Head of AI Research & ML Engineering @ 1910
Boston, MA
Joined April 2009
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I've migrated over to Blue Sky where I continue my daily science and engineering posts. See you all there folks! 🦋
bsky.app/profile/rando.insal…
Brandon Moore, PhD retweeted
Today, @1910_ai is thrilled to announce the publication of PEGASUS™, a state-of-the-art AI model for de novo design and optimization of macrocyclic peptides.
▪️Paper: pubs.acs.org/doi/10.1021/acs…
▪️Press Release: businesswire.com/news/home/2…
▪️ BD: To partner on PEGASUS™, [email protected]
Exciting News! @1910_ai PEGASUS™ paper is now published in J Med Chem! This AI model can design macrocyclic peptides that maintain cell permeability, a major challenge for this emerging drug class!
Paper:
pubs.acs.org/doi/10.1021/acs…
Press Release:
businesswire.com/news/home/2…
.
Exciting News! @1910_ai CANDID-CNS™ paper is now published in JCIM! This AI model helps predict which drugs can cross the blood-brain barrier, a major challenge in drug discovery!
Paper:
pubs.acs.org/doi/10.1021/acs…
Press Release:
businesswire.com/news/home/2…
Brandon Moore, PhD retweeted
We are collaborating with @Microsoft to accelerate #drugdiscovery. Using Azure Quantum Elements to supercharge our integrated #AI, computation, and biological automation platform, 1910 can design drug-like molecules better than traditional approaches. msft.it/6012gULlu
#hpc
My tenure at @1910Genetics has allowed me to make significant contributions on our journey to becoming a leading drug discovery company. Now I'm taking our work to the next level as the Head of AI Research and ML Engineering. Lets make undruggable targets a thing of the past!
Three years ago, Brandon Moore became the first employee at @1910Genetics and joined us to realize the vision of making undruggable targets a thing of the past. Today, we announce that he has been promoted to the Head of AI Research and Machine Learning Engineering.
The Office of Science and Technology Policy @WHOSTP45 just released a memo stating taxpayer-supported research must be made available to the American public at no cost. Agencies must implement this policy by 2026!
This is a huge win for open science!
whitehouse.gov/wp-content/up…
Ancient birds gained a taste for sugar via a change in their umami receptors. Eurasian wrynecks (Jynx torquilla) have since reverted back via a small mutation likely resulting in the preference for eating ants over a more omnivorous woodpecker diet.
cell.com/current-biology/ful…
PFAS are a problem because they bio-accumulate and don't naturally break down. The @Dichtel lab just discovered how to degrade these organo-fluorines using simple reagents (lye and DMSO)! This process literally takes the F out of "forever chemicals"!
science.org/doi/10.1126/scie…
Otodus megalodon is one of the largest predators to have ever lived. Recent 3D modeling efforts suggest these massive beasts likely swam faster than any living shark and dined on prey that were the size of killer whales (Orcinus orca)!
science.org/doi/10.1126/scia…
A recent study conducted aboard the International @Space_Station demonstrates how vibrations occurring perpendicular to water droplets in low gravity will cause the liquid to oscillate rhythmically!
journals.aps.org/prl/abstrac…
Paruroctonus soda (Female specimen in photo) and Paruroctonus conclusus are newly identified playa scorpion species discovered by two Bay Area high school students using @inaturalist while adventuring in the Mojave Desert!
zookeys.pensoft.net/article/…
Bonobos (Pan paniscus) pout to gain sympathy during conflict resolution! This adds to the evidence suggesting non-human apes have some level of voluntary control over emotional expression!
royalsocietypublishing.org/d…
Jumping rhythmically on a flat floating surface like a paddle board or canoe can propel it forward via a process called Gunwale bobbing which allows the watercraft to "surf" along its own generated wake!
journals.aps.org/prfluids/ab…
youtube.com/watch?v=RB4zbEHw…
The @DunningHotopp lab recently discovered that fruit fly (Drosophila ananassae) genetic material contains the entire genome of a completely separate bacterial species (Wolbachia)!
sciencedirect.com/science/ar…
Recently discovered imprints of single celled plankton were found embedded in fossilized organic matter. These "ghost fossils" suggest that coccolithophores were more resilient to global warming effects than previously hypothesized!
science.org/doi/10.1126/scie…
The Chinese penduline tit (Remiz consobrinus) carefully buries its eggs within the bottom of its own nests to keep them from tumbling around in strong winds.
sciencedirect.com/science/ar…
Domestic cats (Felis catus) are able to associate names with the faces of their human and feline companions!
nature.com/articles/s41598-0…
