
Co-Founder @FacetWealth, Partner, HighRidge Ventures
Austin, Texas
Joined March 2009
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Patrick McKenna retweeted
I’ve always found people who bristle at “American exceptionalism” kind of… weird. Not because I lack self-awareness — I’ve spent my career cataloging every way this country fails to live up to its own rules. But that’s exactly why I love it so damn much. We built a system designed to be shamed by its own founding documents, and it still delivered one of the most spectacular, world-altering runs in human history. A genuine force for human flourishing.
I also found the argument against American exceptionalism to be historically illiterate. Here’s a sample of what we were first at:
• The first large-scale democratic republic in human history — not a city-state, not a monarchy with a parliament bolted on, but a bold continental experiment in self-rule, popular sovereignty, and ordered liberty.
• A written Constitution (1789) with separation of powers and checks & balances — still the oldest national constitution in force anywhere.
• The Bill of Rights (1791): the first time a nation wrote “the government cannot touch these” into supreme law and actually meant it. A dare the world copied — from later rights charters to the Universal Declaration of Human Rights.
• Public land-grant universities and mass higher education (Morrill Act), opening college to ordinary people no aristocracy would have let near the gates. (but don’t get me started about what happened after we started. Massively federally funding it.)
• Kitty Hawk, 1903 — first controlled powered flight.
• The Moon, 1969 — still the only ones who’ve been there.
• The world’s largest economy since ~1890, powering unprecedented prosperity through grit and genius.
• The assembly line, skyscraper, transistor, personal computer, ARPANET — the backbone of the modern world.
• Telephone, phonograph, GPS — connecting and powering daily life.
• Surgical anesthesia, polio vaccine — saving and transforming millions of lives.
• Jazz, blues, rock ‘n’ roll — brand new American art forms that conquered the globe.
• Hollywood’s dreams, blue jeans, bourbon, and a culture so open a kid like me could devour sushi, burritos, stuffed cabbage, and tabouli in the same week and rightfully think of it all as American.
That’s the part that fills me with genuine love and pride: not just the power or the wins, but the appetite for freedom, creativity, and reinvention. The audacity to say “We the People” and keep trying to live up to it.
What do you love most about this truly exceptional country? 🇺🇸
Patrick McKenna retweeted
They capture the exact moment when a developing heart shifts from silence to its first beat. There is no “switch”: many cells gradually become active and, upon crossing a critical threshold, the entire tissue suddenly synchronizes.
Add to your consciousness follows and reading list
The science of consciousness needs advanced meditation.
Despite decades of research and incredible advances in neuroscience and AI, we are still no closer to explaining how or why consciousness arises in the brain. The hard problem remains as hard as ever.
At the Meditation Research Program at @harvardmed & Mass General (MGH), we argue that a key reason for this impasse is the field’s near-exclusive focus on ordinary states of waking consciousness. These states may actually obscure the mechanisms we seek to understand.
In our new paper, Toward a Neuroscience of Consciousness Using Advanced Meditation, just out in Neuroscience & Biobehavioral Reviews, Jonathan M. Lieberman and I take this argument one step further. We propose that advanced meditation—states and stages of practice that unfold with increasing expertise—offers a powerful and largely unexplored opportunity for a rigorously theory-driven neuroscience of consciousness.
Notably, over the past several years, our team has combined cutting-edge neuroimaging with sophisticated analytic tools to study two highly advanced yet replicable meditative phenomena: advanced concentrative absorption (sometimes called jhāna) and meditative endpoints such as cessation events (related to what is known as nirodha).
These are phenomenologically stripped-down states in which consciousness is either radically altered or temporarily suspended altogether. Precisely for this reason, we argue they are exceptionally well suited for what is often called a minimal model approach to consciousness research.
If these states approximate the simplest forms of conscious experience that a human being can have, then studying them neuroscientifically may allow us to identify candidate necessary and sufficient neural conditions for consciousness at all.
This approach will not solve the hard problem overnight. But it may help resolve many of the “easier” problems (which remain profoundly difficult!) and provide a powerful test case for evaluating competing theories of consciousness based on their ability to explain minimal states.
Compared to other non-ordinary states now receiving scientific attention, such as psychedelic states, advanced meditation offers several unique methodological advantages. More than that, we argue it offers a uniquely powerful and underutilized tool for answering one of science’s most fundamental questions: what does it take for us to be conscious at all?
If you agree or disagree that consciousness research should look beyond ordinary states, we welcome discussion, critique, and sharing of this work among researchers and others interested in advancing a more explanatory science of consciousness🙏
AI will expand human creativity. Technology alway has. Let’s keep our heads out of the sand and stone wsj.com/opinion/ai-is-a-gift…
Patrick McKenna retweeted
My new op-ed in @dcexaminer. There's a lot we can do to prevent crime. But when crime does occur, consequences should follow swiftly & with certainty.
That's not what happens today.
We need to solve more crimes, more quickly. How? More detectives, better training, smarter use of technology.
It's time to invest in investigations!
Most Americans assume that if you commit a serious crime, you’ll likely face consequences. The reality is starkly different. Even for the most serious crime — murder — the national clearance rate hovers around 55%. | RESTORING AMERICA trib.al/QLQduhH
Patrick McKenna retweeted
Happiness is presence.
A very small percentage of our brain is focused on the present.
Most of the time, its worry about the future or regretting the past.
This is what makes being grateful so hard.
$60M of impact! Congratulations @oneamericaworks team and supporters
Tech Talent Is Not Just In Silicon Valley, It’s In The Trust Network via @forbes forbes.com/sites/stand-toget…
Patrick McKenna retweeted
"The past is entirely contained in your head. It is nowhere else. The present is all that exists and that is where YOU exist."
@naval
Patrick McKenna retweeted
Generative AI has been around longer than you might think. #IKYMI #TheMidPoint #FounderStories #Pittsburgh @dasphd
The Mid-Point: Dietrich Stephan - Cyto Ventures
Dietrich launched CytoVentures to give biotech founders access to infrastructure, expertise and a network of equity investment. Cyto has helped raise over $400 million for about a dozen startups.
Patrick McKenna retweeted
In this episode of #TheMidPoint, @JasterAthletes founder, @jordonr, sits down with @patrick_mckenna to discuss his perspective on building a service based business despite not being a traditional techie.
buff.ly/3r3kf6m
#founderstories #Pittsburgh #podcast




















