James A Daniel (@jadaniel81) profile picture

James A Daniel

@jadaniel81

Research neuroscientist. Dopamine release, synaptic biology, molecular neuroscience, drug discovery. Avid cook and heavy metal devotee.

 Göttingen, Germany
mpinat.mpg.de/daniel
Joined July 2014
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  • Following45
  • Followers21
James A Daniel retweeted
Noa_Lipstein (@LipsteinNoa) profile picture
Noa_Lipstein@LipsteinNoa6 Jun 2022
Great initiative to raise money for the study of the rare disorder STXBP1 encephalopathy, by the @FGA_lab. Million Dollar Bike Ride for STXBP1-E patients gofund.me/5f07f7ba
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Researchers led by @ElizarovaSofia, Sebastian Kruss (@KrussLab) & James Daniel (@jadaniel81) succeeded in measuring the release of #dopamine from #nervecells with unprecedented accuracy. 🧠🔬 Find out more in our press release! mpinat.mpg.de/4133470/pr_221…
Dopamin-Nanosensoren messen Signalübertragung zwischen Nervenzellen

Dopamin-Nanosensoren messen Signalübertragung zwischen Nervenzellen

Forschenden am Göttinger MPI-NAT ist es gelungen, die Freisetzung von Dopamin aus Nervenzellen mit bislang unerreichter Genauigkeit zu messen.

mpinat.mpg.de
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1/4 Finally out in @PNASNews! AndromeDA is a nanosensor 'paint' that detects dopamine with high spatial and temporal resolution. Beautiful experiments by @ElizarovaSofia at @mpi_nat. A great collaboration with @KrussLab at @ruhrunibochum and Nils Brose. pnas.org/doi/10.1073/pnas.22…

A fluorescent nanosensor paint detects dopamine release at axonal varicosities with high spatiote...

The neurotransmitter dopamine (DA) controls multiple behaviors and is perturbed in several major brain diseases. DA is released from large populati...

pnas.org
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3/4 AndromeDA detects diffusing dopamine as well as discrete dopamine release events, which appear as 'hotspots'. Hotspot detection was made possible by DART - a machine learning-based algorithm developed by Abed Choaib and Ali Shaib.
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4/4 With AndromeDA we show that discrete dopamine release events are not detected at most axonal varicosoties, and that dopamine release is highly heterogeneous. We also verify that Munc13 proteins are essential in release. Excited to see what more AndromeDA can do in the future!
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James A Daniel retweeted
Sebastian Kruss (@KrussLab) profile picture
Sebastian Kruss@KrussLab26 May 2022
1/3 Finally out in @PNASNews. We developed a paint (AndromeDA) that visualizes dopamine release from neurons. Great collaboration of @ruhrunibochum @SolvationSci with @ElizarovaSofia, @jadaniel81, Nils Brose @mpi_nat tinyurl.com/2ey6nsau
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James A Daniel retweeted
Cordelia Imig (@cordeliaimig) profile picture
Cordelia Imig@cordeliaimig2 Feb 2022
📣We have an open PhD position in our group @uni_copenhagen in beautiful Copenhagen 🇩🇰. If you are interested in synapse biology, #serotonin & the gut-brain axis, then apply before 20 Feb: employment.ku.dk/phd/?show=1… @lundbeckfonden @neuroscience_dk #neuroscience
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Very excited to be a part of the newest MPI!
MPI for Multidisciplinary Sciences (@mpi_nat) profile pictureMPI for Multidisciplinary Sciences@mpi_nat29 Dec 2021
@mpi_bpc becomes @mpi_nat ❗ With the merger of our institute with the #MPIEM, our name will change to Max Planck Institute for Multidisciplinary Sciences. Feel free to tag us with @mpi_nat 🙂.
Image from MPI for Multidisciplinary Sciences (@mpi_nat)
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Excited to be presenting our new work on dopamine imaging at the Synaptic Dimension of Brain Disorders in Baeza. A great collaboration with the @KrussLab!
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