Dan Nasko retweeted
I'm happy to see sawfish now available for the community to use. Sawfish is another step towards high accuracy and consistent SV genotyping. Great work by Chris Saunders and many others.
Happy to introduce sawfish, a new HiFi structural variant caller emphasizing local haplotype modeling to improve SV representation and genotyping in both single and joint-sample analysis contexts: 1/n
doi.org/10.1101/2024.08.19.6…
Dan Nasko retweeted
The platinum pedigree genome - four generations, near T2T phased assemblies, multiple technologies including @PacBio HiFi. Here's your new "truth" set!!
biorxiv.org/content/10.1101/…
Dan Nasko retweeted
Short-read #sequencing with #Onso continues to push the boundaries of genomic discoveries across diverse fields of research.
Explore how the Onso Q40+ accuracy is unlocking new levels of precision and certainty in oncology, public health, and beyond. bit.ly/3ztRTpK
Dan Nasko retweeted
Considering a short-read upgrade?
Vote: What's the most compelling feature of the #Onso system for your research? See how Onso can boost your research and grab our exclusive trade-in offer. T&Cs apply.
Details: bit.ly/4bSFmtL
#PacBio
42%Up to 15× higher accuracy
26%Less sequencing needed
11%Reach difficult regions
21%Seamless integration
19 votes • Final results Dan Nasko retweeted
long reads: Lightweight taxonomic profiling of long-read sequenced metagenomes with Lemur and Magnet dlvr.it/T8TZ2X
Dan Nasko retweeted
Come see @dnasko speak at the @ZymoResearch booth on the fecal reference #longread #metagenome project on Sat from 2:40-3pm and then stick around for the presentations in the @PacBio booth next door #933 from 3-4! And we have talks at the same time Friday too and prize drawings.
Master the Microbiome with informative in-booth talks from Zymo Research's experts and esteemed collaborators at ASM Microbe! Join us at booth #1033 this Friday and Saturday for engaging discussions on #SamplePrep, #Standards, #Metagenomics, #Bioinformatics, & more. See you soon!
Dan Nasko retweeted
Our #microbiome SMRT Grant just opened. Apply if you'd like!
We're looking for #longread projects for full-length #16S, shotgun #metagenome read-based profiling, or metagenome assembly/MAGs + @PhaseGenomics ProxiMeta Hi-C with lib prep and seq at @ZymoResearch and @SeqCenter.
Discover new possibilities with accurate long-read sequencing at scale.
Apply for the #PacBio 2024 Microbial Genomics SMRT Grant. Tell us in 100 words or less how HiFi sequencing will advance your #metagenomics research to win free sequencing!
Details: bit.ly/3z89XFJ
Dan Nasko retweeted
Low input? Low frequency variants? Low cost? Get it all with the PacBio Onso system and our PacBio Compatible partner @idtdna's xGen high-conversion NGS library prep.
See the data here:
Dataset: bit.ly/4aOho2e
Tech note: bit.ly/4aKvWQj
#PacBio #ESHG2024
Dan Nasko retweeted
Our new pre-print is live! 🧬🦠🎉
We performed a deep-sequencing experiment using @PacBio HiFi reads (Revio & Sequel IIe) on a pooled human gut reference from @ZymoResearch, with a primary focus on #metagenome assembly.
1/6
doi.org/10.1101/2024.05.10.5…
Dan Nasko retweeted
Fantastic review of #metagenomics with long read sequencing, including @PacBio HiFi; many advances covered.
Strong conclusion:
"long-read sequencing has firmly established its
position and is poised to revolutionize another frontier in life sciences with unwavering potential" 🎉
Review paper out today @naturemethods on long-read #sequencing for #metagenomic: rdcu.be/dGeIj Great advancements on utility of @nanopore @PacBio forming novel insights in diversity and resolution. Great work by @D_Agustinho @fuyvei96 @traingene
@BCM_HGSC @RiceCompSci
Dan Nasko retweeted
We’ve graduated HiFiCNV to 1.0 to recognize that it’s now a stable part of our HiFi WGS toolchain -- to celebrate we’ve added a few quality-of-life and error-handling improvements. Find more details on our latest github release here:
github.com/PacificBioscience…
Dan Nasko retweeted
Happy that our manuscript describing TRGT is now available. If you would like to learn more about the importance of tandem repeats and the variation that must be measured when studying them, please also check out the accompanying research briefing: nature.com/articles/s41587-0…
Dan Nasko retweeted
Characterization and visualization of tandem repeats at genome scale go.nature.com/3TKX7FF
Dan Nasko retweeted
Live from #ISLB23 in Madrid!
"High Sensitivity Detection of Specific Ultra Low-Frequency Somatic Mutations for Minimal Residual Disease (MRD) Monitoring" See the data fresh from @PacBio's Onso platform with @tingfordha! #liquidbiopsy
Dan Nasko retweeted
The first #Onso short-read sequencing system has left the building!
Featuring exceptional SBB chemistry, it unlocks the promise of groundbreaking discovery in #oncology, disease research, and beyond. Stay tuned to see what Q40+ accuracy can do. pacb.com/press_releases/pacb…
#PacBio
Dan Nasko retweeted
Improved understanding of biorisk for research involving microbial modification using annotated sequences of concern frontiersin.org/articles/10.…
Dan Nasko retweeted
The CINEMA Paris registration deadline is fast approaching (April 28th) and we are now down to the final few spots.
Register today to save your spot to attend this🆓workshop to hear from leading experts in metagenomic analysis in Paris this July! 🇫🇷
🔜events.rice.edu/event/345710…
The Rice Global Paris Center will host Rice researchers Todd Treangen & Lauren Stadler & the CINEMA Metagenome Analysis Workshop in July.
The event, held in Paris' historic Marais district, brings together world-class experts.
Tuition is now free! cs.rice.edu/cinema
