Professor in #Genomics @Sorbonne_Univ_. Interested in omics, core facilities management, bioinformatics and time organization methods.
Paris, France
Joined August 2017
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Stéphane Le Crom retweeted
Reliable, fully local RAG agents with Llama3
With the release of Llama3, there's high interest in agents that run reliably & locally (e.g., on your laptop).
Here, we show to how build reliable local agents using LangGraph and Llama3-8b from scratch.
As a example, we combine ideas from 3 advanced RAG papers (Adaptive RAG, Corrective RAG, and Self-RAG) into a single control flow in LangGraph.
We run this locally w/ open source embeddings c/o @nomic_ai, @trychroma vectorstore, @tavilyai for web search, and Llama3-8b via @ollama.
Code:
github.com/langchain-ai/lang…
Video:
youtu.be/-ROS6gfYIts
Stéphane Le Crom retweeted
Accessible #ResearchInfrastructures are key for fostering Europe’s innovation potential!
For the latest #HorizonEU INFRA call, we’ve received 163 research proposals with a requested budget of €1,038 billion💶
32 projects are expected to be funded🤝🏻
🔗 europa.eu/!XbQg4w
ALT A visual with a blue background and a microscope. It shows the received number of proposals and the corresponding budget requested for the three calls.
Stéphane Le Crom retweeted
🤖 So #ChatGPT wrote the first sentence of this @ElsevierConnect article. Any other parts of the article too? How come none of the coauthors, Editor-in-Chief, reviewers, typesetters noticed? How can this happen with regular peer-review? pubpeer.com/publications/CAA…
ALT https://pubpeer.com/publications/CAABBF887348FB2D1C0329E0A27BE6
Stéphane Le Crom retweeted
Finally out!
“Challenges and perspectives in computational deconvolution of genomics data”. Kudos Drs Garmire, Teschendorff & team!!
🙏🏼@GarmireGroup for including me. @naturemethods for publishing!
nature.com/articles/s41592-0…
Stéphane Le Crom retweeted
A paper in Nature group on the use of nanopores for single-molecule proteomics sequencing. This would still be a challenge for complex samples, but a step forward in the use of nanopores for #NextGenProteomics nature.com/articles/s41592-0…
Stéphane Le Crom retweeted
First TurBOT shipped and ready to go.
You'll be able to hear more about TurBOT at #ECCMID2024 and at London Calling 2024 (#nanoporeconf).
Learn more about TurBOT here: bit.ly/48N8oJI #WYMM
Stéphane Le Crom retweeted
The #ESFRI Landscape Analysis is now complete! Today the 87th Forum approved the #LandscapeAnalysis report, expected to be published by the and of May 2024
Read more about the LA process & the contributions of #ESFRIStakeholders👇
esfri.eu/landscape_analysis
#ResearchInfrastructures
Stéphane Le Crom retweeted
iconPCR: Super-Flexible qPCR Thermocycler Oft Dreamed, Now Delivered
#AGBT24 launch of N6 Tec iconPCR has me very excited
omicsomics.blogspot.com/2024…
Stéphane Le Crom retweeted
Researchers at the @CityUHongKong have used @nanopore direct #RNAsequencing to evaluate 10 computational tools developed for studying modifications on viral #RNAs. rna-seqblog.com/researchers-…
Stéphane Le Crom retweeted
#CTLS is pleased to announce that applications are now open for the 2024 CTLS Professional Development Course for #CoreFacility Staff.
ctls-org.eu/ctls-professiona…
#corefacilities #ProfessionalDevelopment #sharedresources #technologyplatforms
Stéphane Le Crom retweeted
I have updated the #NextGenSequencing specs for the @UltimaGenomics UG100 instrument, which a "deli-fridge" sized competitor to the $ILMN Illumina NovaSeqX "fridge-freezer" sequencer. Single-end median 300bp, 6Tbp 12h run, ~20,000 hg30x/year, $100/genome. bit.ly/ngsspecs
Stéphane Le Crom retweeted
Correcting myself about the Oxford @nanopore P2/P2 Solo: this is only for PromethION flowcells. So the smallest combo covering all flowcell sizes currently is: MinION Mk1b (USB-C version) and P2 Solo.
Stéphane Le Crom retweeted
📣 @Sorbonne_Univ_ has unsubscribed from Web of Science.
👉 A proud leader in #openscience, our university continues its commitment to open research information and is exploring new, participative tools: sorbonne-universite.fr/en/ne…
Stéphane Le Crom retweeted
Direct RNA continues to improve. RNA004 provides improved accuracy (96%) & 3X output over RNA002.
6mA in RNA detected at 98.95% accuracy. New software enables accurate poly(A) tail length prediction.
Short RNA (<50bp) & m1 pseuodridine basecaller coming soon. #nanoporeconf
Stéphane Le Crom retweeted
Isosceles: Accurate long-read transcript discovery and quantification at single-cell resolution with Isosceles biorxiv.org/content/10.1101/…
Stéphane Le Crom retweeted
Today at the 8th workshop of @fr_genomics in Lille, Oumy Seydi from our platform is presenting our latests tests of new kits for low-input #RNAseq
