MD/PhD @StonyBrookU | PhD in mycobacterial genetics in the @jcslab | incoming FM PGY-1 @ruralresidency
Stony Brook, NY
Joined April 2010
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At last, in print sans "pre-"! Grazie mille to my co-authors/co-conspirators @jcslab at beyond, w/o whom I'd still be stuck on a translation problem! TL;DR: Mtb codon context bias may be baked in to regulate transcription, but I hope you'll give it a read. journals.asm.org/doi/10.1128…
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FINALLY! Thanks to the indomitable @JaisinghaniN87 we proudly present the ultimate Mtb cell wall proteome and some surprising-- and exciting-- members: Type VII secretion substrates EsxB & EsxG! 1/n biorxiv.org/cgi/content/shor…
Infinite thanks to @jcslab and the many brilliant/generous collaborators who made this science adventure possible! ✨💕🥲 And thanks, of course, to mycobacteria for being such interesting weirdos.
Hurrah! Announcing the awesome thesis work of @noosly!
Or, how synonymously recoding genes in mycobacteria is like Bjork’s “It’s Oh So Quiet”. 1/n biorxiv.org/content/10.1101/…
Nuri retweeted
Hurrah! Announcing the awesome thesis work of @noosly!
Or, how synonymously recoding genes in mycobacteria is like Bjork’s “It’s Oh So Quiet”. 1/n biorxiv.org/content/10.1101/…
Nuri retweeted
New preprint — and a new (to our knowledge) mechanism by which synonymous codons can regulate gene expression!
Looking forward to feedback.
Synonymous codon substitutions regulate transcription and translation of an upstream gene biorxiv.org/cgi/content/shor… #bioRxiv
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This is conceptually insane. nature.com/articles/s41467-0…
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Check out our, @GeneWeiLiLab @julianstanley_, new paper showing that a large fraction of RNA molecules in bacteria are fragments of canonical full-length mRNAs with consequences for differential RNA-seq analysis: doi.org/10.1093/nar/gkac295
Nuri retweeted
Synonymous sequence changes are not necessarily silent, and here they can have life-or-death consequences.
Now out in @eLife by former lab members @JIPerlmutter and Jane Meyers. Thanks to editors and reviewers for the constructive and kind review.
elifesciences.org/articles/6…
Nuri retweeted
Happy to have penned this review on bacterial lipidomics with @JaisinghaniN87! All reviews co-edited with @basktastic for this #lipidtime issue coming soon....
Free access to our paper: sciencedirect.com/science/ar…
Nuri retweeted
🚨I wrote a big piece about how Delta affects the pandemic endgame.
Many folks are upset & confused by the last month. Here's an attempt to reset expectations, lay out our goals, map the near-term future, & show how the pandemic ends--which it will. 1/
theatlantic.com/health/archi…
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JSeeliger Lab is hiring a postdoc! See official ad below and please help spread the word.
Wanted: #microbiology /#biochemistry/chem bio experience and eagerness to explore all things mycobacteria w/ a focus on the cell envelope.
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Excited for @BBM today and tomorrow! For fun in mycobacteria visit @jcslab 5-min poster talks:
#47 @noolsy - unexpected consequences of gene recoding on expression
#58 @LiaParkin - exploring lipid transport functions of a membrane transporter and lipoprotein
Welcome to our annual meeting #BBM2021! You can watch a stream live here: youtube.com/watch?v=faAVHOLB…
Nuri retweeted
Excited to share our first preprint on inhibitors of M. tuberculosis that we characterized using a competitive activity-based protein profiling platform. A long-haul team effort from @jcslab @AldridgeLab @canaanlab and the Cravatt lab. 1/n
