188 inhibitors across 210 #kinases. A product of #openscience, inspiring the discovery of pioneer medicines
Chapel Hill, NC
Joined May 2015
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A collaboration with UNC virologists using @therealKCGS led to this —> uncnews.unc.edu/2022/05/20/u…
Host kinase CSNK2 is a target for inhibition of pathogenic β-coronaviruses including SARS-CoV-2 biorxiv.org/content/10.1101/…
An ATP-competitive kinase inhibitor with exquisite selectivity. How? Read on....@thesgconline @DruggableGenome pubs.acs.org/doi/10.1021/acs…
Best Kinase Inhibitor Set. Ever. retweeted
Cheryl announcing #Target2035 webinar series at today’s kick-off meeting. Looks exciting! @CherylArrowsmi1
With our friends at Promega we built the first map of CDK drug selectivity in live cells across the whole family: CDK1-20 #openscience #chemogenomics
nature.com/articles/s41467-0…
Best Kinase Inhibitor Set. Ever. retweeted
A group of us around the world are creating an #openscience non-profit to invent drugs explicitly to put on the shelf for the next pandemic. We started the project last summer, but should have started a decade ago…damn. Announcement this week or next. @thesgconline
Best Kinase Inhibitor Set. Ever. retweeted
Researchers at @UNCpublichealth are testing an antiviral drug that shows promise as a possible treatment for COVID-19. #UNC’s Ralph Baric heads the lab developing the broad-spectrum antiviral that could potentially provide relief to the global pandemic unc.live/2ISOsM0
Round table discussion at PharmSci 2020 about the social and economic impact of #openscience @UNCPharmacy
Best Kinase Inhibitor Set. Ever. retweeted
Discover a new #Kinase Chemogenomic Set from @therealKCGS ximbio.com/reagent/157681/th… #datasheet #lifesciences #reagents #inhibitors
Best Kinase Inhibitor Set. Ever. retweeted
Proud to announce today an expansion of our partnership with @ChordomaFDN to accelerate drug discovery in an open-source way! CC: @dhdrewry @UNCPharmacy @ICR_London @PaulWorkmanICR @thesgconline chordomafoundation.org/lates…
Best Kinase Inhibitor Set. Ever. retweeted
Together with @TheMarkFdn, we are proud to announce a two-year, $1.4M grant to researchers @PaulWorkmanICR @dhdrewry @Ogileadi focused on creating the first drugs capable of targeting #brachyury, the Achilles’ heel of #chordoma chordomafoundation.org/lates…
Want to learn how #openscience will lead to affordable medicines? Come to the #pharmsci2020 symposium @UNCPharmacy in Chapel Hill on Tuesday #SGC-UNC #drugdiscovery wraltechwire.com/2020/02/27/…
Best Kinase Inhibitor Set. Ever. retweeted
ICYMI: Check out the Kinase Chemogenomics Set (KCGS): 187 inhibitors for 215 kinases. A collaborative resource meticulously developed & curated by the SGC-UNC team. thekcgs.com/ More details here on @biorxivpreprint biorxiv.org/content/10.1101/… #openscience
[Part 2] ...This collaboration has resulted in multiple publications and grant funding as a specific result of these interactions. - Lee Graves, PhD, Professor in Department of Pharmacology @UNC_SOM Read more about Dr. Graves and his KCGS Collaboration --> theKCGS.com
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[Part 1] My lab and I have greatly benefited from using KCGS in investigating cellular mechanisms of drug resistance in cancer by the application of chemogenomic libraries to discover novel kinase targets for pancreatic cancer treatment...
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We are proud to work with @boehringerus and their #OpnMe platform to encourage open collaboration between scientists! Check out the work they do at OpnMe.com and become a part of the KCGS open science community at theKCGS.com!
We are proud to contribute to @therealKCGS’s #openinnovation initiative by donating 17 kinase inhibitors to their Kinase Chemogenomics Set. Learn more on #opnMe: bit.ly/2ShIw4N
We are grateful for the collaboration we share with @Boehringer and the #opnMe team!
We are proud to have donated 17 kinase inhibitors to the #OpenInnovation initiative Kinase Chemogenomics Set. Kudos to @therealKCGS from the #opnMe team
Thanks to @UNCPharmacy for helping make #KCGS available to the world
#DYK: the first Structural Genomics Consortium lab to operate in the US is located in #UNCPharmacy? Thanks to support from the Eshelman Institute for Innovation, Tim Willson & his team's research is placed in the public domain for use, no strings attached bit.ly/2tOTGo5
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Best Kinase Inhibitor Set. Ever. retweeted
#DYK: the first Structural Genomics Consortium lab to operate in the US is located in #UNCPharmacy? Thanks to support from the Eshelman Institute for Innovation, Tim Willson & his team's research is placed in the public domain for use, no strings attached bit.ly/2tOTGo5