Solvitur ambulando / Studying proteins at Schwede group @biozentrum, Basel (CH) / physics PhD @LIPh_Lab, Padova (IT) / Apprentice Philosopher

Basel, Switzerland
Joined November 2012
Replying to @malikules
👉🏻👈🏻
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Not a neural network, but still with a bunch of layers. Happy New Year! News are coming
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🤔 What did we find? Different patterns produce small discrepancies in model predictions, but healthy and diseased microbiomes still cluster distinctly in the λ and σ space, showing fundamentally different ecological dynamics! 5/n
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How do healthy (blue) and diseased (red) microbiomes look like, when we consider the inferred parameters? There's a lot to say, but stay with me, and consider the following plot [9/n]
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Similarly to the magnetization of the Ising model, we have some order parameters, describing some coarse-grained statistics of the community (e.g. mean abundance) and require to average both over the species and over the disorder. Here's the key intuition of our work... [6/n]
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To link the theory and data, we rely on previous results. Using the magic of replica-trick formalism the theory admits a mean-field Hamiltonian formulation. This formalism allows us to trade complexity (S species) with one species with random potential (here's \zeta!)
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Inspired by Robert May's approach, we draw the interactions from a normal distribution choosing carefully the scaling of the mean and the variance with S. Albeit crude, this assumption leads to a dramatic reduction of the parameters to infer from O(S^2) to just O(1)! [4/n]
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Lotka-Volterra model is a cornerstone of theoretical ecology, describing how the abundances of a local pool of species (S) evolve in time. However, it is typically unfeasible to fit all the O(S^2) parameters, especially with metagenomic data. What's the problem? [2/n]
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Here’s San Marco (Venice) and Sant Antonio (Padova)
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First day of #ISB2023 gone! Glad to meet with such a vibrating community and to learn many new things 🦠🧫🧬👾
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Replying to @DFAUnipd
@DFAUnipd hosted @giorgioparisi for the PhD ad honorem award and the colloquium “on multiple equilibria”, a deep dive into complex systems. Grateful for such an unforgettable day! #phdlife #Physics
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So happy to join as an instructor,with my mentor @SamirSuweis, the << Quantitative Ecological Genomics in the Tara Ocean << school, where we will give two lectures in computational & theoretical ecology! 🌊🐙🌊🦠🌊 en.qlife.psl.eu/actualite/wi…
Ho scritto un articolo sul problema del trolley e memate associate per #rumormagazine #Memes #AI rumormagazineonline.com/lo-s…
youtube.com/watch?v=a1d1S58P… i absolutely need the release of #horsinaround, it would be amazing
youtube.com/watch?v=FYH8DsU2… Anche se è martedì... – at Verona, Veneto