#BLM #sarcoidosis Prof of Med/ID😎; student of patients; SimPlot author; Tweets only as self (he/him)

Baltimore, MD
Joined July 2010
"Knees or trees, either way you're still lynchin' me..." Powerful all the way through. Thank you @AfricanaCarr. Thank you @NickCannon. I'm listening, humbly.
Our Brother @NickCannon just returned from Minneapolis-St. Paul, where he was in the street, shoulder to shoulder with the people. His reflection here places this moment in it's necessary context: youtu.be/8BXwd_rald8 #GeorgeFloydProtests #JailbreakTheBlackUniversity
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Stuart Ray retweeted
Every Sunday night prior to clinical service week, I have a flutter in my heart. Mix of nervousness/excitement/anticipation. Been the case despite doing this for more than a decade. It’s an honor and a responsibility to take care of patients. This is not a job but a way of life!
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Replying to @_jasonwei
Great post…thanks for sharing your thoughts. If I may opine on this as a radiologist with some technical understanding of LLMs/VLMs: I agree radiologists will not be automated away anytime soon. Your elastic demand point is mostly right (some modalities impart ionizing radiation so there is a good reason to not scan as frequently as you want), and I’d add a more fundamental one. The current transformer-based AI algorithms are extremely sample-inefficient compared to humans, especially when it comes to vision tasks (as opposed to text-based tasks). When I was a radiology resident, I read maybe 3000 CTs of the chest, abdomen and pelvis to reach expert/attending level. I can also make a rare-disease diagnosis after having seen 1 example study (or none; I can make a real-life diagnosis purely from reading and seeing an example case from a textbook). Currently, the best radiology VLM models, such as Nvidia’s NV-Reason-CT model, do not reliably call even some of the most common pathologies, despite having trained on >70,000 CTs that surely contain many examples of a common finding (macro-F1 of 0.614). I can think of several reasons for this: these models usually leverage weakly supervised learning such as CLIP, pairing radiology reports with the images, since wide-scale expert annotation is impractical for every study for every finding (Radiology’s Bitter Lesson, if you will; however, the signal that can scale is the noisy one). To scale, the model(s) will need to learn to associate image findings with words in the radiology reports. However, using radiology reports as ground truth can substantially limit learning. (1) As any radiologist will tell you, we don’t mention everything that we see. Otherwise, your radiology report would be like 30 pages long and not clinically useful. We mostly call the things that matter (for the most part). Sometimes, we don’t even call things that matter. Thus, some reports may mention “diverticulosis” when there is diverticulosis, while other reports don’t, even if there are findings of diverticulosis in the images. (2) Another limitation is that the actual real ground truth is never confirmed, which I suspect is a much bigger problem and harder to correct. When I was a radiology resident, I saved many cases in which my attendings and I made a certain call, and I was curious if those were correct. Right before I was about to graduate, I checked every case I had logged. Many calls were incorrect (and I trained at a major academic center in which subspecialized radiologists read their part of the body, so the attendings making those calls are above-average radiologists; real-world data is likely much worse). (1) and (2) make training very difficult when there is so much incorrectness, ambiguity and noise in the training data. The above observations are pretty self-evident when you look at other vision tasks, such as self-driving, for which there is (1) ample data with predominantly correct actions (labels), and (2) known ground truths (the task of driving is, for the most part, unambiguous. You see a red light, you stop. You want to make a left turn? You signal and yield to passing cars before turning. Those are universally agreed-upon “correct” actions). To use Tesla FSD as an example: even with the best compute, engineers and data, it took over a decade to reach limited, geofenced driverless service. And this is despite the fact that driving has a much shorter tail than radiology does. Further, self-driving usually has one correct action at a time. In radiology, that’s not true. There are so many different radiological appearances of one disease, as well as the same appearances of different diseases. And various diseases can involve the same anatomical location (for example, look up adrenal collision tumor). To “automate radiology” is also a huge simplification. The vast breadth of radiological studies is seldom mentioned. For a single modality of a body part, there are so many different variants. Say, for example, CT of the abdomen and pelvis: there are at least 10 different flavors of this. To name a few, there is the non-contrast CT, the portal venous phase CT (bread-and-butter workhorse), and then there are specialized versions such as the liver mass protocol, CT angiogram GI bleed protocol, pancreatic mass protocol CT, adrenal mass protocol CT, kidney mass protocol CT, and CT urogram, each of which contains 3-4 phases and is tailored to answer a specific question. All of this is just one modality for one section of the body. Now do ultrasound, X-rays, gamma studies, PET studies, and MRI. And then consider all the other body parts (brain, head and neck, chest, etc.). I’ve only touched upon the surface of all the nuances, but I think the current capability gap and your demand argument point the same way: radiologists will be busy for a long time.
