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W-18 grows less concerning by the day. Fentanyl not so much. nitter.gq/zenbrainest/status/734…
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Confronting the stigmatizing language of addiction tandfonline.com/doi/pdf/10.1… @SubstanceAbuseJ HT @StefanKertesz
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ICYMI... nitter.gq/davidjuurlink/status/7…
1. Some clever reporters went through thousands of pages of confidential @purduepharma documents nitter.gq/DavidJuurlink/status/7…
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6. And once W-18 was confirmed, why the delay in notifying the public? Fair question for Minister @shoffmanAB and @GoAHealth
/ end
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5. More important question: Why did @HealthCanada take 4 months to identify powder seized in December as W-18? theglobeandmail.com/news/alb…
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4. Bottom line: The potency of W-18 relative to fentanyl is unknown, and the answer to this question is "Not very" nitter.gq/forensictoxguy/status/…
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3. Thing is, these numbers derive from a mouse model (phenylquinone writhing test) and aren’t specific to opioids nature.com/nature/journal/v2…
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2. Estimates of W-18 potency derive from its 1984 patent 1.usa.gov/1STYNSU Key table below, via @mevansbrown
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1. Some observations about W-18, the bionic opioid all over the news, said to be 100x more potent than fentanyl calgaryherald.com/news/crime…





