We're a genomics company based in Texas. We love DNA and build great apps for the common good. We're hiring!
Houston, TX
Joined October 2020
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Traitwell retweeted
"I would hope it's going to help our children and our grandchildren, and future generations" Hear from our participants Lorraine and Mel on why they're part of UK Biobank.
🧬@UK_Biobank makes a huge contribution to science.
Its research has the potential to detect Parkinson’s sooner, and tackle heart disease.
This week @michelledonelan visited Manchester Science Park to officially mark the future site of UK Biobank’s new £75m centre.
Traitwell retweeted
The first report from the Cancer Programme of the 100,000 Genomes Project, published in @NatureMedicine, presents whole-genome sequencing profiles of 13,880 solid tumors spanning 33 cancer types, providing insights for precision oncology. go.nature.com/4b5PcZW
Traitwell retweeted
The study is one of the first in Asia to examine links between the genomes of mothers, babies and their health go.nature.com/3I1UA3b
Traitwell retweeted
Nice study showing real-world value of polygenic risk scores when integrated with other risk measurements (still work to do on balancing ethnicity of participants - as they note)
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Traitwell retweeted
Great news! You can now browse the #500KGenomes summary statistics for all UK Biobank participants free of charge using our Allele Frequency Browser. The browser was launched on behalf of the Whole Genome Sequencing consortium.
🧬afb.ukbiobank.ac.uk/
Traitwell retweeted
Did you know that genomics can be used to reduce adverse drug reactions and ensure suitable dosages for patients? Dive into our blog post all about #pharmacogenomics’ role in the NHS: orlo.uk/OWPs2
ALT Two pill-like structures, each with a transparent half and an opaque half. One pill has a gold opaque half, and the other has a silver opaque. Within both pills is a silver DNA helix that can be seen through the transparent half of the pill.
Traitwell retweeted
@GWASCatalog is doing a pretty amazing job of keeping up with the *exponential* increase in number of new GWAS associations.
Since 2010 the number of associations in the GWAS catalog has doubled roughly every 21 months!
An increase in an order of magnitude every 5.75 years!
Traitwell retweeted
The world’s largest collection of full human genomes has just gone live.
UK Biobank — a repository of health, genomic and other biological data — today released complete genome sequences from every one of the 500,000 British volunteers in the database go.nature.com/3uLA03m
Traitwell retweeted
Did you see our announcement? We’ve sequenced all 500,000 of our UK Biobank volunteers’ genomes! Together with the existing data, they form an incredible resource for researchers like @timfrayling
Read more on our website ⬇️ ow.ly/qsyy50QcJ7w
#500KGenomes #genomics
Traitwell retweeted
There is an update on the credential stuffing incident at 23andMe. The company have now submitted the relevant papers to the US Securities and Exchange Commission. 0.1% of accounts were affected which equates to about 14,000 users. techcrunch.com/2023/12/01/23…
Traitwell retweeted
Combining with All of Us and TOPMed, I think, the number of whole genomes touches a million. Unfortunately, the US-based biobanks are not accessible to worldwide researchers as easily as UK Biobank.
Traitwell retweeted
This officially marks the beginning of the era of population-scale whole genomes. The number of genomes of non-Europeans might look tiny compared to that of Europeans, but note, that for some ancestries like South-Asians (n=10,000), it's the largest number sequenced to date.
UK biobank WGS 500k data available
science.org/content/article/…
Traitwell retweeted
Our new study of cannabis use disorder (N>1,000,000) led by @dflevey1 is now online at @NatureGenet.
Article here:
go.nature.com/49Nj1Ou
Sumstats will be made available here:
- dbGAP (bit.ly/47kgf1u)
- Gelernter Lab Webpage (bit.ly/3ETJWJU)
Traitwell retweeted
Genomic and genetic testing comes in all shapes and sizes. We break down the four most common types of testing and look at how they differ so that you can get to grips with them. #GenomicTesting
orlo.uk/8UswL
ALT A photo of a row of 6 test tubes in a stand. All the test tubes have DNA strands suspended in them; the first three test tubes on the left of the row of test tubes have grey DNA, the fourth test tube has red DNA and the remaining two test tubes have grey DNA in them.
Traitwell retweeted
Some asked be about examples - I have a growing list: but here's an interesting one. 🧵⬇
3 papers, 2 grants, 2 unpublished manuscripts - all with fake data. The data however is still in GEO, SRA, GenBank, and not marked as faulty. 😐
@HHS_ORI summary: ori.hhs.gov/content/case-sum…
All the major public #genomics databases have intentionally falsified data in them but researchers either don’t care, don’t think it will affect them, or don’t believe genomic misinformation is a problem.
Traitwell retweeted
NEWS!!! New studies downloads now available in the GWAS Catalog containing COHORTS + clearer indication of which studies have full summary statistics available!
Old download versions will be deprecated and cease to be generated Dec 1st.
Read more here: tinyurl.com/mr3tz32n
Traitwell retweeted
Want to know more about #ADHD and its overlap with other psychiatric disorders and cognition-related phenotypes? Check out this review 📖summarizing the genetic architecture of these comorbidities #genetics 🧬sciencedirect.com/science/ar…
Work led by Marta Ribasés @bcormand & others!
Traitwell retweeted
#DNA is found in nearly every human cell and carries all our unique #genetic information. Learn more in this short animation that introduces key terms and concepts such as nucleotides, DNA bases, and the double helix: orlo.uk/8pRQ8
Traitwell retweeted
The #gnomAD team is proud to announce the release of gnomAD v4! The v4 dataset includes 730,947 exomes & 76,215 genomes, which is ~5x larger than the v2 & v3 releases combined, & includes nearly 120K indivs of non-European genetic ancestry broad.io/gnomad_v4 #ASHG23 (1/11)
Traitwell retweeted
Separated at birth and reunited at 39, the Jim twins discovered strikingly parallel lives. They had both married and divorced women named Linda, were presently married to women named Betty, had sons named James Allan, owned dogs named Toy, drove identical cars, worked in security, and frequented the same Florida beach for vacations.
