Assistant Professor @BMEIIsinai | Icahn School of Medicine at Mount Sinai 🏥 | Molecular Imaging & Cardiovascular Disease 🔬
New York, NY
Joined June 2019
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Mandy van Leent retweeted
Influenza hijacks myeloid cells to inflict type-I interferon-fueled damage in the heart: Immunity cell.com/immunity/fulltext/S…
Bram and I have been thinking a lot about how PET imaging might shed light on trained immunity mechanisms in CVD🫀. We summarized our ideas in a brief review, now published in ATVB. Curious what you think! ✨
ahajournals.org/doi/10.1161/…
@BMEIIsinai @SinaiHeartBlood
What's better than winning an award yourself? Seeing our student shine! Congrats to Kymani Lewis for taking home 1st prize 🏆 at the BMEII Volunteer Research Day! I'm very proud 😊 @BMEIIsinai @zahifayad
Mandy van Leent retweeted
💥 A gut microbe metabolite that drives #atherosclerosis?
Yes—Imidazole propionate (ImP) triggers vascular inflammation without changing cholesterol.
🧪 We show the pathway—and how to block it.
nature.com/articles/s41586-0… #OpenAccess at
@Nature
@CNIC_CARDIO
#microbiome #CVD
Here's a happy summer picture of our team for you! Taken after a hard day's work 🔬 and well deserved ice cream 🍦
Mandy van Leent retweeted
We are delighted to share our latest findings today in @Nature. We describe cardiogenic regulation of sleep after cardiac injury.
“Myocardial infarction augments sleep to limit cardiac inflammation and damage”
nature.com/articles/s41586-0…
Mandy van Leent retweeted
🔥 New study on #polymersomes for #immunotherapy just out in @NatureNano! Great effort by @WillemNANO at @radboudumc, @AbdelmohsenLab & @vanhest_lab at @TUeindhoven, @mandyvanleent & Bram Teunissen @BMEIIsinai and @AviSchroeder at @TechnionLive!
nature.com/articles/s41565-0…
Mandy van Leent retweeted
In this paper on stress & CVD, we find a novel association between disruptions in the uncinate fasciculus and carotid atherosclerotic burden.
Grateful to @ATawakolMD @zahifayad for this opportunity and to @daveoctweets @mandyvanleent for all the help!
academic.oup.com/eurheartj/a…
Yay! Excited to see this study - led by Carlos Pérez-Medina and Bram Teunissen - out in the world! @BMEIIsinai @SinaiHeartBlood
📢New paper published in #npjImaging @Nature_NPJ 'Macrophage PET imaging in mouse models of cardiovascular disease and cancer with an apolipoprotein-inspired radiotracer' from @mandyvanleent and colleagues @IcahnMountSinai @CNIC_CARDIO
Open access and free to read below👇
Read our new review paper in @NatRevCardiol on PET imaging 🔍of cardiovascular disease!
We talk about fascinating technological developments and discuss recent results from clinical trials 🏨
Now online! BMEII investigators review the latest developments in the world of atherosclerosis PET imaging in Nature Reviews Cardiology. Click here for full access to the article: rdcu.be/dDF85 @mandyvanleent @zahifayad @alexm_official
Mandy van Leent retweeted
💥your new favorite imaging review🔭: “Uncovering Atherosclerotic Cardiovascular Disease by PET imaging“ @NatRevCardiol 💜
rdcu.be/dDF85
👨🏻🔬👩🏼🔬@mandyvanleent @LutgensEsther @zahifayad 🏥@BMEIIsinai @UHZ_UNIFreiburg
Great presentations by Trea, Anna and Sheqouia in the poster session at #BMEII2024! – at New York, USA
Mandy van Leent retweeted
Interested in studying how the brain controls our cardiovascular health? Come and join our growing lab at MGH and HMS as a PostDoc. Expect full support, scientific freedom, and a very friendly environment. Check here for details xitter.cf/jobRxiv/status/1770102… Please RT!
Postdoctoral Fellow in Experimental Neurocardiology at MGH/HMS @mghcvrc
Interested in studying how the brain controls our cardiovascular health? Come and join our growing lab at MGH and HMS as a PostDoc.
jobrxiv.org/job/massachusett…
#cardiovascular_diseas...
jobrxiv.org/job/massachusett…
Thanks Roy! Good to see you!
Outstanding talk by @BMEIIsinai @mandyvanleent on imaging host response in inflammation at @ESMI_society #EMIM2024
Mandy van Leent retweeted
Happy holidays from @BMEIIsinai Here to a great end to 2023 and we welcome 2024 with feelings of gratitude, optimism and strength #notafraid
I've been waiting to see these CCR2 PET images of patients with myocardial infarction. Looks really promising! 👏
RESEARCH| Lavine et al. establish the feasibility of C-C chemokine receptor 2 (#CCR2) #imaging, a marker of inflammatory monocytes/macrophages, in patients that suffered a #MyocardialInfarction| @LavineLab, Yongjian Liu, @WUSTL nature.com/articles/s44161-0…
👉rdcu.be/dmYvv
Mandy van Leent retweeted
We could not be more excited to kick off the next five years of studying the connections between stress & cardiovascular health with the best team! @nih_nhlbi
mountsinai.org/about/newsroo…
Mandy van Leent retweeted
Last week, the CVRI joined colleagues for the 2nd annual NYC Inter-institutional Cardiovascular Retreat - thank you to all who came and presented their work!
Mandy van Leent retweeted
In mouse models of #cvMI, multiparametric immunoimaging w/ preclinical MRI & PET imaging methods characterize the differential immune responses in the heart, bone marrow & spleen. Read the new #JACCBTS study by @mandyvanleent, et al here: bit.ly/3smhUDR #CardioTwitter
