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Training containment plan for an ASI. Likely wouldn't work for models far beyond Astra, though. Feel free to iteratively improve it.
hirosakuraba.github.io/asi-e…
Ben Schulz retweeted
We are announcing three new discoveries in mathematics, computer science, and physics about harmonic analysis, complexity theory, and quantum field theory.
openai.com/index/building-sc…
Ben Schulz retweeted
Now in the October issue of @NatureProtocols: our wildDISCO protocol 🔬
Whole-body immunolabeling, DISCO clearing and 3D imaging of entire mice at cellular resolution with standard IgG antibodies, ~4 weeks start to finish.
Whole-mouse innervation 👇🏻
doi.org/10.1038/s41596-026-0…
Ben Schulz retweeted
At @lanyon_ai, we’re completing Hilbert’s (other) dream.
From November 1st, we’re rolling out pre-release versions of Lanyon to early customers and testers, and will be hosting simultaneous public demos of Lanyon capabilities in San Francisco and Chicago.
From moon bases to modular reactors to atomic-scale programmable matter, we're on a mission to make the abstract concrete, to make the digital physical, and to formally verify reality. Join us!
Ben Schulz retweeted
When you knock out a gene in a tissue, the effect starts in the perturbed cells and extends into their neighborhood. The same knockout can produce one response in a tumor core and another at a tissue border
CONCERT is a generative model that predicts how perturbation effects propagate across tissue
biorxiv.org/content/10.1101/…
Cells in a tissue act in concert, and CONCERT predicts how the whole ensemble responds when one player changes its part 🧵
Ben Schulz retweeted
new #preprint! @niroshajmurugan
Does the brain know what's going on in a limb amputation wound - whether there's a pro-regenerative intervention or not? Let's look at its gene expression levels, with and without our biodome:
"Limb-localized induction of regeneration reshapes brain and amputation-site transcriptional states in adult Xenopus laevis"
biorxiv.org/content/10.64898…
yes, it knows. Also, lots of interesting transcriptional responses both in the limb and in the brain. Plenty of leads for subsequent investigation.
Ben Schulz retweeted
AI doesn't hear the world like people do. In fact, AI doesn't hear the world like other AI.
Across 24 speech recognizers, phonemes were easiest to read out at 21% of encoder depth in Conformers on average, vs 49% in Transformers.
Catch my presentation tomorrow at EMNLP.
Ben Schulz retweeted
Final version is out:
onlinelibrary.wiley.com/doi/…
"Reservoir Computing for Pattern Recognition and Time-Series Prediction Based on Nanofluidic Negative Differential Resistance"
Ben Schulz retweeted
Ever wonder if eventually cells could be trained out of disease states? We're on the path; first steps:
New #preprint - @WesleyPClawson
"Goal directed closed-loop training of network bursts in cortical cultures produces improved performance and error correction over days"
biorxiv.org/content/10.64898…
Our review of Bayesian efficient coding as a theory of perception is out now in TICS – with Ivan Tomić and Máté Lengyel. cell.com/trends/cognitive-sc…
Ben Schulz retweeted
New paper!
How do you get a model to tell you something that it doesn't want to?
To study this we trained models that sandbag: they intentionally underperform, here by hiding code vulnerabilities they have found, from their overseer
🧵
Ben Schulz retweeted
Dendritic computation for cognitive flexibility
Our new paper in Science identifies rule-belief signals in the distal apical dendrites of cortical pyramidal neurons. These signals integrate with somatic sensory signals to support flexible decisions.
science.org/doi/10.1126/scie…
Ben Schulz retweeted
Ok folks, informal poll: use the little browser app at the link below to say how you think the sets of physical systems, living beings, and minds fit together in a Venn diagram:
three-circles.space.fast/
Ben Schulz retweeted
Dopamine and acetylcholine act as high-dimensional reconfiguration signals that alter the statistical architecture linking neuronal functional properties, not just individual computations. This work demonstrates that neuromodulation reshapes the information transfer between excitatory and inhibitory cells in mouse somatosensory cortex, revealing how receptor-specific signaling restructures circuit-level computation.
pnas.org/doi/10.1073/pnas.26…
Ben Schulz retweeted
Our new paper led by Ida Mattsson on the game-theoretic limits that an assistant faces when trying to be both helpful and not harmful, when it doesn't know who it is talking to.
arxiv.org/abs/2610.27373
Ben Schulz retweeted
Over the past year, the Discovery team at @GoogleDeepMind, in a project led by student researcher @dsantosmarco, has made new discoveries in one of the most beautiful open problems at the edge of computation: Finding the 6th Busy Beaver (BB) number.
