Strong link between early viral load reduction by anti-COVID treatments and clinical efficacy.
Helps rapidly progress better treatments.
Bravo, great work by Khoury, Davenport and team. @IAP_Sydney @TheDohertyInst @KirbyInstitute @viralvaxlab medrxiv.org/content/10.1101/…
Great work team! Yes, keep getting your vaccines people. Although the difference between WT and variant boosters is pretty subtle in some healthy subjects, the variant booster will help some vulnerable groups stay out of hospital.
Get boosted! Our new research in Nature Medicine shows both normal and bivalent boosters increase antibody levels, though variant boosters give on average 60% more antibodies. #COVID19Abs nature.com/articles/s41591-0… @IAP_Sydney @KirbyInstitute @ProfStephenKent
This is super important. Severe COVID is THE major issue today. Neutralising antibodies protect against severe COVID.
Do you like your covid-19 vaccines to give you a good dose of neutralising antibodies? You should because we've shown they correlate not only with protection from symptomatic but also severe disease! Another great collab with @DebCro nature.com/articles/s41467-0…
Stephen Kent retweeted
Research Highlight rdcu.be/c8pFw on a paper by Juno and colleagues that examines T cells frequency and phenotype after Delta and Omicron breakthrough infection in previously vaccinated individuals.
Crazy strong link between Nab and protection from severe COVID, p <2.2e-16. Superb work by @DebCro, the Davenport group and collaborators. @KirbyInstitute @TheDohertyInst medrxiv.org/content/10.1101/…
Stephen Kent retweeted
Our latest preprint shows that neutralising antibodies predict protection from severe COVID-19. Great collaborating with @ProfStephenKent @m_steain on this important work from the @KirbyInstitute medrxiv.org/content/10.1101/…
More brilliant work from David Khoury and team. Elegantly reconciles protective immunity by Nab from multiple angles.
Correlates of protection, thresholds of protection, and immunobridging in SARS-CoV-2 infection medrxiv.org/content/10.1101/…
Stephen Kent retweeted
On paper on immune dysfunction during #longCOVID
is now publish @NatImmunol.
@DavidDarley_ @Dan_B_Wilson @GregDore2 @KirbyInstitute @KentLaboratory @TheDohertyInst
nature.com/articles/s41590-0…
Nervous about the ability of new vaccines to combat COVID variants. Our immune systems can recognise the old strains better than the new ones, called "immune imprinting". Discussion piece out in Trends in Immunology. doi.org/10.1016/j.it.2021.09… @WheatleyAtotheK @scientist_JJ @Hyonxhi
Super proud of Jen, Hyon-Xhi and Amy on the announcement of their NHMRC Investigator awards. Richly deserved in a crazy crazy tough system. Allows them to dream even bigger. Will be exciting to watch over the next 5 years. Congrats @scientist_JJ @Hyonxhi @AmyWChung
Congratulations, especially to Adam and the team @KentLaboratory
We are making antibody cocktails against #COVID19 !! 🙏 #MRFF funding to manufacture monoclonal antibody treatments into clinical trials. Great collaborative outcomes between @WEHI_research @TheDohertyInst @BurnetInstitute @KirbyInstitute @CSL AffinityBio and @CSIRO
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The Kent lab is hiring! We're looking for a project manager to help co-ordinate our recently funded next-generation COVID-19 clinical vaccine development project 💉
doherty.edu.au/news-events/n…
More information and application below 👇
jobs.unimelb.edu.au/caw/en/j…
Wonderful zoom meetings of our NHMRC program grant over the last 3 days. Great science and discussion. So fortunate to have the insights of Prof Ranjeny Thomas. Pity we couldn't meet in person but...one day. Jane Batten amazing at keeping us organised.
Our @KentLaboratory team has been busy over the past few months! Excited to share some of the stories to which we've contributed, with preprints now online.
1) Super proud of this work with the Davenport and @TricckyLab groups
doi.org/10.1101/2021.08.11.2……
2) We have a fantastic collaboration with Gail Matthews, @c_phetsouphanh, Tony Kelleher and colleagues at @KirbyInstitute on Long Covid doi.org/10.1101/2021.06.01.2…… They describe long term immunologic dysfunction following even in mild COVID. Get vaccinated and stay safe people.
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3) We've been happy to contribute the validation and testing of rapid neutralising antibody tests for COVID-19 with David Anderson, @ProfDaleGodfrey and teams at @BurnetInstitute and @TheDohertyInst.
medrxiv.org/content/10.1101/…
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Great collaboration with @Kev_in_Science and @AmyWChung on antibodies to COVID in tears and saliva just up on medRxiv. Eye protection everyone!
medrxiv.org/content/10.1101/…
Happy to share our preprint detecting #SARSCoV2 antibodies in plasma, saliva and tears from convalescent individuals with mild #COVID19 (7 months) and also #PfizerBioNTech vaccinees (2 weeks post-2nd dose) (1/4)
medrxiv.org/content/10.1101/…
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