@tompayne302

Junior doctor | PhD student at the University of Sydney | Anaesthesia & neuroscience research

 Sydney/Melbourne
Joined October 2022
  • Tweets44
  • Following100
  • Followers35
Excited to announce that I have joined the team at RPA Institute of Academic Surgery as the Director of Surgical Nursing Research. Here’s to new collaborations and the future of innovative nursing-led projects!
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Intraoperative hypotension is not associated with reduced atrial fibrillation or hospital length of stay. New correspondence by Payne et al #IOH #hypotension #BP #AF #afib #perioperative bjanaesthesia.org/article/S0…
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👨🏻‍💻🖍️Agree with this correspondence related to @BJAJournals meta analysis on intraoperarive hypotension; all is related to the #POISE3 , where patients spent a median of 0.0 minutes with MAP < 60 mmHg @giovannilandoni @jlvincen @chileanestesia @iceman_ex @Thom_Langer
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Replying to @tompayne302
@tompayne302 presenting on the use of biomarkers in understanding the nature of brain injury associated with delirium and providing a very palatable statistical session. Also on display- his artistic talents - with a sketch of his PhD supervisor @ProfRobSanders #declared2023
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Fibrinogen takes central stage at #declared2023 @tompayne302 and @ProfRobSanders lab.
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@tompayne302 busts biomarker myths around #delirium @ANZDA_delirium #DECLARED2023
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#Statistics thought of the day: Worrying about lack of fit of a statistical model is less productive than assessing (1) the impact of the assumptions and (2) whether a model making fewer assumptions actually predicts future observations better: fharrell.com/post/impactpo
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Peer-reviewed and published today in @NatMentHealth Thank you co-authors, and particularly @SNACCNeuro for seed funding. nature.com/articles/s44220-0…
Boris D Heifets
@TheBorisLab6 May 2023
SPIKED: Stanford Placebo vs Intraop Ketamine Evaluated for Depression. We masked ketamine with surgical anesthesia in depressed patients. Full details now published, peer review pending. Huge antidepressant response in both groups. @TheresaLii 1st auth bit.ly/3LMAueK
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Really cool stuff!
Robert D Sanders@ProfRobSanders12 Sep 2023
Really excited about talking about our new paper showing disturbed feedback cortical connectivity maybe an important mechanism of delirium at the Declared meeting protect-au.mimecast.com/s/B6… @ANZDA_delirium

Delirium is associated with loss of feedback cortical connectivity

INTRODUCTION Post-operative delirium (POD) is associated with increased morbidity and mortality but is bereft of treatments, largely due to our limited understanding of the underlying pathophysiolo...

alz-journals.onlinelibrary.wiley.com
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Subanaesthetic doses of ketamine reduce but do not eliminate predictive coding responses. Are we closer to understanding sensory disconnection? Sanders et al investigate #ketamine #anaesthesia #anesthesia #perioperative bjanaesthesia.org/article/S0…
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FREE TO VIEW. How does female sex impact awareness under anaesthesia? New systematic review & meta-analysis by Braithwaite et al. #anaesthesia #anesthesia bjanaesthesia.org/article/S0…
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Dexmedetomidine in Cardiac surgical Intraoperative Drug Evaluation (DECIDE) trial by Prof Robert Sanders is the latest CTN success story. Congrats Rob on being awarded a $4.1 M @nhmrc grant to run this trial, building on the exceptional track record of the CTN. @ANZCA #CTN2023
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Another manuscript out 🧠🎆 - combining 7T-fMRI and MRS to better understand the role of dlPFC circuits in conditioning-based placebo analgesia. A big thank you to the author team @LukeHenderson_1 @LNSFSydney @vgmacefield @EP_Mills @AimiePeek rb.gy/onfdf

Function and biochemistry of the dorsolateral prefrontal cortex during placebo analgesia: how the...

Abstract. Prior experiences, conditioning cues, and expectations of improvement are essential for placebo analgesia expression. The dorsolateral prefrontal

academic.oup.com
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A Bayesian approach to meta-analysis may better answer the question of whether dexmedetomidine prevents postoperative delirium. Payne et al comment on a recent (frequentist!) meta-analysis by Patel et al #anaesthesia #anesthesia #perioperative bjanaesthesia.org/article/S0…
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Prospective analysis of plasma amyloid beta and postoperative delirium in the Interventions for Postoperative Delirium: Biomarker-3 study by Payne et al @tompayne302 @ProfRobSanders @jentaylorphd bjanaesthesia.org/article/S0… #delirium #amyloid #anaesthesia
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Replying to @BJAJournals
If you want to know more and can come to the Jobson symposium on march 4th - still tickets available @GongGasGirl @JohnLoadsman #bjachat
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Question 5: What should be the role of intraoperative pEEG monitoring in current practice? doi.org/10.1016/j.bja.2022.0… #bjachat
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First up tonight, we discuss connected consciousness after tracheal intubation with @ProfRobSanders bjanaesthesia.org/article/S0… #bjachat

Connected consciousness after tracheal intubation in young adults: an international multicentre...

Connected consciousness, assessed by response to command, occurs in at least 5% of general anaesthetic procedures and perhaps more often in young people. Our primary objective was to establish the...

bjanaesthesia.org
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