@petertdoohan

PhD student @OxNeuro // Interested in how goals structure our behaviour

 Oxford, UK
Joined September 2022
  • Tweets41
  • Following275
  • Followers148
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Peter Doohan retweeted
Tim Behrens@behrenstimbOct 26
New review about computations in PFC, led by two deep thinkers, @GabyMohamady and @kristorpjensen with contributions from many more. Discussing the implications of a bunch of exciting recent PFC findings for how we think about PFC computations.
Mohamady El-Gaby@GabyMohamadyOct 26
World models are central to intelligence - but how do we actually use them to behave flexibly? We review emerging findings on how the PFC’s inner dynamics translate structured knowledge into action. osf.io/preprints/psyarxiv/j7… 🧵 1/15
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World models are central to intelligence - but how do we actually use them to behave flexibly? We review emerging findings on how the PFC’s inner dynamics translate structured knowledge into action. osf.io/preprints/psyarxiv/j7… 🧵 1/15
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Peter Doohan retweeted
Tim Behrens@behrenstimbOct 22
Super proud of many things about this work from the amazing @KrisTorpJensen. The work is one of my favourite things ever from the lab. Also super proud of Kris for choosing to send it to @elife -we get to see Kris explain every figure! elifesciences.org/articles/1…

A mechanistic theory of planning in prefrontal cortex

Recently discovered sequence representations in prefrontal cortex can be combined with the ubiquitous principle of neural attractor dynamics to support planning in complex environments.

elifesciences.org
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Thrilled to see our paper in @NatureNeuro! We combine neural networks with symbolic regression to turn how people value information into a simple, interpretable equation. We hope it's a useful recipe for making flexible models interpretable. doi.org/10.1038/s41593-026-0…

Interpretable abstractions of artificial neural networks predict behavior and neural activity...

Nature Neuroscience - D’Ambrogio et al. combine deep learning and symbolic regression to report an interpretable equation of how humans value information. The equation predicts choices and...

nature.com
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Amazing work! Featuring one of the most convincing prefrontal silencing results I’ve ever seen.
Peter Doohan@petertdoohanJun 11
How do brains plan actions towards goals? To get at this question we studied mice navigating complex mazes as goals changed on every trial 🧵 New work with Thomas Akam @behrenstimb @KrisTorpJensen now on BioRxiv: biorxiv.org/content/10.64898…
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Peter Doohan retweeted
Tim Behrens@behrenstimbJun 11
This is one of the coolest things I have been involved with. Truly flexible navigation in mice. Real insight into how mPFC computes the plans. Great fun to see what PFC is doing with those hippocampal theta sweeps. From the awesome @petertdoohan
Peter Doohan@petertdoohanJun 11
How do brains plan actions towards goals? To get at this question we studied mice navigating complex mazes as goals changed on every trial 🧵 New work with Thomas Akam @behrenstimb @KrisTorpJensen now on BioRxiv: biorxiv.org/content/10.64898…
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How do brains plan actions towards goals? To get at this question we studied mice navigating complex mazes as goals changed on every trial 🧵 New work with Thomas Akam @behrenstimb @KrisTorpJensen now on BioRxiv: biorxiv.org/content/10.64898…
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Finally, a big thank you to all our co-authors Yaqing Chen, @BeatrizSimG, @charlesdgburns, Xiao Qin, Josie Emery, Ryan Cini, Mark Walton + everyone in the Akam and Behrens labs across SWC & Oxford for their support!
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All data, analysis code & relevant docs are publicly available. Ready for anyone to start making their own discoveries 💡 See code & data availability section of manuscript :) biorxiv.org/content/10.64898…

Structured and flexible representations in medial-frontal cortex support goal-directed navigation

Humans and animals plan actions to achieve goals in worlds that are complex and continually changing. While planning is critically dependent on the prefrontal cortex in humans, little is known about...

biorxiv.org
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Our paper "Memory reactivation generates new, adaptive behaviours that reach beyond direct experience" is now out nature.com/articles/s41598-0… ! With @AnnieBRawson, Jill O’Reilly and @HelenCBarron at @MRCBNDU @NDCNOxford 1/6
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Peter Doohan retweeted
Cortex Club@CortexClub9 Nov 2024
Our next CorTech talk is scheduled for Monday, November 11th at 4pm with @EnnyvBeest in Biochemistry Seminar Room 1. Title: Tracking Neurons Across Days with High Temporal Resolution. Enny will lead a brief tutorial afterwards so please bring a laptop!
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A hierarchical coordinate system for sequence memory in human entorhinal cortex. biorxiv.org/cgi/content/shor… #biorxiv_neursci
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Peter Doohan retweeted
Josh Selfe@joshsselfe17 Oct 2024
Ever wanted to explore the driving forces underlying inhibitory neuronal signalling? We did! So, for my MSc in @JosephRaimondo lab, we developed the all-optical approach ORCHID - all-Optical Reporting of CHloride Ion Driving force. Now out in @NatureComms nature.com/articles/s41467-0…
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Peter Doohan retweeted
Cortex Club@CortexClub5 Oct 2024
Our second talk of the year is scheduled for Wednesday, 9th October at 4pm with Lisa Spiering in the Pharmacology Lecture Theatre. Title: Controllability and cause in human collaboration. Post-talk, we will head to the Lamb and Flag at 5.15pm for some drinks and chats!
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