Assistant professor at Carnegie Mellon University, studies how phase transition organizes biochemistry in normal and cancer cells

Pittsburgh, PA
Joined October 2018
Like every time, I had fun reading this foundational phase separation paper from the Rosen lab
New Online! A demonstration that multivalent interactions drive condensate formation dlvr.it/TTW5Cg
6
21
4,162
Happy to see this coming out at JCB!
Rongwei Zhao et al. @lab_zhang @CarnegieMellon show that, in #cancer cells using the alternative lengthening of telomeres (ALT) pathway, #SUMO levels at #telomeres influence the formation of ALT-associated PML bodies. hubs.la/Q03GK3qh0
2
12
37
6,558
Huaiying Zhang retweeted
📢The third interview in @SDutta_2904’s ‘Asian Microscopists and Cell Biologists’ interview series is with Huaiying Zhang @lab_zhang. We hear about Huaiying’s career path, her research on condensates and her advice for young scientists. focalplane.biologists.com/20…
1
2
11
492
📽️ G&D Tapes 📽️ @rongweiz tells us about their study, recently published in #GenesDev, showing that SUMOylation, DNA repair factors and BLM helicase promote telomeric DNA synthesis and alternative lengthening of telomeres. @lab_zhang Learn more here: ➡️ tinyurl.com/gd351667
5
10
2,411
Carnegie Mellon biologists have discovered the mechanism behind telomere elongation, which has implications for treating cancer. cmu.edu/mcs/news-events/2024… Want to learn more? Register for an upcoming talk by lead researcher Professor Huaying Zhang. cmu.zoom.us/webinar/register…
2
6
581
Thanks for highlighting our work ☺️
In this study, @rongweiz et al. report that SUMOylation, along with DNA repair factors and BLM helicase, promotes telomeric DNA synthesis and alternative lengthening of telomeres. @lab_zhang Learn more here: ➡️ tinyurl.com/gd351667
20
1,105
Check out our new paper. Very proud of you @rongweiz !
I am excited to share my work published on Genes & Development! Our study reveals a novel role of SUMOylation in ALT (Alternative Lengthening of Telomeres) pathway. genesdev.cshlp.org/content/3…
4
2
19
1,546
Happy to share this preprint, in collaboration with @ShilaBanerji and @DMChenowethLab, driven by @DebSBanerjee1 and Tafazwa, where we find high surface tension droplets 💧 can undergo Ostwald ripening in the chromatin while low surface tension droplets cannot.
Interplay of condensate material properties and chromatin heterogeneity governs nuclear condensate ripening biorxiv.org/cgi/content/shor… #biorxiv_biophys
5
2
17
3,132
Thanks for highlighting our work
This Post is from an account that no longer exists. Learn more
1
14
1,577
Huaiying Zhang retweeted
Another great opportunity to learn all things single cell. Plus check out the speaker list, Impressive !!!! #cytometry
5
1
13
3,804
MBoC Call for Papers: Special Issue on #BiomolecularCondensates Submit an article by June 30 to be considered by lead editors: @GladfelterLab, @UNC Jeffrey B. Woodruff, @UTSWNews @lab_zhang, @CarnegieMellon Learn more and submit: molbiolcell.org/biomolecular…
1
1,081
Single Cell Analysis 2024 | ⁦@CSHL⁩ ⁦@cshlcourses⁩ Amazing bootcamp, great speakers, lots of fun. This year Spatial joins the family! Thanks million ⁦@10xGenomics⁩ and ⁦@curiobio⁩ for your generous support this year! meetings.cshl.edu/courses.as…
3
22
1
86
13,395
It’s #cellbio2023 time! Three from the lab are going this year. I will be organizing the MBOC highlights: the future of cell biology session on Saturday and be at the @ASCBiology booth for meeting the MBOC editor on Tuesday;
1
1
11
1,029
Rongwei Zhao will give a talk on SUMO-mediated phase separation on Sunday and Meng Xu will give a poster on RNA-driven phase separation on Tuesday. And I’m the only one without a travel award #proudPI
2
219
Come to lab and see this on the fridge door 😍
1
11
1,054
I’ve been doing teaching prep for the fall semester recently. Last night I had a dream: I said something and the students walked out…
6
586