We are working on post-transcriptional regulation and seek to understand the role of RNA elements and cognate RNA-binding proteins for the fate of an mRNA.
Frankfurt am Main, Germany
Joined April 2021
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SchlundtLabNMR retweeted
Spliceosomes use quality control mechanisms to detect and correct mistakes during RNA processing. Our work explores how defective spliceosomes are identified and discarded. #RNA #RNAProcessing #Spliceosomes #QualityControlMechanisms #RMAP
nature.com/articles/s41594-0…
Last action for this year, just in time: Our paper on the evolution of a regulatory RNA element is out! Thank you to the team! Happy 2025 to everyone! 🥂🎊
tandfonline.com/doi/full/10.…
SchlundtLabNMR retweeted
🎉 Herzlichen Glückwunsch! Prof. Volker Haucke @VolkerHaucke erhält den #LeibnizPreis 2025 der @dfg_public für seine bahnbrechende Forschung zu #Lipidsignaling & synaptischer Signalübertragung. 👏 #Wissenschaft #Forschung
Herzlichen Glückwunsch zum #LeibnizPreis! 10 Wissenschaftler*innen gebührt große Ehre. Sie erhalten je 2,5 Mio. Euro für ihre #Forschung. Die Verleihung feiern wir am 19. März in #Berlin – zusammen mit vielen bisherigen Preisträger*innen aus #40JahreGWL. ➡️dfg.de/de/service/presse/pre…
SchlundtLabNMR retweeted
Congratulations to the president of the GBM, Volker Haucke, for winning the Leibniz Preis! 🥂💐
Herzlichen Glückwunsch zum #LeibnizPreis! 10 Wissenschaftler*innen gebührt große Ehre. Sie erhalten je 2,5 Mio. Euro für ihre #Forschung. Die Verleihung feiern wir am 19. März in #Berlin – zusammen mit vielen bisherigen Preisträger*innen aus #40JahreGWL. ➡️dfg.de/de/service/presse/pre…
Thanks to everyone contributing! Well done! 👏👏
Our work on how a conserved core network in the SARS-CoV-2 nucleocapsid NTD affects stability, RNA-binding affinity, and selectivity of the domain is now online @NatureComms.
Thanks to @lab_nmr,
@Schwalbe_BMRZ, @AnnaWacker1303, @Sophie__Korn,
& P13 @desy
nature.com/articles/s41467-0…
SchlundtLabNMR retweeted
Save the date: #GBMLunch on Dec. 11 at 12:30 p.m., organized by Michael Thumm from @uniGoettingen, #GBM Study Group #Autophagy", speaker: @ThomasWollert from @institutpasteur
SchlundtLabNMR retweeted
Registration is open: 76. Mosbacher Kolloquium "AI-driven (r)evolution in structural biology & protein design" from 20.03.2025–22.03.2025
mosbacher-kolloquium.org
Early registration: January 31, 2025
Poster abstracts: January 31, 2025
Please RT!
We are happy to see this one out now! 🙂
Nice collaboration and joint effort! Congrats to the Lassak group and all others involved! Thank you for letting us participate in this nice story! 👇
How to regulate translation of proline containg proteins by the metabolic state of the cell? Finally out in Nat. Commun. Great collaboration with @lab_nmr @pavelkielkowski @qifei9 and Dimitrij Frishmans group: nature.com/articles/s41467-0…
SchlundtLabNMR retweeted
New preprint from @lab_nmr! We exploit a nice set of techniques to decipher the bimodal RNA-binding of Roquin. Thanks @andreas_walbrun and the Rief lab.
biorxiv.org/content/10.1101/…
SchlundtLabNMR retweeted
These recurrent "staple" interactions were reported in our recent @NAR_Open paper. They are inherently non-planar and not decomposable into base pairs, therefore remain invisible to existing annotation tools.
Find out more:
doi.org/10.1093/nar/gkad605
#Research #RNA #Staple #Motif
ALT Examples of staple motifs. (A) UAAN4-staple, motif 44, motif instance 3q1q_3_2120, (B) GA|AG3-staple, motif 43, motif instance 6zu5_11_1125, (C) GN3-staple, motif 33, motif instance 7m4y_33_1582, (D) G3-staple, motif 36, motif instance 7o7y_19_946. The staple strands are shown in pink and salmon. Interacting N and O atoms are shown in blue and red respectively. O2′ atoms are shown in red to designate the minor groove. Potential H-bonds are shown in green.
SchlundtLabNMR retweeted
The epitranscriptome formed by the growing number of modifications occurring within mRNA transcripts.
SchlundtLabNMR retweeted
Two incredible women scientists share a birthday today😊 Marie Curie (1867), two-time Nobel Laureate who coined ‘radioactivity’ & discovered #radium & #polonium, and Lise Meitner (1878), who unlocked the mystery of #nuclearfission, but was (in)famously snubbed for a #Nobel. Both have elements named in their honour: #Meitnerium (element 109) & #Curium (element 96). Happy birthday to these trailblazers!🥳#OTD
ALT Portrait of Maria Skłodowska-Curie ca. 1903, Credit: Public Domain
ALT Lise Meitner around 1900; Picture: Public Domain
SchlundtLabNMR retweeted
Eine Arbeitsgruppe vom Institut für Biochemie @uni_greifswald hat systemisch bakterielle Deacylasen strukturell und funktionell erforscht. Dies gibt wichtige Hinweise für die evolutionäre Entwicklung dieser Enzyme.
nature.com/articles/s41467-0…
Grafik: Michael Lammers
SchlundtLabNMR retweeted
Please retweet 🙏: 2 @ERC_Research-funded Post-doc positions are available in our lab to investigate #RNA structural ensemble and their dynamics in living cells. Application link: rug.nl/about-ug/work-with-us…
More than deserved! Congratulations!
In recognition of his fundamental contributions to the understanding of gene regulation by RNA-binding proteins and the identification of RNA-binding proteins, Prof. Dr. Matthias Hentze will be awarded the Otto Warburg Medal 2025 of the @GBM_eV
SchlundtLabNMR retweeted
Happy halloween to everyone! 🎃👻
Here is a WET spectrum of methanol extract of pumpkin pulp. As you can see - all regions of the spectrum are fairly crowded with signals. To find out what substances are in pumpkins - visit compoundchem.com/2016/10/24/…
#nmrchat #HELLOWEEN
