Career Development Fellow and Group Leader at @UniofOxford. Interested in everything to do with vaccine immunology. Views are my own. He/his.
Oxford, UK
Joined February 2010
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I've decided to move to Bluesky. Please come find me @nprovine.bsky.social if you'd like to keep seeing updates on our research. As an enticement, we have two newly published studies highlighted over there. I hope you enjoy them!
(This account will be left open as a record)
Nick Provine retweeted
Human tonsil organoids reveal innate pathways modulating humoral and cellular responses to ChAdOx1 biorxiv.org/cgi/content/shor… #biorxiv_immuno
Nick Provine retweeted
I am really excited to announce that our paper (@PKlenermanLab) exploring MAIT cell transcriptional and TCR repertoire diversity in human blood and liver has been released @NatImmunol nature.com/articles/s41590-0… #MAITcells
Nick Provine retweeted
Hi! I am again posting videos from the lectures in my #Immunology course on YouTube this semester. Here is the link to the Fall 2022 playlist:
youtube.com/playlist?list=PL…
Videos from Lectures 1 and 7 need editing and will be available eventually, today's lecture (11) is on the way!
Nick Provine retweeted
Some of the work from my PhD is now published in @JCI_insight 🎉👩🏼🔬 – at Philadelphia, PA
CMV-associated T cell and NK cell terminal differentiation does not affect immunogenicity of ChAdOx1 vaccination: buff.ly/3wOxKrc
@HannahRSharpe14 @PennMedicine
#COVID_19 #Vaccines
Nick Provine retweeted
⭐️ Computational Cellular Genomics PostDoc Wanted
• Investigate inflammatory disease + cancer
• Integrated with wet lab validation
• Fixed term, full time for 3 yrs
💭 Think this could be you? Apply by 12pm 20.04.22
my.corehr.com/pls/uoxrecruit…
Amazing talks today by Alexandra, Michael, and Tanita! Huge privilege to be amongst such good company of up-and-coming scientists!
Ready for #EMBlInfectionBiology Session 3 ‘Host genetics and immunology’? 🔬🧫 We will hear from:
🔹Aleksandra Kolodziejczyk @Elinav_Lab
🔹Michael Connor @midweekwarrior @institutpasteur
🔹Tanita Wein @TanaWein @WeizmannScience
🔹Nicholas Provine @nprovine @UniofOxford
Nick Provine retweeted
A blood atlas of COVID-19 defines hallmarks of disease severity and specificity: Cell disq.us/t/44jm0hc
Excited to share our latest work (with co-first author @aliamini419 ) examining how adenovirus vectors activate Vd2+ gdT cells: doi.org/10.1002/eji.20214936…
Fully formatted version just published at @EurJImmunol
This contributes to a growing literature that Vd2+ gdT cells can be potently activated by cytokines.
Our work: doi.org/10.3389/fimmu.2018.0…;
@scientist_JJ @KentLaboratory nice paper: doi.org/10.1016/j.celrep.202…;
@soumya_boston
and Brennan groups' nice study: nature.com/articles/s41467-0…
As always, a great team effort from @PKlenermanLab. Special acknowledgements to co-authors and collaborators: @TheLucyGarner @DoctorFitz @SenDeviMithu @ReitheraSrl @EleanorBarnesOx @ajpollard1, and everyone else not on Twitter.
Nick Provine retweeted
Congrats @aliamini419 @PKlenermanLab 🎉 great job!
Drumroll please 🥁 we have the winners of the #BSI21 poster prizes!
🏅 P008 @ToshiM32, P091 @eberlmat, P133 Gareth Purvis, P197 @FentonThomas, P251 @DavidLeckyBio, P274 Ali Amini @aliamini419, P282 Ashna Patel, P383 Lucy Curham 🏅
Congratulations to all the winners!
Nick Provine retweeted
Come and see my talk on MAIT cells (the best T cell subset!) this afternoon @bsicongress - T cells and infection (part 2) #BSI21 @PKlenermanLab
I highly recommend this position to anyone looking for a post-doc. I had the great pleasure to work with Pablo for 5 years. An excellent scientist and colleague. His lab is doing really exciting work!
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Excited to share our latest research in @PLOSPathogens examining immune parameters associated with worse outcomes in severe COVID-19 and influenza virus infection. Activation of #MAIT cells was the strongest predictor of poor outcome in both diseases.
journals.plos.org/plospathog…
Huge pleasure to work with @BicanicTihana and her group at @SGUL_III. Particular pleasure to work with my fellow lead authors @JonathanYoungs and Nicholas Lim.
Special thank you to @aliamini419 and @HannahRSharpe14 for working with me on the flow cytometry portion of the paper.
These findings contextualize studies from @SandbergLabKI and Agnes Lehuen, which linked MAIT cell activation and worse outcomes in COVID-19. From our broad screen of immune responses, MAIT cells were in fact the strongest predictor.
science.org/doi/10.1126/scii…
nature.com/articles/s41590-0…
Nick Provine retweeted
Want to know what it takes to build long-lasting, protective CD8 T cell memory after #vaccination?
Check out my latest at @NatImmunol with Paul Klenerman @NDMOxford, @ImmunobiologySG , @LabOxenius, @PhilippeKrebs1, @SandraRing7.
nature.com/articles/s41590-0…
Nick Provine retweeted
Ecstatic that the main findings from my postdoc on the pathogenesis of Checkpoint Inhibitor colitis are out in @AmerGastroAssn @AGA_Gastro Wonderful to work with so many amazing clinicians and scientists @NDMOxford @MRC_WIMM @OUHospitals @LivUni et al.
gastrojournal.org/article/S0…