@kasterlab

Hunters of microbial dark matter @kitkarlsruhe using meta- and single-cell ‘omics.

 Karlsruhe, Germany
kasterlab.com
Joined July 2019
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  • Followers164
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We are happy to have contributed with a chapter in the book Advances in Applied Microbiology, available at @sciencedirect. It discusses the past and current approaches of single-cell transcriptomics and data analysis in prokaryotes and future challenges. sciencedirect.com/science/ar…
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Our new publication at @MDPIOpenAccess addresses the identification of antibiotic resistance gene hosts in a high-throughput and cultivation-independent approach. Check it out! mdpi.com/2073-4441/15/13/243…

Identification of Antibiotic Resistance Gene Hosts in Treatment Wetlands Using a Single-Cell Based...

Determining the prevalence of antimicrobial resistance (AMR) in non-clinical settings is vital for better management of the global AMR crisis. Untreated and even treated wastewaters are important...

mdpi.com
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Our new publication, released on @IJMS_MDPI, improves Multiple Displacement Amplification for Microbial Single-Cell genomics via volume reduction. It significantly reduces costs while improving genome coverage. You can access it here: mdpi.com/2150834 #mdpiijms

Back to Basics: A Simplified Improvement to Multiple Displacement Amplification for Microbial...

Microbial single-cell genomics (SCG) provides access to the genomes of rare and uncultured microorganisms and is a complementary method to metagenomics. Due to the femtogram-levels of DNA in a single...

mdpi.com
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Out in @FEMSmicro is our new publication, which elucidates the functional roles of prokaryotic proteins using big data and artificial intelligence. Check it out! 💻 🧬 academic.oup.com/femsre/adva…

Elucidating the functional roles of prokaryotic proteins using big data and artificial intelligence

Different principles and methods to functionally characterize and annotate prokaryotic proteins are reviewed, with a special emphasis on machine learning a

academic.oup.com
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Our former PhD student @MorganMicro was awarded the NASA Postdoctoral Proposal Fellowship! We are very proud of her achievements and wish great success in her ascending career! ✨🚀🧪 #WomenInScience
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Check out our new method for combining single cell genomics with metagenomics: Midi-metagenomics. Feel free to add your thoughts and suggestions in the comment section! biorxiv.org/content/10.1101/…

“Midi-metagenomics”: A novel approach for cultivation independent microbial genome reconstruction...

As the majority of environmental microbial organisms still evade cultivation attempts, genomic insights into many taxa are limited to cultivation-independent approaches. However, current methods of...

biorxiv.org
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And in those celebration times e wish all the best for our new PhD, Dr. Morgan Sobol @MorganMicro! 🎉 🥳 🎓 Your teachings and kindness will be missed in our lab.
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Enriching not yet cultured microorganisms from diverse habitats using Silikone foams. Check out the press release and our corresponding paper in the link 🦠🧬🧫
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Big congratulations to the new Dr. Hao-Yu Lo! We wish you the best and brightest future!
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Enriching species of Microbial Dark Matter from water-based environments but also from air? Our solution: Macroporous Silicone Chips: pubs.acs.org/doi/10.1021/acs… with @kasterlab @NiemeyerLab as part of the @The_MicroMatrix project.

Macroporous Silicone Chips for Decoding Microbial Dark Matter in Environmental Microbiomes

Abstract. Natural evolution has produced an almost infinite variety of microorganisms that can colonize almost any conceivable habitat. Since the vast majo

pubs.acs.org
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Hands-on workshop single-cell genomics & bioinformatics - still places available! Application for the workshop @kasterlab @KITKarlsruhe from 21-25.11.22 is open until📅 Nov 1st Registration & info👉 t1p.de/i1id8 Please RT!
Kaster Lab@kasterlab7 Oct 2022
🚨Looking to gain hands-on experience in microbial single cell genomics wet-lab and bioinformatics methods? Then please consider applying to our workshop being held Nov. 21-25, 2022 in Karlsruhe, Germany. Application deadline is Nov. 1! 👉vaam.de/die-vaam/fachgruppen… @VAAM_Microbes
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🚨Looking to gain hands-on experience in microbial single cell genomics wet-lab and bioinformatics methods? Then please consider applying to our workshop being held Nov. 21-25, 2022 in Karlsruhe, Germany. Application deadline is Nov. 1! 👉vaam.de/die-vaam/fachgruppen… @VAAM_Microbes
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Our collab with @NiemeyerLab @RabeKersten is now live on @biorxivpreprint 👇 check it out!
Kersten Rabe@RabeKersten25 Sep 2022
New paper on preprint - now submission. Novel stress senor offering interesting insights into diverse cellular stress reponses 🦠🧪🧐🤓Great work spearheaded by Ahmed Zoheir. If someone is interested in the plasmids, get in contact, we like others to use them.
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‼️ We’re seeking a highly motivated PostDoc for bioinformatic data analyses and pipeline development. Your research will be focused on analyzing metagenomic data from complex microbial communities, as well as single cells. 1/2
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If you love to script, are curious in deciphering complex microbial communities and their individual properties, please submit your application to [email protected]. Also check out our page for more info about our group at kasterlab.com Thx!!
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Our genome assessment pipeline for microbial dark matter, MDMcleaner, is now available via Pip & Conda! Also check out the corresponding publication at NAR: doi.org/10.1093/nar/gkac294

How clear is our current view on microbial dark matter? (Re-)assessing public MAG & SAG datasets...

Abstract. As of today, the majority of environmental microorganisms remain uncultured and is therefore referred to as ‘microbial dark matter’ (MDM). Hence,

academic.oup.com
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Finally got everyone together for a new group photo 🥳
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Kaster Lab retweeted
wilmeslab@wilmeslab25 Apr 2022
Day 3⃣ of #EMBOmicrobial with Anne-Kristin Kaster, John Vollmers, and Florian Lenk from @kasterlab presenting on Single-Cell Omics, thereby further complementing the multi-omics 🧰 to study 🦠 communities
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Looking for a postdoc keen on cultivating and characterizing #Planctomycetes @UniJena @microverse_exc with interest in reactor development and small molecules: microverse-cluster.de/en/job…)
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@The_MicroMatrix tackling cultivation - Interview on Campus Radio KIT with Coordinator @RabeKersten (sorry, only german) 🧪🦠 #microbiology
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