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Morning Read: Implementation of integrated hepatitis C test and treat with peer support in opioid treatment programs: A qualitative RE-AIM evaluation of staff perspectives pubmed.ncbi.nlm.nih.gov/4273…
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Congratulations to Dr. Annie Antar on her recent promotion to Associate Professor!
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Stuart Ray retweeted
Taking a look at some recent vaccine recommendations. Some hits, some misses. And a hope for better data to inform these decisions. Free to read link in replies. @NEJM @NEJMClinician
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IDeas magazine article: The study of HIV has produced major advances in patient care over the last four decades, and Francesco Simonetti sees plenty of room for meaningful progress, from deeper understanding of basic virology to novel clinical outcomes. hopkinsmedicine.org/news/art…
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Join Dr. Matthew Hamill for HIV Foundations Virtual Office Hours, a session for practitioners w/limited experience in HIV treatment & prevention to improve competence in incorporating best practices into patient care, today and in the future. Learn more: deceraclinical.com/education…
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Stuart Ray retweeted
Why does @NIH conduct international research? Not as foreign assistance, but because it advances science and the health of all, including Americans. In @Health_Affairs, I highlighted 5 ways international research advances NIH’s scientific mission.
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Stuart Ray retweeted
Florida officers found two middle school students had guns, bombs, Nazi symbols, and a screed on demographic replacement that incited many mass shooters, including in El Paso and Buffalo. These mass shooters have imagined a political plot to mass murder White people, deputized themselves as defenders, and engaged in mass murder. None of these shooters were 14 and 13-years-old, making this averted terror attack unique. And uniquely chilling as Islamophobia surges. These shooters are seemingly getting younger and younger. Two shooters, 18 and 17, killed three people at the Islamic Center of San Diego in May. And now 14 and 13 in Florida. The most dangerous political theory of our time—great replacement theory—is spreading deeper into human consciousness. This is the predictable outcome of politicians pushing this theory and removing antiracist education that protects youngsters from ingesting the myth that Black and Brown people are coming to take over. My latest at The Emancipator. theemancipator.org/2026/08/2…
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Congratulations to Christine Durand on her well-earned promotion to Professor! 👏👏👏
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ID in the News: Thoughtful commentary from @ChidaNatasha on the role of AI in medicine in @TIME "We need to embrace what AI can do to make medicine better while at the same time recognizing what it cannot do." time.com/article/2026/08/15/…
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Morning Read: Inhibitory potential of autologous neutralizing antibodies sets quantitative limits on the rebound-competent HIV-1 reservoir pubmed.ncbi.nlm.nih.gov/4239…
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Steve Kirsch claims VAERS shows COVID vaccines killed 676,000 Americans—roughly 1 death per 1,000 doses. VAERS cannot support that calculation. In KIRSCH PICKING, we examine how assumed multipliers and incomplete datasets become confident but unsupported conclusions. 🧵
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Morning Read: Prevalence of Hepatitis B Coinfection in People With HIV by Birth-Year Cohort pubmed.ncbi.nlm.nih.gov/4250…
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Naturopaths and homeopaths never have recalls, because they have no quality control.
🚨Common Thyroid Drug Recalled Nationwide Read more

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