https://nitter.gq/t.co/gfO9jK8jaK(r'pathology|markets|AI',tweets)
Joined February 2011
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Jim retweeted
RAS finally getting drugged is one of the great stories in modern biology, and almost nobody outside oncology understands why it's such a big deal.
YOU'LL LEARN SOMETHING AWESOME TODAY.
i am going to keep this as understandable (and simple) as i can.
OPEN THE THREAD.
🧵
Cheers, chills, and a standing ovation when RASolute 302 showed unprecedented survival on daraxonrasib for patients with progressive pancreatic cancer
Seldom do you sense you’re witnessing a historic moment in cancer care but this feels like ras targeting has arrived
#ASCO26
Jim retweeted
The code is published online, just a tiny bit of Python.
Here’s a breakdown of the regex one-liner:
- lookbehind to skip signal peptides
- scan for rare amino pairs (KK, KR, etc)
- prevent false cleavage match
- enforce minimum spacing + recursive pattern match
Jim retweeted
1/ This internal 2007 Nokia presentation on the first iPhone is a really good example of how incumbents actually get disrupted
Oftentimes, the incumbent already knows what needs to be done. It's just that organizational incentives inhibit the incumbent from doing it
Jim retweeted
If a residency program continues to struggle to match students that rotate, here’s 5 things I think PDs can do to coach their faculty that require little effort but may prevent students from getting “bad vibes” and going elsewhere:
Jim retweeted
when the team’s monomaniacal focus on latency and performance gets applied to … a stove
Jim retweeted
Good morning! I’m so excited to share an update to FREOPP’s analysis of college return on investment (ROI).
We calculate the financial value of 53,000 college degrees & certificates, which can help students and other stakeholders better navigate the college decision.
Jim retweeted
I take slight issue with the exact definition of an anti-bubble here. Strictly from econophysics lit., an anti-bubble is characterized by lengthening cycles past the criticality timepoint (China post-2015 for ex nitter.gq/jimtalksdata/status/74…). 2008 described best as inverse bubble
Jim retweeted
Useful high-level conceptual illustration of AI and human competencies.
Jim retweeted
time to revisit the topic of ANGLISH.
anglish is an umbrella term for a style of english that tries to remove as much foreign influence as possible. prefixes, suffixes, nouns, all of it. it sounds unintuitive, but you pick it up very easily. here's some of my favorite examples:
Jim retweeted
I read about how Dalmatians have a genetic defect of high uric acid which causes blockages. 50 years ago, a guy crossed a pointer with a Dalmatian to eliminate that defect and bred Dalmatians to carry this gene. The breeders went BANANAS about how this was illegitimate
Jim retweeted
It's difficult to compare the ability of a high schooler and a grade-schooler. Fortunately, the NWEA, a massive testing non-profit allows for fair comparisons between students of all ages.
Here are each grade's Math scores:
A thread on student ability and growth 🧵
Jim retweeted
I've obtained one of these "EMP generators" that are intended to cause glitches in gaming machines, either for free gaming or to dump coins.
It's pretty odd.
Jim retweeted
Classes that actively involved students upped test scores in a Harvard class by 33%... but students thought they were learning more from non-active lectures.
The paradox; being challenged results in learning, but it also shows us how little we know, which makes us feel ignorant
# on shortification of "learning"
There are a lot of videos on YouTube/TikTok etc. that give the appearance of education, but if you look closely they are really just entertainment. This is very convenient for everyone involved : the people watching enjoy thinking they are learning (but actually they are just having fun). The people creating this content also enjoy it because fun has a much larger audience, fame and revenue. But as far as learning goes, this is a trap. This content is an epsilon away from watching the Bachelorette. It's like snacking on those "Garden Veggie Straws", which feel like you're eating healthy vegetables until you look at the ingredients.
Learning is not supposed to be fun. It doesn't have to be actively not fun either, but the primary feeling should be that of effort. It should look a lot less like that "10 minute full body" workout from your local digital media creator and a lot more like a serious session at the gym. You want the mental equivalent of sweating. It's not that the quickie doesn't do anything, it's just that it is wildly suboptimal if you actually care to learn.
I find it helpful to explicitly declare your intent up front as a sharp, binary variable in your mind. If you are consuming content: are you trying to be entertained or are you trying to learn? And if you are creating content: are you trying to entertain or are you trying to teach? You'll go down a different path in each case. Attempts to seek the stuff in between actually clamp to zero.
So for those who actually want to learn. Unless you are trying to learn something narrow and specific, close those tabs with quick blog posts. Close those tabs of "Learn XYZ in 10 minutes". Consider the opportunity cost of snacking and seek the meal - the textbooks, docs, papers, manuals, longform. Allocate a 4 hour window. Don't just read, take notes, re-read, re-phrase, process, manipulate, learn.
And for those actually trying to educate, please consider writing/recording longform, designed for someone to get "sweaty", especially in today's era of quantity over quality. Give someone a real workout. This is what I aspire to in my own educational work too. My audience will decrease. The ones that remain might not even like it. But at least we'll learn something.
