic Science to Clinical Impact
Join us for a full-day workshop at @USC on 8 May 2026 — featuring an outstanding lineup of experts.
Register for free📌:
forms.office.com/e/XZweVunq2…
Linghua is unstoppable!
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A pleasure to contribute to @NatureGenet commentary discussing advances in squamous cancer genomics and TME crosstalk, highlighting how integrated single-cell and spatial analyses are reshaping our understanding of cancer evolution.
🔗 nature.com/articles/s41588-0…
Congratulations, Sid! 🎉 An incredible milestone and so well deserved. Your leadership, vision, and collaborative spirit will no doubt take @WashUMedENT to new heights! 👏👏 #ENT #Leadership #Innovation
Very excited to serve as the next Chair/Dept Head @WashUMedENT!! I am truly humbled to lead this storied department and push it higher through collaboration, persistence, and innovation with our incredible faculty/staff as we advance care of #ENT patients. medicine.washu.edu/news/pura…
anything from @anand_mt's lab is golden! Please give it a try!
De-Chen Lin retweeted
Introducing Grabstract. An AI tool that transforms your research texts into visuals.
Please retweet and share 🙏
Introducing grabstract: Transform complex scientific texts into clear, visual insights
Just paste your abstract to create:
📊 Graphical abstracts
🖼️ Scientific posters
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Try it for free: grabstract.io
#AcademicTwitter #SciComm
Honored to share my commentary in @CellStemCell “Unmasking Cancer’s Hidden Nerve Route with Patient-Derived Organoids” 🧠🧬
A must read from the groups of Suet Yi Leung and Alan S.L. Wong from University of Hong Kong
👉
sciencedirect.com/science/ar…
🔬 New in JEM: Our team uncovered that early MLL3 mutations fuel UASCC growth—but also boost immune response when intact. High MLL3 = better immunotherapy outcomes. A new path for treatment. see below👇👇👇
Upper aerodigestive squamous cell carcinoma (UASCC) is a tough cancer to treat because it grows aggressively. Published in the Journal of Experimental Medicine, USC Norris member Dr. Dechen Lin, assistant professor for the Herman Ostrow School of Dentistry, and his colleagues, revealed that the gene MLL3 plays a key role in how upper aerodigestive squamous cell carcinoma begins, grows, and responds to treatment. The data revealed that MLL3 mutations occur early and can drive cancer development. MLL3 teams up with GRHL2 to help the immune system fight tumors, and higher MLL3 levels = better response to immunotherapy. These insights open the door to new treatment strategies, giving patients more ways to fight back. Read the full publication here: rupress.org/jem/article-abst….
Congrats Ryan!!
Excited to share our study led by fellow Lawrence Wu, focusing on the molecular characterization of early-onset esophagogastric cancer. We explore transcriptional profiles, immune microenvironment, and real-world survival outcomes.
rdcu.be/ewEsO
Congrats @FadenLab Very important work!
A new liquid biopsy blood test could help detect cases of human papillomavirus (HPV)-associated head and neck cancers. The test has the potential to be significantly more accurate than current methods, including before symptoms develop, according to new Mass General Brigham research led by Daniel Faden, MD, FACS. spklr.io/6019hCvv
