Building the world’s first AI-Driven Digital Organism (AIDO). We're hiring: https://xitter.cf/t.co/JwdGBJvhkL

Palo Alto | Paris | Abu Dhabi
Joined September 2024
The ADIA Lab Symposium opens in Abu Dhabi on Monday, October 26. @dasongle will be delivering a keynote on day two. @adia_lab is an independent research institute working in data and computational sciences, and this is its flagship event. Le's talk is AIDO Cell: A General-Purpose Simulator for Cell Biology.
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Drugs that fail in clinical trials most often fail on efficacy or unexpected toxicity. In @Forbes, our CTO @dasongle traces both to one gap: no tool can yet predict how a molecule behaves inside a living cell. That gap is what AIDO Cell is for. bit.ly/3VjUoGn
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Replying to @dasongle
@dasongle is a featured panelist on the opening panel at Molecules, Models & Agents in San Francisco on Monday, October 5. From Data to Discovery: AI Across Digital Health and Digital Biology, moderated by @dr_alphalyrae of @NVIDIA NVentures, with Michael Aratow of @EllipsisHealth and @kavi_deniz of @tamarindbio. #SFTechWeek
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Out today in @cellpressnews: "A world model of the virtual cell," from our co-founders @ericxing and @dasongle. Their definition of a virtual cell is a stateful, multi-modal, multi-scale simulator, judged on whether it stays coherent across a sequence of interventions. Open access: cell.com/cell/fulltext/S0092…
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A model that makes one prediction and resets only captures a snapshot. AIDO Cell holds the cell's state: perturb it, read it out, then further experiment on the cell you just changed. @DrugDiscovNews on where the virtual cell came from, what's left to prove and how world models are redefining cellular simulation: drugdiscoverynews.com/what-i…
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1/ AIDO Cell is a simulator for cell biology. You instantiate a virtual cell, perturb it, read out experimental measurements, branch it, and perturb it again. An example of how it works, and what it does and doesn't do -> 🧵
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Today we're releasing a preview of AIDO Cell, a world model of the human cell. It simulates one cell across DNA, RNA, protein, through regulatory networks and whole-cell behavior. Not four models handing results to each other. One system.
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GenBio AI researchers' new Perspective paper in @NatureMedicine lays out a blueprint for a simulator of biology: the AI-Driven Digital Organism (AIDO), a system of integrated multiscale foundation models spanning every scale, from molecules to cells to individuals. Not siloed predictors but a connected, hierarchical system: central-dogma sequence FMs, 2D positional encodings, and differentiable computation graphs propagating information bidirectionally across scales. The endpoint is a world model of biology: condition on a state, apply an intervention, roll out counterfactual trajectories. Read the paper: nature.com/articles/s41591-0…
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