@tinaliu_phd

Assistant Prof of Molecular Bio & Biochem @RutgersCABM | Exploring & Engineering CRISPR-Cas systems | Former @doudna_lab postdoc | PhD @RapoportLab

 Piscataway, NJ
sites.rutgers.edu/tina-liu-lab
Joined November 2020
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  • Followers603
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Our new lab at @RutgersCABM is growing! We are currently recruiting for the following positions: Postdoc: jobs.rutgers.edu/postings/22… Lab Assistant: jobs.rutgers.edu/postings/22… Summer Intern: cabm.rutgers.edu/research/ca… #hiring #CRISPR #biochemistry #postdoc #rutgers #labtech #research
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I am thrilled to share my latest work, out today in @Nature. This project started ~18 months ago as a blueprint for my own lab, which will start at @ISTAustria in July, but not have been possible without the support of @davidwtaylorjr & the whole team nature.com/articles/s41586-0…
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Some good news is coming soon (but still embargoed) - but that means I'm looking for folks to work on a couple new projects. I'm looking for postdocs to push the boundaries of Holographic Optogenetics to understand interactions related to movement. oldenburglab.com/positions
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What limits rubisco function? Is it the chemical mechanism? Evolution? In an updated pre-print @prywes et. al explore this question by assaying >99% of single amino acid mutants in Form II rubisco (1/7)
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Our work on the analysis of Type VI CRISRP-Cas system from L. shahii is published! Upon the target recognition, this system cleaves not the recognized target, but cellular tRNA molecules. science.org/doi/10.1126/scia…

tRNA anticodon cleavage by target-activated CRISPR-Cas13a effector

Leptotrichia shahii Cas13a specifically cleaves tRNAs upon target RNA recognition, thus ensuring antiphage defense.

science.org
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🔬Join the Cress Lab @UCBerkeley @igisci! We're hiring a Research Tech/Lab Manager to lead lab operations & support our research in phage engineering and precision microbiome editing.🧬🦠Apply here to be part of our innovative team! is.gd/4ol7Hj Retweets appreciated!
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My lab is almost set up, and I'm looking for great people to join it! I am currently recruiting a research technician to drive an exciting project on molecular antagonism between bacteria and phage. If you're interested, DM me or apply to this position: wd1.myworkdaysite.com/recrui…
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@RutgersCABM is hiring..... Tenure-Track or Tenured Faculty Positions in Microbiome Studies jobs.sciencecareers.org/job/… #microbiome #faculty @RWJMS @RutgersNB

Tenure-Track or Tenured Faculty Positions in Microbiome Studies - Piscataway, New Jersey

The Center for Advanced Biotechnology and Medicine (CABM) at Rutgers University seeks candidates for two full-time, Tenure-Track...

jobs.sciencecareers.org
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I'm excited to share our findings on a metal-dependent specificity switch for #CRISPR-Cas12a! We profiled the specificity of Cas12a at four Mg2+ concentrations and observed striking differences in mismatch tolerance at lower, physiological conditions 1/n biorxiv.org/content/10.1101/…
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Excited to share our new paper on the ribosome-bound mRNA cleaving CRISPR type III effector protein in @science! science.org/doi/10.1126/scie…

Ribosomal stalk-captured CARF-RelE ribonuclease inhibits translation following CRISPR signaling

A prokaryotic antiviral CRISPR-Cas auxiliary effector cleaves ribosome-bound messenger RNAs to inhibit translation

science.org
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It's out! This paper on phage RNA-mediated activation of bacterial CBASS systems should activate your interest in reading it 🧪🦠🪐📑 @daltonbanh @camgroberts @MarraffiniLab nature.com/articles/s41586-0…
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1/15 Thrilled to share our newest work in @nature! Viruses block CRISPR-Cas immunity using small RNA anti-CRISPRs, a.k.a “Racrs” 😎 nature.com/articles/s41586-0…
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My team at the Innovative Genomics Institute @igisci at Berkeley is looking for a new research associate with histology experience! Consider applying if you’re looking to work with really cool new technologies in the genome editing space. careerspub.universityofcalif…
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CRISPR-Cas13 is tremendously useful for targeting, detecting, imaging, and editing RNA - but we know very little about how it can target structured RNAs, which predominate in nature. (1/19)
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Our story was truly a co-led collaboration between the @doudna_lab and @yimmieg lab! Feeling super privileged to work with such great scientists and bring together so much expertise in genome editing, immunology, and genomics. Check out Jimmie’s great thread below 🧬🧫 – at Berkeley, CA
Jimmie Ye@yimmieg4 Oct 2023
Yay, our collaboration with the @doudna_lab exploring Cas9-induced chromosome loss in T cells, strategies for its mitigation, and implications for T cell therapies is now published in @CellCellPress. Thread 👇doi.org/10.1016/j.cell.2023.…
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Excited to share that I recently started a faculty position in the @RutgersNB MBB dept and the @RutgersCABM! My new lab will explore the fascinating biology of microbial defense pathways and engineer them for applications in human health & medicine. sites.rutgers.edu/tina-liu-l…

Tina Liu Lab @ Rutgers University-New Brunswick

Engineering & Exploring Microbial Defense Pathways

sites.rutgers.edu
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We are currently looking for curious, motivated individuals to join our new lab @RutgersU! Retweets are appreciated. All open positions: sites.rutgers.edu/tina-liu-l… Lab technician opening: jobs.rutgers.edu/postings/21…

Tina Liu Lab @ Rutgers - Contact & Open Positions

Contact info for Tina Liu lab at Rutgers University. Current openings for undergrads, technicians, PhD students and/or postdocs listed here.

sites.rutgers.edu
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🚨 Today, we’re thrilled to share our study expanding the gene editing toolbox to enable virtually any kind of edit in gene transcripts at the order of thousands of bases. A thread 🧵👇(1/n) biorxiv.org/content/10.1101/…

Programmable multi-kilobase RNA editing using CRISPR-mediated trans-splicing

Current gene editing approaches in eukaryotic cells are limited to single base edits or small DNA insertions and deletions, and remain encumbered by unintended permanent effects and significant...

biorxiv.org
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📢 We are hiring! PhD and Postdoc positions available in my new lab at the @MaxPerutzLabs on the @viennabiocenter campus. If you are interested in the mechanisms, functions and applications of transposons, just write me at [email protected]. Please, RT!
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Excited to share our latest story from @doudna_lab systematically studying the phenomenon and mitigation of Cas9-induced chromosome loss in clinical human T cells now on @biorxivpreprint biorxiv.org/content/10.1101/…

Mitigation of chromosome loss in clinical CRISPR-Cas9-engineered T cells

CRISPR-Cas9 genome editing has enabled advanced T cell therapies, but occasional loss of the targeted chromosome remains a safety concern. To investigate whether Cas9-induced chromosome loss is a...

biorxiv.org
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