IISER Berhampur is inviting applications for Ph.D. admission for the January 2027 session!
If you are interested in joining us on this exciting journey, please apply by 24 October 2026. Details: iiserbpr.ac.in/admissions-ph…
Tapas Paul retweeted
How do you make reading DNA faster, cheaper and scalable enough to transform medicine?
That question sits at the heart of the breakthrough behind the 2026 Wolf Prize in Chemistry, awarded to Pascal Mayer, Shankar Balasubramanian and David Klenerman.
Their work helped turn DNA sequencing into a massively parallel process, dramatically reducing the cost and time needed to read genetic information, and helping make large-scale genomics possible.
But what does that actually mean? How does next-generation sequencing work, and why was this such a major leap forward?
Watch the video to see the science behind the breakthrough and understand how three researchers helped change the way we read the human genome.
@Cambridge_Uni
Check out our @NatStructMolBiol comment on non-equilibrium phase separation! We highlight how metastable nanoclusters and RNA dynamics serve as key intermediates shaping condensate formation, stability, and function.
nature.com/articles/s41594-0…
Collaborative work published in Neuron! Proud to be part of this study uncovering new insights into the molecular mechanisms underlying cellular organization.
C9orf72 hexanucleotide repeat RNA drives transcriptional dysregulation... sciencedirect.com/science/ar…
Tapas Paul retweeted
Defining RNA oligonucleotides that reverse deleterious phase transitions of RNA-binding proteins with prion-like domains: Molecular Cell cell.com/molecular-cell/full…
Happy to share our latest research published in Nature Communications!
“ FUS nanoclusters are a distinct within the dilute phase”
nature.com/articles/s41467-0…
Tapas Paul retweeted
Structural basis for dual DNA and RNA specificity of the G-quadruplex-... sciencedirect.com/science/ar…
Thanks TJ @taekjip for giving me the opportunity to work on this,
“Mechanistic insights into direct DNA and RNA strand transfer and dynamic protein exchange of SSB and RPA”academic.oup.com/nar/article…
Tapas Paul retweeted
Fun study led by Sam Sanford @glowingtelomere, Samuel Johnson and Tapas Paul. G-quadruplex antibody BG4 promotes folding of G-quads containing destabilizing G mutations or damage. academic.oup.com/nar/article…
Tapas Paul retweeted
Switch-like compaction of poly(ADP-ribose) upon cation binding | Proceedings of the National Academy of Sciences pnas.org/doi/10.1073/pnas.22…
Tapas Paul retweeted
Please retweet! We invite applications for NIH-funded job opportunities in #KudryashovLab from enthusiastic biochemists, biophysicists, cell & structural biologists. Knowledge of the actin cytoskeleton is a plus. Passion for scientific research is a must.
Tapas Paul retweeted
The study is now published in NAR. Congrats to all authors!🎉 Special kudos to the amazing @b_subhas and Pim America, the 2 first authors of the article, and collaborators Anssi Malinen @UniTurku and Martin Depken @tudelft. @VU_Science @UniFAU
academic.oup.com/nar/advance…
Our new study on bacterial #RNAP open complex dynamics is out on @biorxiv_biophys! We used high throughput #magnetictweezers to characterize the first step in bacterial #transcription initiation. @FAU_Germany @VUamsterdam @MPZ_PhysMed
biorxiv.org/content/10.1101/…
What we found:
1/12
Tapas Paul retweeted
Vectorial folding of telomere overhang promotes higher accessibility academic.oup.com/nar/advance…