Postdoctoral Researcher & γδ T cell fan | studying T cell development in the human thymus @taghon_lab @UGent | she/her 👩🔬💻 | https://nitter.gq/t.co/XttsqxZsid
Gent, Belgium
Joined September 2020
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Our human thymus spatial atlas is finally published in @Nature! 🥳
Using a novel common coordinate framework we explored thymic tissue organisation, cell migration trajectories and molecular composition throughout development.
nature.com/articles/s41586-0… @humancellatlas
🚨Out now in @Nature: Our spatial atlas of the developing thymus nature.com/articles/s41586-0…
Together with @Teichlab @MarioniLab and Germain lab we present insights into the establishment of the thymic organ structure in pre- and postnatal life through a new spatial mapping approach.
Lena Boehme retweeted
🚨 Job alert!
The @taghon_lab (@ugent 🇧🇪) is looking for a Postdoctoral Researcher in molecular & computational immunology.
Join us to explore immune cell development in the human thymus using single-cell & spatial omics.
🔗 More info here: tinyurl.com/joinTTlab
#ScienceCareers
I'm beyond excited and super grateful to @FWOVlaanderen for supporting me for another 3 years with a senior postdoc fellowship! 🥳
Stay tuned for cool science on lineage decisions in human T cell development and the role of the thymic microenvironment. 👩🔬💻
@ugent @taghon_lab
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✨ New year, new opportunities:
Come join our team for some exciting projects on human γδ T cell development using single cell and spatial multiomics!🧑🔬💻 We're looking for PhD students and postdocs with interest/experience in computational biology. Reach out for more info!
📢 We're hiring!
Are you:
- Looking for a PhD or postdoc position?
- Interested in human γδ T cells?
- Curious about employing single cell and spatial technologies to study their development?
Then apply now to join our lab @ugent!
ugent.be/en/work/scientific/…
ugent.be/en/work/scientific/…
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If you like scRNA-seq, you'll love CITE-seq. 😍Exploring thymocyte development through this multimodal data set has been utterly fascinating and the level of detail captured by RNA & protein is a real game changer. Get a glimpse of it with our shiny app✨
ccgg.ugent.be/shiny/htsa_thy…
To make our fantastic CITE-seq data set of postnatal thymocytes accessible to the community, we have launched a shiny web app for interactive exploration. Go check it out! ccgg.ugent.be/shiny/htsa_thy…
Moreover, scRNA-seq and Visium spatial data can be found at cellxgene.cziscience.com/col…
Big shout out to the amazing team behind this collaborative effort! @YayonNadav @kedlian @AndreaJRadtke @teichlab @taghon_lab
Super grateful to have had such creative, talented and generous companions on this insightful journey.
Lena Boehme retweeted
Congratulations to this year’s CBTH Scholars! Throughout the program, scholars explored a range of topics and were guided by mentors to elevate their projects to new heights. In addition to advancing their own research, they delved deeper into these key areas:
👉 Bayesian Statistics
️👉 Science Communication
👉 Multi-Layered Data Integration
👉 Data Visualization
👉 Proteomics
👉 Epigenetics
Would you like to join our next cohort? This free program will open for applications in June 2025! Don’t miss out on this amazing opportunity to elevate your skills in Computational Biology.
Porto with the best colleagues 🤗 Truly fascinating talks and posters at #ThymE24 and amazing to see all the different takes on our favourite organ.
@Malyamooo @VhJolien
Big thank you to @EBItraining @EHA_Hematology for selecting me for this year's #CBTH cohort! Had a great time at the first workshop - many inspiring conversations and lots of ideas to take on board for the upcoming months of data analysis. 🧑💻
A big thank you to everyone involved in this week's joint @EBItraining and @EHA_Hematology computational biology training in hematology (CBTH) course.
2025 applications are now open if you want to be in the next cohort of early-career researchers: ehaweb.org/research/research…
ALT EMBL-EBI course. EMBL-EBI and EHA logos. A group of people stand smiling and waving their arms and legs whilst outside on stone steps at EMBL-EBI. Underneath them is a digital banner saying EMBL-EBI and EHA computational biology training in hematology. 17 – 20 April 2024, EMBL's European Bioinformatics Institute. Hinxton, United Kingdom.
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Took us long enough but after 2+ years the thymus team finally managed to meet in 3D. 🎉 Thanks for having me @YayonNadav @kedlian! – at Hinxton, England
Lena Boehme retweeted
The full program of the next European thymus meeting, "ThymE 2024", is now online 👇
thyme2024.pt/?page_id=813
The next European Thymus meeting ‘ThymE’ will be held from May 27 to 31, 2024 in Porto. Very glad to be part of the scientific organizing committee with my friend Nuno Alves.
Join us for this exciting meeting !
#Tcells #Thymus #ThymE #Immunology
4 days of #EMBOMultiOmics have been incredibly inspiring, enlightening and fun (!). Returning home with so many new ideas - can't wait to dive back into my data. Thanks to all the fantastic trainers and other participants for the discussions and suggestions 🤗 @EMBLEvents
Wonderful summary! 👏
Really pleased to share our @preprintclub #highlight on the #preprint of the @teichlab and @YayonNadav @kedlian @lenamboehme, which used a clever approach to yield a detailed #spatial molecular and cellular map of #human #thymic development. Inspiring work, opening new questions.
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Lena Boehme retweeted
For all things #thymus, next up in the Global Thymus Network meetings is Porto in May '24. Organized by (the twitterless) Nuno Alves, with @KruegerLab @TheAbramsonLab @taghon_t @IrlaLab @Vera22380790 thyme2024.pt/
Lena Boehme retweeted
Congrats to our PhD student Michaela for winning the @BDBiosciences @SING_Gent abstract competition! We're super excited to use the #BDRhapsody system to study the role of GATA3 mutations in the development of T-ALL. #singlecell #ugent
Our atlas harbours a vast collection of thymus data sets: scRNA-seq, spatial transcriptomics, multiplex protein imaging and - my personal favourite - 143-plex CITE-seq data, which which allowed us to annotate paediatric thymocytes at unprecedented resolution. 🤩
@taghon_t @ugent
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Check out our thread to learn more about the cellular & molecular organisation of the fetal & postnatal thymus, stromal cell niches and much more. Particularly excited about our space-time analysis of T cell maturation and our finding that CD8 T cells 'like to take things slow'.
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📢Our new preprint is out: We built a spatial atlas of the developing human thymus based on a continuous organ axis.
Fantastic collaboration with the labs of Sarah Teichmann @sangerinstitute & Ron Germain @NIH & proud of @YayonNadav @kedlian @AndreaJRadtke for making this happen.
Happy to share our work, a comprehensive single cell & spatial atlas of the human thymus, which uses our newly established common coordinate framework for the thymus, the Cortico-Medullary Axis (CMA), to spatially explore thymic development.#ThymusCCF tiny.cc/p7udvz
Lena Boehme retweeted
A spatial human thymus cell atlas mapped to a continuous tissue axis biorxiv.org/cgi/content/shor… #biorxiv_immuno