@pranasag

biochemist (PhD) behind a computer at KIT | notorious metalhead | prev @VUamsterdam, @UniHeidelberg & @VU_LT | rookie bassist, former saxophonist

 Karlsruhe, Germany
pranasag.github.io
Joined September 2018
  • Tweets175
  • Following455
  • Followers144
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An early Valentine's present for you from the Systems Biology Lab @ALIFE_VU. Sweet dreams... and genome-scale models are made of this. We have collected our best (and worst) practices into a practical guide on the art of genome-scale modeling.
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bioRxiv SysBio@biorxiv_sysbio4 Nov 2024
Mitochondrial efficiency determines Crabtree effect across yeasts biorxiv.org/cgi/content/shor… #biorxiv_sysbio
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Finally putting some of the recent adventures on display. On the 8-11th July, we held the 3rd summer school of Economic Principles in Cell Biology @economic_cell. Together with @daja_sz we gave a lecture on our chapter "An inventory of cell components". – at Paris, France
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It was a cozy, interdisciplinary, and jolly symposium, meeting a lot of fellow colleagues (some of them - after 4 years of Zooming). We hope to revamp the program and also change the venue for the next year - Vienna, we kindly ask to unveil your hospitality in all of its beauty! – at Paris, France
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And a shameless plug - if you are reading this, and feel like you should be a part of this community (especially the informal part of it) please have a look and let us/me know: principlescellphysiology.org…
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Christian Kost@KostChristian8 Jul 2024
Are you interested in mutualisms? Have you always wondered how these cooperative interactions emerge and coevolve? If the answer to these questions is YES, then please consider joining my vibrant group as a PhD student. Please RT. More details👇 shorturl.at/5ZP7R
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FrezzaLab@FrezzaLab25 Apr 2024
Presenting metabolomics analyses: what is in a number? embopress.org/doi/full/10.10… @JohannesMeiser and I wrote this short piece to raise awareness about how present metabolomics data. We hope you will find it useful. Any comment is welcome! thanks @DanielKlimmeck for the support!

Presenting metabolomics analyses: what’s in a number?

The EMBO Journal - Metabolism analysis is complex, accordingly representation and interpretation of metabolomics and fluxomics data is prone to pitfalls, which, if not considered, can lead to...

link.springer.com
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Megan Barkdull@meganbarkdull_14 Feb 2024
Happy Val-ant-ine's Day!
a black and white line drawing of two female worker ants, their gasters overlapping and shaded pink to form a heart shape.

ALT a black and white line drawing of two female worker ants, their gasters overlapping and shaded pink to form a heart shape.

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Today we present the first public version of what we call a 'GEM handbook', and invite you to have a look on the lab's website: teusinkbruggemanlab.nl/our-t… Thanks to all the contributors! Couple of them still have Twitter (@morofrancesco17, @Afrikanerd1993, @JuliusBattjes )
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Please spread the love* (St. Valentine's around, after all), and please get in touch if you are interested in contributing! *CC-BY-NC
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good papers@paperperday5 Jan 2024
A fast method to distinguish between fermentative and respiratory metabolisms in single yeast cells "Respiratory cells, pulsed with a respiration blocker, show reduced ATP levels detected by ATP sensor, while fermentative cells maintain their ATP values." doi.org/10.1016/j.isci.2023.…
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Rodrigo Feitosa@rsmfeitosa24 Dec 2023
– at Curitiba, Brazil
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If you are interested how preculture conditions prepare Lactococcus cremoris for future sugar consumption have a look at a proteome study by S. Douwenga, Berdien van Olst, Michiel Kleerebezem, @BasTeusink ..@JournalSpectrum journals.asm.org/doi/10.1128…

The hierarchy of sugar catabolization in Lactococcus cremoris | Microbiology Spectrum

The availability of nutrients to microorganisms varies considerably between different environments, and changes can occur rapidly. As a general rule, a fast growth rate—typically growth on glucose—is...

journals.asm.org
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New preprint! 📰 Using metabolic pathway analysis, we enumerated metabolite exchanges in microbial metabolic models and found a surprising hierarchy of formal pathway definitions. Amazing job by Ylva Wedmark getting to the bottom of all this 😀 biorxiv.org/content/10.1101/…

A hierarchy of metabolite exchanges in metabolic models of microbial species and communities

Motivation The metabolic network of an organism can be analyzed as a constraint-based model (CBM). CBM analyses can be biased, optimizing an objective such as growth rate, or unbiased, attempting to...

biorxiv.org
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Matti Gralka@MattiGralka3 Aug 2023
Please share! I am looking for a PhD student in Amsterdam, together with @MullaYuval, to study phages in microbial communities. Interested? Check the job ad to apply or contact me with questions! MSc required, deadline Sept 30. workingat.vu.nl/ad/phd-posit…
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Bas Teusink@BasTeusink5 Jul 2023
our @AIMMS1 festival @VUamsterdam was such a great success! Thanks to all our researchers, from PhD to prof, our sponsors and external partners. We will continue to build interdisciplinary connections to accelerate molecular research
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Chentomology@czbugsart27 Jun 2023
Ant character design chart 🐜
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Daran-Lapujade@PascaleDL21 Jun 2023
If you are interested in Synthetic Genomics and Synthetic Cells and have experience in (yeast) molecular biology, you might want to check the post-doctoral position now available at IMB. Check it out at #genomics #syntheticbiolog…lnkd.in/eJ4pDNx4 lnkd.in/eX_WVibP

#genomics #syntheticbiology #synbio #yeast #molecularbiology #postdoc #postdocposition | Pascale...

If you are interested in Synthetic Genomics and Synthetic Cells and have experience in (yeast) molecular biology, you might want to check the post-doctoral position now available at IMB. Check it out...

linkedin.com
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Lukas Gerasimavičius@L_Geras19 Jun 2023
Our @jmarshlab/@MRC_HGU investigation of structural protein stability predictors using deep mutational scanning (DMS) data has been published in Protein Science @ProteinSociety doi.org/10.1002/pro.4688

Correspondence between functional scores from deep mutational scans and predicted effects on...

Many methodologically diverse computational methods have been applied to the growing challenge of predicting and interpreting the effects of protein variants. As many pathogenic mutations have a...

onlinelibrary.wiley.com
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Been pitching a part of the #MetaAnts project on quantitative underpinnings of metabolic division of labor in ant colonies. To be continued, in collab with our #HSFP grant colleagues at @ALIFE_VU @AIMMS1 @adriaexists @social_fluids – at Zurich, Switzerland
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