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“Better to be of a humble spirit with the lowly, Than to divide the spoil with the proud.”
Proverbs 16:19 NKJV
MoMD retweeted
33 years ago today Nirvana recorded the best cover in the history of time.
“Where Did You Sleep Last Night”
The song is an American folk song with the most well known version performed by Led Belly.
MoMD retweeted
Here is a rare case: 25 y/o male on the foot @HENRYY_MD @pembeoltulu @Dr_Jukic @CutisViaLux @JMGardnerMD @DrGeeONE @MarcelaSaebL #dermpath ihc is keratin
💯 Great illustration. The contrast between capitalism and socialism couldn’t be clearer. The real-world examples speak for themselves.
Want to know the difference between socialism and capitalism? Part II
Look at Venezuela and Chile.
In 1977, Venezuela was twice as rich as Chile.
It sits on the most oil on Earth.
Chile chose free markets. Venezuela chose socialism.
Today:
- Chile is 4x richer per person.
- Minimum wage: Chile $545 a month. Venezuela 15 cents.
- Inflation: Chile 3.5%. Venezuela 475%.
- Chileans live 8 years longer.
- Freedom score: Chile 95. Venezuela 13.
- Nearly 8 million Venezuelans have fled. Over 700,000 went to Chile.
The country with the most oil on the planet can't keep the lights on.
Same continent.
Same language.
Different system.
Watch the line.
If you're upset that America removed Maduro, ask yourself what side you're really on.
MoMD retweeted
Colonic polyp in middle aged patient.
Can you get the diagnosis at low magnification?
#GIpath #pathology #pathX #pathtwitter
MoMD retweeted
This came to me as negative for malignant cells from the cytotech. These deceptively bland cells are all basically all malignant and BER-EP4 positive. Take a guess about their origin. #boardfodder
MoMD retweeted
How I treat "cancer"
Asymptomatic CLL = observe
Asymptomatic follicular lymphoma = observe
Asymptomatic marginal zone = observe
Asymptomatic mantle cell = observe
Asymptomatic MDS = observe
Asymptomatic hairy cell = observe
Asymptomatic (smoldering) myeloma = observe
MoMD retweeted
Hematologists do not need imaging or clinical history to know the spleen has gone missing.
Howell Jolly Bodies
[don't confuse with Heinz bodies seen in G6PD deficiencies as those always require supravital staining to see, not routine Wright/Giemsa stains]
MoMD retweeted
Plasma cells are amazing! Their appearance reflects an extraordinary commitment to antibody production: the eccentric nucleus, the abundant cytoplasm filled with rough endoplasmic reticulum, the pale Golgi hof. Features we learn early in training become more interesting as we come to understand what they represent.
Some plasma cells persist for decades, producing antibodies against infections we have long forgotten. I find that remarkable. Part of our immunologic history is maintained by these cells, quietly at work in the marrow.
In neoplasia, they may retain that familiar appearance while producing a protein capable of causing profound injury. A seemingly mature plasma cell can belong to a clone whose antibodies damage the kidneys, deposit in tissues, or increase blood viscosity. Its appearance alone tells us surprisingly little about the harm it can cause.
(Images of plasma cell myeloma and rouleaux)
#Hematopathology #Pathology #hemepath #mmsm
MoMD retweeted
It’s official: the @ASH_hematology Image Bank quiz cards will be back @ #AshAPalooza at #ASH2024 🥳
By popular demand, we’re updating the #ASHImageBank flash cards & will give out to at our booth!
Send us Ur favorite images that U think deserve to be included in the deck. U can self nominate.
will include malignant and classical.
MoMD retweeted
Dear hematology lovers & trainees
We are bringing the hematology quiz & flash cards back to ASH-a-palooza #ASH26
We need 2 volunteers to help us at the #ASHImageBank booth on Friday.
Pls let me know if U are interested in joining us. As always, the games will be fun and the competition will be 🔥 🥇
It’s official: the @ASH_hematology Image Bank quiz cards will be back @ #AshAPalooza at #ASH2024 🥳
By popular demand, we’re updating the #ASHImageBank flash cards & will give out to at our booth!
Send us Ur favorite images that U think deserve to be included in the deck. U can self nominate.
will include malignant and classical.
MoMD retweeted
Right on @isliquidbiopsy 🙌🏻
Time for change….
We don’t often think about the utility of liquid biopsy (cfDNA) in myeloid malignancies but it certainly has a role, particularly for capturing the molecular heterogeneity of extramedullary disease.
Read our recent @BCD_AACR paper here for more on this topic.
aacrjournals.org/bloodcancer…
🧬 New in Blood Cancer Discovery: multiomic profiling of myeloid sarcoma reveals distinct extramedullary clonal evolution, transcriptional adaptation, and recurrent RAS pathway activation.
Importantly, ctDNA sequencing captured the molecular composition of myeloid sarcoma, supporting a potential noninvasive approach to profiling extramedullary AML.
@ManelEsteller @ChristianRolfo @UmbertoMalapel1 @ElJanLe @drgandara @MJOSESERRANO19 @ChristianRolfo @RobertoBoreaMD @ErulEnes @ReduzziCarol @ddemiguelperez @PasqualePisapia @BenBleibergMD @Al3ssandroRusso @ESaldanhaMD @eleonora_nicolo @DrMirallas @LuisRaezMD @DrYukselUrun
#LiquidBiopsy #ctDNA #AML #MyeloidSarcoma #ISLB
MoMD retweeted
#Hemepath meets #Breastpath meets #BSTpath
Sclerosing extramedullary hematopoietic tumor (SEMHT) presenting in the breast. SEMHT is a rare manifestation of MPNs. The main dx clue are the atypical megakaryocytes (CD61+).
Read more in IJSP -> tinyurl.com/bdj7nhpv
#PathTwitter
MoMD retweeted
My advice for the newish interns.
Take responsibility.
The right mentality, nothing will happen unless I do it. Check everything with the source, patient and raw data (labs, imaging reports etc).
Do not trust anyone (sometimes even your attending) and independently verify.
MoMD retweeted
CD markers very simplified!
CD34+ = Blast
CD3+ = T-cell
CD19+ = B-cell
CD33+ = Myeloid
CD34+ = Acute leukemia (but which type?)
CD34+ CD19+ = B-ALL
CD34+ CD3+ = T-ALL
CD34+ CD33+ = AML
CD34- CD33+ = APL (promyelocyte differentiated one step above blast)”
MoMD retweeted
Metastatic lobular breast carcinoma (in bone marrow) or chameleon🦎 on a branch? 😬
Pathology 101: NEVER EVER let a BM M bx go without a keratin IHC in a pt with hx of lobular breast carcinoma.
These tumors… keeping me humble & on my toes…😨
#hemepath
MoMD retweeted
Myelodysplastic syndrome with 5q deletion.
Characteristic monolobate megakaryocytes.
#hemepath









































