
Computational Biologist. I use computers and stats to help answer difficult biological questions. Assistant Professor at @IcahnMountSinai
Manhattan, NY
Joined August 2013
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Another beautiful study from our research team composed of several laboratories spanning pathology, neuropsychiatry and immunology. nature.com/articles/s41467-0… @NatureComms @IcahnMountSinai
First time participating on AAEV. I'm super excited! aaev.org/2026-newyork #extracellularvesicles #vesicles #AAEV
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How To Choose a Good Scientific Problem
cell.com/molecular-cell/full… via @UriAlonWeizmann
Edgar Gonzalez-Kozlova retweeted
It's f*cking wild: Google, Cloudflare, Obsidian's CEO and the guy building Claude Code all put their AI configs on GitHub for free, and most people are still starting from zero
1. Matt Pocock's skills · 318K stars
18M+ installs. the exact folder of AI instructions he uses every day: tests first, clear specs, real reviews
github.com/mattpocock/skills
2. Addy Osmani's skills · 92K stars
engineering skills from the guy working on Claude Code at Anthropic
github.com/addyosmani/agent-…
3. Cloudflare's audit · 63.9K stars
the starting point of what now scans 128 of Cloudflare's own repos. one team of agents hunts for bugs, another tries to prove them wrong
github.com/cloudflare/securi…
4. Obsidian CEO's skills · 51K stars
teaches any AI to write real Obsidian notes instead of messy text
github.com/kepano/obsidian-s…
5. Google's goldfish · 14.8K stars
2 weeks old. the plugin Google's own engineers use to catch AI coding mistakes. the agent writes a design doc, then fresh AI sessions that never saw it try to tear it apart
github.com/google/elephant-g…
the biggest teams in tech already stopped writing prompts from zero. their configs are one click away
save it and steal one tonight
Edgar Gonzalez-Kozlova retweeted
1. Have pedestrian idea.
2. Don’t publish a paper in several years.
3. Submit an R01 on a fantasy.
4. Get R01.
Our review system needs an overhaul.
Edgar Gonzalez-Kozlova retweeted
OUT NOW! NEW RESEARCH from @icahnmountsinai’s @DierdorffLauren, @DeRubeisLab, et al. reveals motor deficits in #DDX3XSyndrome depend on specific brain circuit linking cortex to the brainstem & early intervention can improve motor trajectories! @PNASNews 👉 pnas.org/doi/10.1073/pnas.25…
Edgar Gonzalez-Kozlova retweeted
Seeing a potential benefit of high blood sugar is unusual, to say the least.
High blood glucose improved T cell (CD8+) function to take on cancer, in experimental models and in vitro with human cells, with a mechanistic explanation
academic.oup.com/jimmunol/ar…
Edgar Gonzalez-Kozlova retweeted
I am super excited to see this R01 second percentile score! I know this isn't a notice of award, but to be within weeks of officially starting my lab, this feels huge. Thrilled to see where we can go with this. @StanfordDeptMed @StanfordCVI
weldylab.org
I love papers where researchers do this kind of meticulous but "boring" work that benefits the whole field. About 1 in 3 gene-trait links from transcriptome-wide associations studies (TWAS) give false signs of association. TWAS is a popular method that aims to predict the influence of DNA variants on gene expression activity. The authors cleverly used people who carry broken or duplicated copies of a gene, where the true direction can be inferred.
doi.org/10.1038/s41588-026-0…
Edgar Gonzalez-Kozlova retweeted
See the Full Study in Nature Communications
👉 nature.com/articles/s41467-0…
SECmeres outperform extracellular vesicles as potential blood RNA biomarkers for Alzheimer’s disease
- @EdgarEGK, Swapnil Tichkule, Yohei Nose, John Fullard, @panos_roussos @dogranavneet, et al.
Edgar Gonzalez-Kozlova retweeted
We look forward to hearing from Anirban Maitra, MD, on November 10: Mediators of Restraint in Early Pancreatic Neoplasia.
@Aiims1742 @nyulangone
Hosted by @Poulikos @IcahnMountSinai
Edgar Gonzalez-Kozlova retweeted
🧠 Call for Papers | EVCNA
Explore #EV-Mediated #Communication in the #Gut–#Liver–#Brain Axis with Guest Editor Dr. Vicente Felipo!
Topics include #neuroinflammation, #microbiota-derived #EVs, disease #biomarkers, and #neurological dysfunction.
🔗 oaepublish.com/specials/evcn…
Edgar Gonzalez-Kozlova retweeted
I recently spoke with @PsychTimes about our work on #RNA #biomarkers for Alzheimer’s disease and the potential of #Exosomes #ExtracellularVesicles and Particles in this field.
Link to the Interview:
youtu.be/gmQ4vTHeL1g?si=ia_e…
Psychiatric diseases lack precision diagnostics & blood-based biomarkers. Definitive diagnosis of #Alzheimers remains postmortem. In an interview w/ @PsychTimes, Dr. @dogranavneet shared his research on earlier biomarker testing for #Dementia. Watch Here👉
youtube.com/watch?v=gmQ4vTHe…
Edgar Gonzalez-Kozlova retweeted
Another pan-cancer/tumor agnostic target. Claudin 18.2; 🎯🎯lots of nausea/vomiting though 🤢
Edgar Gonzalez-Kozlova retweeted
Replying to @UGrewalMD
I’m truly sorry you experienced this, and I hope it gets rectified. Perhaps publishers should start paying reviewers. How do they make so much money while academics review manuscripts for free? No wonder some might turn to AI just to get through reviews faster!
Edgar Gonzalez-Kozlova retweeted
🌿 Can plant-derived extracellular vesicles unlock new insights into gut–liver communication?
Our latest Review explores their potential as natural nucleic acid carriers in metabolic liver disease—and the evidence gaps that remain.
📖 Read more: oaepublish.com/articles/evcn…
Edgar Gonzalez-Kozlova retweeted
📢 Meet EVCNA at APSEV 2026 / JSEV 2026!
📍 Tokyo, Japan | 📅 Oct 22–23, 2026 | Booth #22
EVCNA warmly invites you to visit our booth! Meet our editorial team, explore publishing opportunities, and exchange ideas on the latest advances in EV research. See you there! 🤝
Edgar Gonzalez-Kozlova retweeted
BREAKING: Nobel laureate David Baker’s team just published TWO Nature papers in one day!
AI-designed proteases from scratch:
🧬 Cysteine proteases: 19% success rate, functional in mammalian cells.
🧬 Metalloproteases: 36% success rate, with over 10 BILLION-fold catalytic acceleration vs. the uncatalyzed reaction.
From predicting protein structures to designing catalytic function.
📄 Nature papers:
nature.com/articles/s41586-0…
nature.com/articles/s41586-0…
Edgar Gonzalez-Kozlova retweeted
Great to have Tyler Jacks @kochinstitute at @CDI_Einstein @EinsteinMed yesterday! A trailblazing scientist & amazing communicator, now leading the charge on large-scale clinical insight through @break_cancer





































