
ALT Comparative proteomic analysis of intestine and liver immunomodulatory molecules during acute and chronic infection phases. (A) volcano plots illustrate log2 changes (log2FC) versus statistical significance (–log10 p-values) of schistosomal immunomodulatory proteins (omega-1, IPSE/α-1 isoforms) detected in microdissected intestine (left) and liver (right) tissues surrounding schistosome eggs. The grey dashed horizontal line indicates the statistical significance threshold (p-value < 0.05), while the vertical black line at log2FC = 0 represents no change between conditions. Proteins with low log2FC values are shaded grey. (B) the tables below summarize protein identities, log2FC, p-values, and the infection phase in which they were detected (A = acute, C = chronic).

ALT Comparative proteomic analysis of intestine and liver immunomodulatory molecules during acute and chronic infection phases. (A) volcano plots illustrate log2 changes (log2FC) versus statistical significance (–log10 p-values) of schistosomal immunomodulatory proteins (omega-1, IPSE/α-1 isoforms) detected in microdissected intestine (left) and liver (right) tissues surrounding schistosome eggs. The grey dashed horizontal line indicates the statistical significance threshold (p-value < 0.05), while the vertical black line at log2FC = 0 represents no change between conditions. Proteins with low log2FC values are shaded grey. (B) the tables below summarize protein identities, log2FC, p-values, and the infection phase in which they were detected (A = acute, C = chronic).






