While most AI math systems solve human-generated problems, like theorems, this work tackles a different aspect of mathematical creativity: Discovering hidden problems.
For years, the BB Community has pursued one of theoretical computer science’s most captivating collaborative quests: finding the simplest programs that run the longest before halting. Because determining whether these programs ever stop is uncomputable, no universal algorithm can solve it, meaning new mathematical techniques need to be found and invented to make progress.
In this way, the BB challenge serves as an open ended domain for mathematical creativity and, in particular, a generator of hard math problems called Cryptids. These are tiny programs whose halting behavior is governed by and equivalent to deep, unsolved math problems in number theory, similar to the Collatz or Goldbach conjectures. Historically, the BB community had recognized ~20 Cryptids in BB(6), and the best problems were selected for the Busy Math Olympiad (BMO).
Building on their work, Marco built a pipeline powered by Gemini 4 Argon that:
1️⃣ Simulates raw Turing machine traces to compress recurring patterns.
2️⃣ Conjectures mathematical transition rules & runs synthetic experiments to test edge cases.
3️⃣ Proves the equivalence formally in Lean 4.
Using this pipeline, Marco and the team discovered 20 new potential Cryptids and verified 33 more machines previously studied in the BB community. All the proofs were open sourced and shared in the community discord channel and we hope that they will help the community to make progress towards resolving BB(6). We also contributed related halting/non-halting proofs directly to the community GitHub repository.
Finding these Cryptids shows hidden links between simple programs and number theory, and helps mathematicians map the limits of computation. I'm also excited about Gemini 4 Argon's ability to help researchers both solve hard problems and accelerate scientific discoveries, of which Busy Beaver is just one example.
Work led by our student researcher @dsantosmarco with paper contributions from @vivek_veeriah, @Dahoas1 , Andrew Bolt, @zuza777 , Satinder Singh, and myself with additional contributions from Hussain Masoom, @maxencefaldor , @MoritzFirsching and Petar Sirkovic.
Read more about it in our paper: arxiv.org/abs/2610.22603
Ben Schulz retweeted
1/ Two really fun reviews just landed back to back in Current Biology, both on a question I never get tired of: why did animals take over when they did? One argues animals engineered their own world. The other argues oxygen and temperature had to line up first.
I pre-emptively disconnected ALL my sites / VPS servers from the web
I'll wait for the patch to hit at 2 PM UTC
If you have a PHP website, probably good to take them down until you patch PHP
69.3% of the web runs on PHP so this is going to be intense!
Good time maybe to buy cybersecurity stocks? (not financial advice)
Ben Schulz retweeted
How should an agent decide where to explore, given unlabeled offline data? 🤖
In our new paper, we show that empowerment, a measure of how much control an agent has at a state, can be estimated from offline data and used to guide exploration!
ishirgarg.github.io/offline-…
(1/7)
Ben Schulz retweeted
“One of the worst things that slows down progress is the concept of 'emergence.'”
This week on 632nm, @drmichaellevin (@TuftsUniversity) argues that the concept of emergence can hold science back by treating unexpected biological behavior as an explanation rather than something to investigate.
“Emergence just means surprise... You didn’t see it coming.”
If we call something “emergent,” we still need to explain why this behavior emerged instead of another. The goal should be to understand the underlying patterns well enough to predict and control them.
We discuss how this perspective could reshape biology, our understanding of intelligence, and AI.
Full episode on X and YouTube (see comment).
Timestamps:
00:00 - Intro
01:16 - Platonic Space
03:55 - Biology in the Absence of Evolution
21:11 - Extracting Knowledge from Platonic Space
37:04 - Development and Loss Functions
50:09 - Investigating Layers of Control
55:35 - Is Computer Science Misleading Our Understanding of Minds?
58:14 - Bioelectric Patterns and Drug Discovery
1:04:07 - How to Build a Predictive Developmental Model
1:13:20 - Levin’s Top Books, Thoughts on Collective Existence
1:18:00 - Questions that Keep Michael Up at Night
1:22:32 - How Does Levin Interact with AI?
Ben Schulz retweeted
You've watched the planet change in Google Earth Timelapse. Now you can build with the imagery behind it in the Earth Engine Data Catalog.
For the first time, all 39 annual global mosaics from 1984 to 2022 are open data, alongside the full methodology
Read the full announcement : goo.gle/4zMwUIT
























