Prometheus Laboratories retweeted
Correction: Infant less than mom!
Risankizumab, IgG1, has lower than expected placental transfer rates with infant > mom. @MLongMD @PIANOIBD @UCSFHospitals Low Placental Transfer Rates of Risankizumab Among Pregnant Women With Inflammatory Bowel Disease academic.oup.com/ibdjournal/…
Prometheus Laboratories retweeted
pubmed.ncbi.nlm.nih.gov/3759…
Proud of the collaboration @prometheuslab. Important work in assisting with drug selection and personalisation of care in IBD.
Prometheus Laboratories retweeted
The relationship between endoscopic healing index, fcal and mre. Great work. By @EmilySSmithMD !
pubmed.ncbi.nlm.nih.gov/3764…
@Dana_Lukin @DCharabaty @IBDimmunology
Prometheus Laboratories retweeted
Lawrence et al compared standard induction with #IFX vs optimized induction in #children with #IBD finding that optimized induction was associated with ⬆️ odds of achieving long-term clinical remission.
bit.ly/3ESKfo0
Prometheus Laboratories retweeted
Proactive infliximab optimization during induction guided by a pharmacokinetics dashboard improves IFX durability and immunogenicity. <8% of pts were ADA ➕ by end of induction & most ADAs were transient. bit.ly/3RDarI3
Prometheus Laboratories retweeted
#ACG2021
🔺Is the risk of anti-drug antibodies (ADA) inevitable in + HLA-DQA1*05 #PANTS?
@pedsIBDdoc shows that
💎Achieving target drug level at 🔑induction🔑 can overcome HLA-risk of ADA
💎Proactive #TDM at induction can replace need for combo Rx w TNFi to prevent ADA
Prometheus Laboratories retweeted
Impact of Thiopurine Exposure on Immunogenicity to Infliximab Is Negligible in the Setting of Elevated Infliximab Concentrations | Inflammatory Bowel Diseases | Oxford Academic academic.oup.com/ibdjournal/…
Prometheus Laboratories retweeted
More data supporting #tdm in #ibd for tnf antagonists and ustekinumab
onlinelibrary.wiley.com/doi/…
@waqqasafif @IBD_FloMD @guthealthmd @DCharabaty
Prometheus Laboratories retweeted
Serum Ustekinumab Concentrations are Associated with Remission in Crohn’s Disease Defined by a Serum-Based Endoscopic Healing Index | Crohn's & Colitis 360 | Oxford Academic @guthealthmd @waqqasafif academic.oup.com/crohnscolit…
















