Shrikant Mantri

Looking forward to transforming large-scale computation into new biological insights and discoveries! 🤝 Interested in collaboration? DM us to connect!

🚀 Exciting news !! We’re thrilled to share that our team has been awarded compute-time grants on PARAM Rudra! This powerful HPC resource will help us scale up natural product discovery, large-scale BGCs mining, and computational exploration of nature’s chemical diversity. 🌿🔬

🔬 Dissertation themes 🧬 Metagenome Mining: Discovery of novel biological patterns 🧪 Fungal Siderophore Discovery: Computational exploration and novel patterns discovery Hands-on experience in HPC, genome/metagenome mining, BGC analysis, and natural product discovery.

🎓 Master’s Dissertation Opportunities | January 2027 Mantri Lab, BRIC–NABI is inviting applications from motivated Master’s students interested in computational biology & bioinformatics.

🙌 Thanks to all the authors for their contributions and support! 🙏 Special thanks to Prof. Nadine Ziemert & Martina Adamek for their valuable feedback. 🧬✨

Highlights 1. Identified 277 candidate BGCs across diverse bacterial hosts. 2. Uncovered previously unexplored biosynthetic diversity across benzoxazolinate, benzobactin & ashimide-like BGCs. 3. An MLP-based bioprospecting model enables rapid detection of rare bzoz-like BGCs.

🧵 Our preprint is now live! 🎉 Excited to share our work: “Microbial bioprospecting for benzoxazolinate-like molecules: unleashing the potential of genome mining.” 📄 Read the preprint on bioRxiv: doi.org/10.64898/2026.08.17.…

📢Interested in microbial genome mining, natural products, or bioinformatics? We welcome collaborations on BGX, including beta testing and validation, tool development and integration, novel ideas and use case expansion, etc. #Collaboration #ComputationalBiology #NaturalProducts

3. NPBdetect predicted 417 (ODOG) and 298 (IndeNCBI) high-confidence antibacterial BGCs. 4. Genomic surveillance enables tracking of antimicrobial resistance genes across bacterial genomes. #bioRxiv #GenomeMining #Bioinformatics

📜Highlights: 1. Revealed distinct biosynthetic trends between ODOG and IndeNCBI datasets. 2. Integrated antiSMASH, DeepBGC, and GECCO for comprehensive BGC discovery.

Bacterial Genome eXplorer (BGX) is a computational pipeline for microbial genome analysis, from genome assembly and genomic surveillance to BGC annotation, with a user-friendly, interactive interface for visualising and exploring results. 🌐Visit: bgx.nabi.res.in/

We are excited to share that our manuscript titled “BGX: A Comprehensive Pipeline for Genomic Insight into Bioactivity Prediction, Genomic Surveillance, and Novel Biosynthetic Gene Cluster Assessment” is now available on bioRxiv! 🎉 🔗: biorxiv.org/content/10.64898…

🚀 Looking for a research internship this summer? MantriLab is offering a short-term internship opportunity for motivated students. 📌 Check out the poster for more details. #Internship #MantriLab #ResearchOpportunity #Students

Their research has contributed valuable insights. Congratulations on this achievement, and best wishes for the exciting opportunities ahead! #ResearchLife #MastersStudent #ScientificResearch #LabLife #HigherEducation

We are delighted to celebrate the successful completion of a Master's dissertation by Manvinder Jaswal from our lab. 🎓 Title: Designing an integrative framework for functional annotation and combinatorial ecological inference in microbiome and metagenome studies

Looking for something smaller than the full-scale SMC setup — maybe representative BGCs, clustered BGCs, antiSMASH-only outputs, or a compact indexed version for local pipelines. Would love to know if any community project/GitHub repo exists. @kaiblin @marnixmedema @thinkgenome

Has anyone created a lightweight version of the JGI SMC (Secondary Metabolites Collaboratory) database for faster BGC searches and development? #SecondaryMetabolites #antismash #NaturalProducts #bioinformatics #metagenomics #BGCs