krx

New hair loss treatment upgrade: Minoxidil Sulfate in a hydrogel-emulsion. These images are from our Chinese pharmacy partner. They worked on products like L’Oreal’s Stemoxydine at one point. #hairloss #hairgrowth #alopecia #biohacking Preorder link: folligenz.com/products/sulfo… (global shipping)

The return of Jeff Vincent…?😳 stealth mode deactivated.

Either it doesn’t go systemic becuase it isn’t getting into the scalp at all Or it’s going systemic. Either why it defeats their stated goals.

Grey hair is better than bald.

PP405 and stemoxydine might enhance minoxidil’s efficacy by shifting cellular metabolism & inducing pseudohypoxia. Stem cells seem to favor this environment. Add tretinoin on top & you could also promote cell turnover and differentiation, potentially giving you more mature cells with greater enzymatic activity relevant to hair growth. Much of this is still mechanistic, but there’s literature that makes the theory plausible. #hairloss #hairgrowth #longevity #androgeneticalopecia #peptides #looksmaxxing

NYC bodegas now sell GLPs/Peptides 😂 Interesting…all I can say #newyorkcity #peptides #nyc #looksmaxxing #biohacker #weightloss

🚨 SEVERE HAIR LOSS → THIS MUCH CHANGE. These photos are labelled 2 and 14 months on HRT. Their reported treatment history included estradiol, spironolactone, progesterone, oral finasteride followed by dutasteride, oral + topical minoxidil, and microneedling. In androgenetic alopecia, DHT activates androgen receptors in genetically susceptible follicles, gradually driving them to produce smaller, finer hairs. Reducing that androgen signal can help some follicles recover. One approach is to inhibit 5α-reductase, the enzyme that converts testosterone into DHT. Finasteride and dutasteride work here. Reducing testosterone also reduces the raw material available to make DHT. But suppressing testosterone is an UNFAVORABLE trade-off for hair loss alone when those broader hormonal changes aren’t wanted. Another approach is to block the androgen receptor. Investigational GT20029 takes a different approach: getting cells to break down the receptor protein itself. That removes the protein, but doesn’t permanently delete its gene. Estrogens may also help support anagen, the active growth phase, although their direct effects on human scalp follicles are complex. This case cannot tell us how much estrogen contributed. The research opportunity: an estrogen treatment that stays active mainly in the scalp but rapidly becomes inactive once it reaches the bloodstream. If proven safe and effective, that could help a lot of people while limiting hormonal effects elsewhere. Their starting hair loss was severe, so complete restoration wasn’t something to count on. There’s substantial visible improvement, but frontal recession remains. Meaningful partial recovery can still matter, and these photos don’t establish their final regrowth limit. One person, several treatments. Longer hair, styling and lighting also affect coverage, so we can’t isolate what did what. Photo source: r/mtfhairregrowth. #hairgrowth #peptides #minoxidil #mtf #hrt #hairloss #looksmaxxing #alopecia #pharma #science #cosmetics #biohacker #finasteride

Topical minoxidil sulfate has a much longer history than most people realize and at @folligenz we’re up next to continue the development of this hair loss product class. Preorder here: folligenz.com/products/sulfo… As far back as 2007, the German company Sinere was offering Nanominox-MS, a topical minoxidil sulfate formulation, alongside its ethosome-based Nanominox products. Furthermore, minoxidil sulfate has been commonly used in the Brazilian compounding market for nearly 10 years. We can also thank Dr. Ralph Trüeb for helping validate the topical minoxidil sulfate concept in Switzerland. His published clinical research demonstrated promising results with a 5% minoxidil sulfate formulation incorporating Hamamelis.swiss HAIR TONIC (Apomedica Sagl, Switzerland). Now, we’re taking SulfoGenz further. For our new SulfoGenz formulation, we’ve reduced the price per mL while increasing the quantity from 60mL to 90mL. That’s 50% more product per bottle at a lower price per mL. Buy 1 and the next is 50% off in price. So for $130 USD you get around 6 months worth of use. We’ve also partnered with a manufacturing partner in China whose team previously worked on L’Oréal Stemoxydine products. The new formulation will be shipped directly from China. Our goal remains the same: continue improving the formulation while making SulfoGenz more affordable and accessible. More quantity. Better value. A new generation of SulfoGenz. #hairgrowth #peptides #minoxidil #minoxidilsulfate #hairloss #looksmaxxing #alopecia #pharma #science #cosmetics #biohacker