We found 14 re-analyses that delivered evidence that we considered both credible and clinically important. Many of these were IPDMA, combining databases. Among these 14, there were 10 simple ‘risk modeling’ studies. Interestingly, >half of these showed variation in both absolute AND relative effects across the different risk strata. There were also 4 ‘effect models’, that more flexibly explored treatment interactions with individual variables for subgroup identification, with credible and clinically important results. These 4 have been validated externally. Most 'effect models', however, yielded 'exploratory' results awaiting confirmation--or more likely refutation. 3/x